DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdgy and AgaP_AGAP003483

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	XP_001688203.2	Gene:	AgaP_AGAP003483 / 5667416	VectorBaseID:	AGAP003483	Length:	540	Species:	Anopheles gambiae

Alignment Length:	561	Identity:	187/561 - (33%)
Similarity:	294/561 - (52%)	Gaps:	42/561 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 QSVSETDKFLHYSPEDGYYKTSPFDPVTIPNVPLHEYVWRDFKKWERRTAAVCVITDRQYTFAQM 108
            |..:..:.|:...|      .:|.| :|:....|.:...:..:|.....|.|..:|.|:|::.::
Mosquito     3 QPAAADESFIVRGP------PAPAD-LTLGAHSLGQLFLKVLQKTPHSVALVDGVTGREYSYQEV 60

  Fly   109 RDASAAFAVRLQTKFNLQKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQLTF 173
            ..::...|..|. ..|:|:.||:||...|..|||:..:.....|.||...||.||..|:...|..
Mosquito    61 LQSALQLAAYLH-DHNIQRGDVVAIVAENRYEYPVTVIALFLVGATVALFNPSYTTRELVHALNV 124

  Fly   174 SGAKFLVGTVSGFATLSQASKLVGRQIPIAVVRTSAEEALPEGAIDFSELTSTQNVRY--EDLKA 236
            :..|.:..:.....:|.:||:.|.:.:    :...:.:||..|. .|:......:.|:  ..::.
Mosquito   125 ARPKLVFVSSLARGSLLKASQTVKQPL----LNVISYDALERGT-SFAHCLQRSSKRFTVASIQP 184

  Fly   237 PKEASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQASL--------PLDLMGPQNTLPGV 293
            .....|:::..:..|||||||||||:::|.|:.:....|:.:|        .||          |
Mosquito   185 MSVEIAEEVAIIVMSSGTTGLPKGVLITHRNVMATMANVRDALDKGLSLHCSLD----------V 239

  Fly   294 LPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQE 358
            ||:||:.| .:.|||.||....:..:|.|:|..::|.:::|:.|.||:||||.:|:..||.:.:.
Mosquito   240 LPWFHVAG-GISMLSWLGANLTVVYLPRFEPRTYLRCIERYRPSFLNMVPPIVVFLAKHPAVLEY 303

  Fly   359 TAPHLKVVMSGAAPIGQHDVERFLN-KFPNTVFKQGYGMTEASPVVLLTPEGNKVYASTGVLPAS 422
            ....::.:..||||:.: :||:.:| :.|....:|||||:|.:..:...........|.|.:.|.
Mosquito   304 DLTSVQTIACGAAPLSR-EVEQLINERLPGIRIRQGYGMSETTQAITFYDRDTLKPGSIGTVRAG 367

  Fly   423 TEAKIVPLDGSDAKGVGPRTTGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDEDGL 487
            ...|:|  |....:.:||...||||.:|..:|.||:.   |.:|....| ||.:||:.:||.||.
Mosquito   368 QMGKVV--DVETGRALGPNQQGELCFKGSLIMKGYIG---AERVIDADG-WLHTGDIGYYDSDGD 426

  Fly   488 FYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVLRQGEKASAE 552
            |:|.||:|||||.|.||||||||||||..:|.:.:.||.|...|..||.|.|.||..:|...:.|
Mosquito   427 FFIVDRLKELIKYKAFQVPPAELEAVLLTNPGVKDCAVVGKADERAGELPLAFVVPTEGIPVTEE 491

  Fly   553 EISAYVAERVAHYKKLEGGVIFVDEVPKNPTGKILRRELKE 593
            ::..||.|||::.|:|.|||.||:|:||..:||||||.|:|
Mosquito   492 QLIQYVDERVSNEKRLRGGVRFVEEIPKTASGKILRRTLRE 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	181/528 (34%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	171/498 (34%)
AgaP_AGAP003483	XP_001688203.2	PLN02246	37..532	CDD:215137	179/518 (35%)
AgaP_AGAP003483	XP_001688203.2	AFD_class_I	45..526	CDD:302604	173/504 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54045
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	1	1.000	-	-		FOG0000951
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
TreeFam	0	0.000	Not matched by this tool.
	6	5.830