Protein Alignment pdgy and ACSL6

DIOPT Version :10

• Sequence 1: NP_572988.1
• Gene: pdgy / 32426
• FlyBaseID: FBgn0027601
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_056071.2
• Gene: ACSL6 / 23305
• HGNCID: 16496
• Length: 722
• Species: Homo sapiens
• Alignment Length: 721
• Identity: 146/721 - (20%)
• Similarity: 241/721 - (33%)
• Gaps: 212/721 - (29%)

  Fly     1 MNPAAQLLRMRSATAFGSAATRSITTNRRQRTTSTASAQR------ERTQSVSETDKFLHYSPED 59
            :.|...||...........|.||:..:..|..|......|      .|..|:|.....|
Human    76 LQPPCNLLMQSEEVEDSGGARRSVIGSGPQLLTHYYDDARTMYQVFRRGLSISGNGPCL------ 134

  Fly    60 GYYKTSPFDPVTIPNVPLHEYVWRDFKKWERRTAAVCVITDRQYTFAQMRDASAAFAVRLQTKFN 124
            |:.|            |...|.|..:::          :.||         |....:..||....
Human   135 GFRK------------PKQPYQWLSYQE----------VADR---------AEFLGSGLLQHNCK 168

  Fly   125 LQKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVS-GFAT 188
            ......:.:...|.||:.|..|......:.|..:.....|..|         ::::.|.. ....
Human   169 ACTDQFIGVFAQNRPEWIIVELACYTYSMVVVPLYDTLGPGAI---------RYIINTADISTVI 224

  Fly   189 LSQASKLV-------GRQIP---IAVVRTSAEEALPE-----GAIDFSELTSTQNVRYEDLKAPK 238
            :.:..|.|       .::.|   :.::....||||.|     |.: ...:.:.::...|:.:||.
Human   225 VDKPQKAVLLLEHVERKETPGLKLIILMDPFEEALKERGQKCGVV-IKSMQAVEDCGQENHQAPV 288

  Fly   239 EASADDMVFLPFSSGTTGLPKGVMLSHNNITSN---------------CEQVQASLPLDLMGPQN 288
            ....||:..:.|:|||||.|||.||:|.|:.::               |..|..|
Human   289 PPQPDDLSIVCFTSGTTGNPKGAMLTHGNVVADFSGFLKVTESQWAPTCADVHIS---------- 343

  Fly   289 TLPGVLPFFHIYGLTVVMLSKLGQG---CRLATMPCFKPD-----DFMRSLDKYQGSILNLVP-- 343
                .||..|       |..::.|.   |....:..|:.|     |.|::|..   :|..:||
Human   344 ----YLPLAH-------MFERMVQSVVYCHGGRVGFFQGDIRLLSDDMKALCP---TIFPVVPRL 394

  Fly   344 --------------PIALFMINHP-------------------------KLTQETAPHLKVVMSG 369
                          |:..:::...                         |:.......::::::|
Human   395 LNRMYDKIFSQANTPLKRWLLEFAAKRKQAEVRSGIIRNDSIWDELFFNKIQASLGGCVRMIVTG 459

  Fly   370 AAPIGQHDVERFLNKFPNTVFKQGYGMTEASPVVLLTPEGNKVYASTGVLPASTEAKIVPLDGSD 434
            ||| ....|..||.........:|||.||.:.....|..|:......|........|:|.::..:
Human   460 AAP-ASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWTSGHVGAPLPCNHIKLVDVEELN 523

  Fly   435 ---AKGVGPRTTGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDEDGLFYITDRMKE 496
               .||     .||:|||||.|..|||.:.:..:.......||.:||:..:...|...|.||.|.
Human   524 YWACKG-----EGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDIGKWLPAGTLKIIDRKKH 583

  Fly   497 LIKV-KGFQVPPAELEAV-LRDHP--------KILEAAVFGI----PHEF--------------- 532
            :.|: :|..|.|.::|.: :|..|        ..|:|.:.||    |...
Human   584 IFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPEVMPSWAQKRGIEGTYAD 648

  Fly   533 ---NGEAPRAIV--VLRQGEKA---SAEEISAYVAERVAHYKKLEGGVIFVDEVPKNPTGKILRR 589
               |.:..:||:  ::|.|:::   |.|::.|.         .:...:..|......||.|..|.
Human   649 LCTNKDLKKAILEDMVRLGKESGLHSFEQVKAI---------HIHSDMFSVQNGLLTPTLKAKRP 704

  Fly   590 ELKEKF 595
            ||:|.|
Human   705 ELREYF 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_572988.1	Firefly_Luc_like	93..587	CDD:341237	123/613 (20%)
ACSL6	NP_056071.2	LC-FACS_euk	141..719	CDD:341250	130/638 (20%)