DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pdgy and Slc27a2

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_113924.2	Gene:	Slc27a2 / 65192	RGDID:	71103	Length:	620	Species:	Rattus norvegicus

Alignment Length:	518	Identity:	103/518 - (19%)
Similarity:	195/518 - (37%)	Gaps:	88/518 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 DRQYTFAQMRDASAAFAVRLQTKFNLQKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTP 164
            |...|:||:...|...|..|.....|::.|.:|:.:.|.|.|....||.::.|..:..:|.....
  Rat    76 DETLTYAQVDRRSNQVARALHDHLGLRQGDCVALFMGNEPAYVWLWLGLLKLGCPMACLNYNIRA 140

  Fly   165 DEIARQLTFSGAKFLVGTVSGFATLSQASKLVGRQIPIAVVRTSAEEALP----EGAIDFSELTS 225
            ..:.......|||.|:.:..                    :..:.||.||    ||...| .::.
  Rat   141 KSLLHCFQCCGAKVLLASPE--------------------LHEAVEEVLPTLKKEGMSVF-YVSR 184

  Fly   226 TQNVRYEDLKAPK--EASADDM--------------VFLPFSSGTTGLPKGVMLSHNNITSNCEQ 274
            |.|....|....|  ..|||.:              |:: ::||||||||...::|:.:...
  Rat   185 TSNTNGVDTVLDKVDGVSADPIPESWRSEVTFTTPAVYI-YTSGTTGLPKAATINHHRLWYG--- 245

  Fly   275 VQASLPL-DLMGPQNTLPGVLPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSI 338
              .||.| ..:...:.:...:|.:|...|.:.:...:..|...|....|....|.....||..::
  Rat   246 --TSLALRSGIKAHDVIYTTMPLYHSAALMIGLHGCIVVGATFALRSKFSASQFWDDCRKYNATV 308

  Fly   339 LNLVPPIALFMINHPKLTQETAPHLKVVMSGAAPIGQHDVER-FLNKFPNTVFKQGYGMTEASPV 402
            :..:..:..::.|.|:...:....:|:.:....   :.||.| |:.:|.:....:.|..||.:..
  Rat   309 IQYIGELLRYLCNTPQKPNDRDHKVKIALGNGL---RGDVWREFIKRFGDIHIYEFYASTEGNIG 370

  Fly   403 VLLTPE-----GNKVYASTGVLPASTEAKIVPLDGSDAKGVGPRTTGELCVRGPQVMAGYL---- 458
            .:..|.     |.:.|....|:    ..:::..|....:.|  |.....|::.|:...|.|
  Rat   371 FMNYPRKIGAVGRENYLQKKVV----RHELIKYDVEKDEPV--RDANGYCIKVPKGEVGLLICKI 429

  Fly   459 -------------NNDEANQV--TFYPGN-WLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPP 507
                         ...|..::  .|..|: :..|||:...|.:...|..||:.:..:.||..|..
  Rat   430 TELTPFFGYAGGKTQTEKKKLRDVFKKGDVYFNSGDLLMIDRENFIYFHDRVGDTFRWKGENVAT 494

  Fly   508 AELEAVLRDHPKILEAAVFGIP---HEFNGEAPRAIVVLRQGEKASAEEISAYVAERVAHYKK 567
            .|:..::.....:.|..|:|:|   ||  |....|.:.:::..:.:.:::..:::|.:..|.:
  Rat   495 TEVADIVGLVDFVEEVNVYGVPVPGHE--GRIGMASIKMKENYEFNGKKLFQHISEYLPSYSR 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	103/518 (20%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	103/518 (20%)
Slc27a2	NP_113924.2	hsFATP2a_ACSVL_like	74..610	CDD:341261	103/518 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342846
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840