DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdgy and Slc27a1

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	XP_006509734.1	Gene:	Slc27a1 / 26457	MGIID:	1347098	Length:	657	Species:	Mus musculus

Alignment Length:	512	Identity:	127/512 - (24%)
Similarity:	198/512 - (38%)	Gaps:	100/512 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 TIPNVPLHEYVWRDFKKWERRTAAVCVITDRQ----YTFAQMRDASAAFAVRLQTKFNLQKPDVL 131
            |||.:         |:...||......:.|..    :||||:...|.|.| .|..:......||:
Mouse    88 TIPCI---------FQAVARRQPERLALVDASSGICWTFAQLDTYSNAVA-NLFRQLGFAPGDVV 142

  Fly   132 AICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVSGFATLSQASKLV 196
            |:.|...||:....||..:||:....:|.....:.:|..|..|.||.|:......|.:::.|:.:
Mouse   143 AVFLEGRPEFVGLWLGLAKAGVVAALLNVNLRREPLAFCLGTSAAKALIYGGEMAAAVAEVSEQL 207

  Fly   197 GRQIPIAVVRTSAEEALPEGAIDFSELTSTQNVRYEDLKAPKEASA-------DDMVFLPFSSGT 254
            |:    ::::..:.:..||     |.|..||.:.....:||....|       ||.:|..::|||
Mouse   208 GK----SLLKFCSGDLGPE-----SILPDTQLLDPMLAEAPTTPLAQAPGKGMDDRLFYIYTSGT 263

  Fly   255 TGLPKGVMLSHNNITSNCEQVQASLPLDLMGPQNTLPGVLPFFH------------IYGLTVVML 307
            |||||..::.|:...........|..   |...:.|...||.:|            |||||||:.
Mouse   264 TGLPKAAIVVHSRYYRIAAFGHHSYS---MRAADVLYDCLPLYHSAGNIMGVGQCVIYGLTVVLR 325

  Fly   308 SKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQETAPHLKV-VMSGAA 371
            .|            |....|.....||..:::..:..|..:::..|....|....::: |.:|..
Mouse   326 KK------------FSASRFWDDCVKYNCTVVQYIGEICRYLLRQPVRDVEQRHRVRLAVGNGLR 378

  Fly   372 PIGQHDVERFLNKFPNTVFKQGYGMTEASPVVLLTPEGNKVYAS-------TGVLPAS----TEA 425
            |.   ..|.|..:|......:.||.||.: ..:...:| ||.:.       |.|.|..    .|.
Mouse   379 PA---IWEEFTQRFGVPQIGEFYGATECN-CSIANMDG-KVGSCGFNSRILTHVYPIRLVKVNED 438

  Fly   426 KIVPLDGSDAKGVGPRTTGELCVRGPQVMAGYLN-----------------NDEANQVTFYPGN- 472
            .:.||..|:...: |...||     |.::.|.:|                 |.:.....|..|:
Mouse   439 TMEPLRDSEGLCI-PCQPGE-----PGLLVGQINQQDPLRRFDGYVSDSATNKKIAHSVFRKGDS 497

  Fly   473 -WLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGI 528
             :| ||||...||.|..|..||..:..:.:|..|...|:||||.......:.||:|:
Mouse   498 AYL-SGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEVEAVLSRLLGQTDVAVYGV 553

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	124/506 (25%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	121/484 (25%)
Slc27a1	XP_006509734.1	AFD_class_I	115..622	CDD:418409	120/476 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839039
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840