Protein Alignment pdgy and acs-2

DIOPT Version :9

• Sequence 1: NP_001188590.1
• Gene: pdgy / 32426
• FlyBaseID: FBgn0027601
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_506869.1
• Gene: acs-2 / 3565680
• WormBaseID: WBGene00009221
• Length: 618
• Species: Caenorhabditis elegans
• Alignment Length: 636
• Identity: 154/636 - (24%)
• Similarity: 257/636 - (40%)
• Gaps: 104/636 - (16%)

  Fly    22 RSITTNRRQRTTSTASAQRERTQSVSETDKF------LHYSPEDGY-YKTSPFDPVTIPNVPL-H 78
            |||..:||.....|::.....|.::..||..      :|....:.| :.||        |:|| :
 Worm     2 RSILVSRRFAHVLTSTHAAPSTSNIPTTDSHHLTHPSVHRQHTNSYIHGTS--------NIPLRN 58

  Fly    79 EYVWRDFKKWERRTAAVCVITDRQY----------TFAQMRDASAAFAVRLQTKFNLQKPDVLAI 133
            |.:.:..:....|      :.|:::          |:.:........|..|.| ..|:|.|.:.:
 Worm    59 ETLGQTLRNTTER------VPDKEFCVFSKYPIRKTYEEFYHDVRQMAASLYT-LGLEKGDRVGV 116

  Fly   134 CLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVSGFA----------- 187
            ..||..|:.:.......||:....|||.|..:|:...:..:|.|.|      ||
 Worm   117 WGPNYYEWVVLQYACAFAGVIQVNVNPHYLHEELRFVMRKTGMKVL------FAPKRHKHSNYVH 175

  Fly   188 TLSQASKLVGRQIP-IAVVRTSAEEALPE--------------GAIDFSELT----STQNVRYED 233
            |:.:|...:.|..| :..:::   ..:||              ||..:|:|.    |.:..:.||
 Worm   176 TMLEAMPEMRRGQPGVGHIKS---HDIPELRHIVLYGDDVPVHGAWVYSDLIHAAGSAERAKLED 237

  Fly   234 LKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQASLPLDLMGPQNTLPGVLPFFH 298
            :  .::...|:.|.:.|:|||||.|||..|:|..:.:|.......|..|....:..:|.  |.:|
 Worm   238 M--DRKLRPDEPVNMQFTSGTTGHPKGATLTHFGLNNNAYFAGIRLGWDREDHRICIPN--PLYH 298

  Fly   299 IYGLTVVMLSKLGQGCRLATMP--CFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQETAP 361
            .:|..|.:::.:..| :....|  .:...|...::...:.:.:...|.:.:.::..|.:.|....
 Worm   299 CFGCAVGVINAVNHG-QTVVFPSKSYHVPDIFEAIQNEKCTTMFGTPTMFIDVLKSPLMKQFDIS 362

  Fly   362 HLKVVMSGAAPIGQHDVERFLNKFPNTVFKQGYGMTEASPVVLLTP---EGNKVYASTGVLPAST 423
            .|:..:.|.||......|:.:.:...|.|...||.||.||:|.::.   :..:...|.|.:....
 Worm   363 SLRGGVIGGAPCPMALCEKMVKEMRMTDFSVIYGSTETSPLVTMSELHVDPFERIKSVGSVMPHQ 427

  Fly   424 EAKIVPLDGSDAKGVGPRT--TGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDEDG 486
            |..||     |..||...|  .|||..||...|.||..:.:...:......|.:|||.|..:|||
 Worm   428 ELAIV-----DEFGVPVPTGAKGELWSRGYSTMLGYWADHDKTNLAITRDRWYKSGDTATMNEDG 487

  Fly   487 LFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVLRQGE--KA 549
            ...|..|.:::|...|..|.|.|:|..|.....:.:|.|.|:|.:..||...|.|.||..:  |.
 Worm   488 TINIVGRTRDMIVKGGENVYPTEIEQFLHKLDYVADAHVVGVPDDRYGENICAWVRLRVEDEGKI 552

  Fly   550 SAEEISAYVAERVAHYK-------KLEGGVIFVDEVPKNPTGKILRRELKE 593
            :||.|.......:||||       |.|      .|.|...:||:.:.|:::
 Worm   553 TAEHIKKACKRGMAHYKVPKYVLIKKE------SEFPLTISGKVKKFEIQK 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	139/574 (24%)
		Firefly_Luc_like	99..587	CDD:213279	135/543 (25%)
acs-2	NP_506869.1	PRK08315	46..609	CDD:236236	144/592 (24%)
		FACL_like_2	244..595	CDD:213284	99/364 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.815465	Normalized mean entropy	S2257
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X154
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.660