DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pdgy and CG8834

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_610779.1	Gene:	CG8834 / 36356	FlyBaseID:	FBgn0033733	Length:	535	Species:	Drosophila melanogaster

Alignment Length:	552	Identity:	144/552 - (26%)
Similarity:	241/552 - (43%)	Gaps:	43/552 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 YSPEDGYYKTSPFDPVTIPNVPLHEYVWRDFKKWERRTAAVCVITDRQYTFAQMRDASAAFAVRL 119
            |:.:|..:..:..:.:...:..:.:.::.:.|.|.:....:|.:.....||.|....|...|..|
  Fly     8 YNEKDNIWSGAKRNSIYNYDTSVGKIIFNNMKNWPKNVCQICDVDGVTVTFEQGLTWSIRIAQYL 72

  Fly   120 QTKFNLQKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVS 184
            : |..|...||:.|...|........:..:..|....:||||.  |:......||..|..:....
  Fly    73 K-KRGLNHKDVIGIAAKNSTYVMPLGVACLMNGTPFHSVNPVL--DDATLTHVFSITKPTLIFCD 134

  Fly   185 G--FATLSQASKLVGRQIPIAVVRTSAEEALPEGAIDFSELTSTQNV-RYEDLKAPKEASADDMV 246
            |  :..:.:|:  ||....|..:....|..  :|.....:.|:|:.: :.|.||    ...|..|
  Fly   135 GQEYDKVHKAT--VGWHPEILTLTDHVEGV--QGIETLLDPTTTEKIYQPEVLK----EGGDQTV 191

  Fly   247 FLPFSSGTTGLPKGVMLSHNNITSNCEQVQASLPLDLMGPQNTLPGVLPFFHIYGLTVVMLSKLG 311
            .:..|||||||||.|.:|::.:      :|.|:   |:..|:.:........|.||...:.|.:
  Fly   192 AILCSSGTTGLPKAVCISNSIL------IQDSM---LITSQSVIYVGSCLDWITGLWAFVFSTV- 246

  Fly   312 QGC-RLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQETAPHLKVVMSGAAPIGQ 375
            .|| |:.:...|.|:.|:..:.||:.:...|.|.....:|..|....:....:..:..|...|..
  Fly   247 FGCTRIISNKAFTPEYFVGLVKKYKINYAVLPPRHLSALITCPDAKPDALAPITHLNYGGGSISL 311

  Fly   376 HDVERFLNKFPNTVFKQGYGMTEASPVVLLTPEGNKVYASTGVLPASTEAKIVP-----LDGSDA 435
            ..::|........:|..||||||...:.:          :.|:...|:..:.||     :...|.
  Fly   312 ATLQRSQELCKTAMFNSGYGMTEVGAITI----------NIGISNVSSAGRPVPGIKIRIVDEDG 366

  Fly   436 KGVGPRTTGELCVRGPQVMAGYLNND-EANQVTFYPGNWLRSGDVAFYDEDGLFYITDRMKELIK 499
            |.:|....||:.|...|...||..|. |..::..:.| |..:||:.::||....||.||.||::|
  Fly   367 KSLGYNQVGEIYVHTGQAWNGYYGNPVETRRMQDFEG-WFHTGDLGYFDEQNFLYIVDRKKEILK 430

  Fly   500 VKGFQVPPAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVLRQGEKASAEEISAYVAERV-A 563
            ..|....|.|:|.|:.:..::.:..|.||..|..|:|..|:||..:|...||:||..:||:|: |
  Fly   431 YNGLHYWPTEIETVIAELSQVQDVCVVGIYDEREGDAAGALVVKSKGATISAKEIVEHVAKRLPA 495

  Fly   564 HYKKLEGGVIFVDEVPKNPTGKILRRELKEKF 595
            ..|:|..||.|.|::|.|..||.:|:..::.|
  Fly   496 TQKQLRAGVQFTDKLPANVNGKTMRKTARDVF 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	141/528 (27%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	137/498 (28%)
CG8834	NP_610779.1	CaiC	20..529	CDD:223395	142/540 (26%)
CG8834	NP_610779.1	AFD_class_I	46..519	CDD:302604	138/504 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45452146
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24096
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940