DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdgy and SPCC1827.03c

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001342732.1	Gene:	SPCC1827.03c / 2539253	PomBaseID:	SPCC1827.03c	Length:	512	Species:	Schizosaccharomyces pombe

Alignment Length:	517	Identity:	146/517 - (28%)
Similarity:	243/517 - (47%)	Gaps:	44/517 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 AAVCVITDRQYTFAQMRDASAAFAVRLQ---TKFNLQKPDVLAICLPNLPEYPIATLGAIEAGLT 154
            |.|....:.:.:|:::|.|    .:.||   ....::..|.:.|.:||..|:.:|..........
pombe    18 ALVAPSLNAELSFSELRIA----IMDLQRQIASLGIKVGDPVNIAIPNGLEFVVAFYAVSWQRAI 78

  Fly   155 VTTVNPVYTPDEIARQLTFSGAKFLV---GTVSGFATLSQASKLVGRQIPIAVVRTSAEEA-LPE 215
            ...:|..|...|....:....:|.::   |:|:......:|:|    ::.:||    ||.| .|:
pombe    79 CGPLNSNYKQSEFEFYIDDLKSKLVIVPEGSVAANTPAVRAAK----KLSVAV----AELAWCPK 135

  Fly   216 GAIDFSELTSTQNVRYEDLK--APKE---ASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQV 275
            ..:       .:.|.:|..|  ||:.   ...||::.:..:|||||.||.|.|:|.|:..:...:
pombe   136 SRL-------VRIVHFEGAKINAPQPLGLPQPDDVMLVLHTSGTTGRPKVVPLTHKNLCRSIHNI 193

  Fly   276 QASLPLDLMGPQNTLPGVLPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILN 340
            ..|..||   |::|...|:|.||::||...:||.|..|......|.|....|.:...:|..:...
pombe   194 TTSYRLD---PRDTSYVVMPLFHVHGLLCGLLSTLASGGCAVVPPKFSAHSFWKEFIQYGATWYT 255

  Fly   341 LVPPIALFMINHPKLTQETAPHLKVVMSGAAPIGQHDVERFLNKFPNTVFKQGYGMTEASPVVLL 405
            .||.|...::..|  ..:..|.::.:.|.::|:....:.:....|...|. :.|.|||||..:..
pombe   256 AVPTIHQILLRTP--PPKPLPRIRFIRSCSSPLAPPVLSKLEATFRAPVL-EAYAMTEASHQMTT 317

  Fly   406 TPEGNKVYASTGV-LPASTEAKIVPLDGSDAKGVGPR-TTGELCVRGPQVMAGYLNNDEANQVTF 468
            .|....|:....| .|...|.||:...|::.    |: ..||:||||..|..|||||..||:.:|
pombe   318 NPLPPLVHKPHSVGKPFGVELKILDQKGNEM----PQGKEGEICVRGINVTKGYLNNPAANKSSF 378

  Fly   469 YPGNWLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGIPHEFN 533
            ....:.|:||....|:||..:||.|:|||:...|.::.|||::|||..||.:.||..|.:|.|..
pombe   379 TKDRFFRTGDEGKLDKDGYVFITGRIKELVNRGGEKISPAEIDAVLMQHPDVSEAVCFAVPDEKY 443

  Fly   534 GEAPRAIVVLRQGEKASAEEISAYVAERVAHYKKLEGGVIFVDEVPKNPTGKILRRELKEKF 595
            |:..:|.:....|:..:.:::..|:.::||.: |:.....|.|.:||..|||:.||.:.:.|
pombe   444 GQDIQAAINPVAGKTVTPKQLHDYLEQKVAAF-KIPKKFYFTDRIPKTATGKVQRRLVCDAF 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	145/515 (28%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	141/501 (28%)
SPCC1827.03c	NP_001342732.1	FACL_fum10p_like	160..502	CDD:213292	113/352 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	176	1.000	Inparanoid score	I1153
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47353
orthoMCL	1	0.900	-	-		OOG6_100107
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R434
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.790