Protein Alignment pdgy and ACSM2B

DIOPT Version :9

• Sequence 1: NP_001188590.1
• Gene: pdgy / 32426
• FlyBaseID: FBgn0027601
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001098539.1
• Gene: ACSM2B / 348158
• HGNCID: 30931
• Length: 577
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 146/572 - (25%)
• Similarity: 239/572 - (41%)
• Gaps: 118/572 - (20%)

  Fly    82 WRDFKKWERR--TAAVCVITDR----QYTFAQMRDASAAFAVRLQTKFNLQKPDVLAICLPNLPE 140
            |.|.:|..:|  :.|:..:..:    .:.|.::.:.|...|..|.....||:.|.:|:.||.:||
Human    54 WADMEKAGKRLPSPALWWVNGKGKELMWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPE 118

  Fly   141 YPIATLGAIEAGLTVTTVNPVYTP-------DEIARQLTFSGAKFLVGTVSGFATLSQASKLVGR 198
            :.:..||.|.|||       ::.|       .:|..:|..|.||.:   |:|...:.:.. .|..
Human   119 WWLVILGCIRAGL-------IFMPGTIQMKSTDILYRLQMSKAKAI---VAGDEVIQEVD-TVAS 172

  Fly   199 QIPIAVVRTSAEEALPEGAIDFSELTSTQNVRYEDLK-APKEASADDMVFLPFSSGTTGLPKGVM 262
            :.|...::....|...:|.::|.:|.:..:..:..:: ..:||||     :.|:|||:||||...
Human   173 ECPSLRIKLLVSEKSCDGWLNFKKLLNEASTTHHCVETGSQEASA-----IYFTSGTSGLPKMAE 232

  Fly   263 LSHNNITSNCEQ------VQASLPLDLMGP-------QNTLPGVLPFFHIYGLTVVMLSKLGQGC 314
            .|::::....:.      :|||   |:|..       .|.|..:|..:.:...|.|.|
Human   233 HSYSSLGLKAKMDAGWTGLQAS---DIMWTISDTGWILNILGSLLESWTLGACTFVHL------- 287

  Fly   315 RLATMPCFKPDDFMRSLDKYQGSILNLV-PPIALFMINHPKLTQETAPHLKVVMSGA-------- 370
                :|.|.|...:::|..|  .|.::: .||...|:....|:....|||:..::|.
Human   288 ----LPKFDPLVILKTLSSY--PIKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETL 346

  Fly   371 ----APIGQHDVERFLNKFPNTV---------FKQGYGMTEAS--PVVLLTPEGNKVYASTGVLP 420
                |..|. |:..|..:....:         .|.||..|.||  .|.::..:||       |||
Human   347 ENWRAQTGL-DIREFYGQTETGLTCMVSKTMKIKPGYMGTAASCYDVQVIDDKGN-------VLP 403

  Fly   421 ASTEAKIVPLDGSDAKGVGPRTTGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDED 485
            ..||..|    |...|.:.|  .|        :.:||:.|.:..........|| .||....|||
Human   404 PGTEGDI----GIRVKPIRP--IG--------IFSGYVENPDKTAANIRGDFWL-LGDRGIKDED 453

  Fly   486 GLFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVV-----LRQ 545
            |.|....|..::|...|:::.|:|:|..|..||.::|.||...|....||..:|.|:     |..
Human   454 GYFQFMGRADDIINSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSH 518

  Fly   546 GEKASAEEISAYVAERVAHYK---KLEGGVIFVDEVPKNPTGKILRRELKEK 594
            ..:...:|:..:|....|.||   |:|    ||..:||..||||.|.:|::|
Human   519 DPEQLTKELQQHVKSVTAPYKYPRKIE----FVLNLPKTVTGKIQRTKLRDK 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	146/572 (26%)
		Firefly_Luc_like	99..587	CDD:213279	137/544 (25%)
ACSM2B	NP_001098539.1	AFD_class_I	40..568	CDD:388389	146/572 (26%)
		Coenzyme A binding. /evidence=ECO:0000250	469..471		0/1 (0%)
		Coenzyme A binding. /evidence=ECO:0000250	540..542		0/1 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D333840at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920