Protein Alignment pdgy and DIP2A

DIOPT Version :9

• Sequence 1: NP_001188590.1
• Gene: pdgy / 32426
• FlyBaseID: FBgn0027601
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_011527794.1
• Gene: DIP2A / 23181
• HGNCID: 17217
• Length: 1607
• Species: Homo sapiens
• Alignment Length: 601
• Identity: 130/601 - (21%)
• Similarity: 210/601 - (34%)
• Gaps: 155/601 - (25%)

  Fly    92 TAAVCVITDRQYTFAQMRDASAAFAVRLQTKFNLQKPDVLAICLPNLPEYPIATLGAIEAGLTVT 156
            :.|.||         |:...:...|..|..|..|...|.:|:..|...:...|..|.:..|....
Human  1051 STATCV---------QLHKRAERVAAALMEKGRLSVGDHVALVYPPGVDLIAAFYGCLYCGCVPV 1106

  Fly   157 TVNPVYTPDEIARQLTFSGAKFLVGTVSGFATLSQASKLVGRQIPIAVVRTSAEEALPEGAIDFS 221
            ||.|.: |..:...|.         ||.....:|:::.::..|....::|:....|    |:|..
Human  1107 TVRPPH-PQNLGTTLP---------TVKMIVEVSKSACVLTTQAVTRLLRSKEAAA----AVDIR 1157

  Fly   222 ELTSTQNVRYEDLKAPKEASA------DDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQV----- 275
            ...:..:.  :|:...|.||.      |.:.:|.||..|||:..||.:||...::.|..:
Human  1158 TWPTILDT--DDIPKKKIASVFRPPSPDVLAYLDFSVSTTGILAGVKMSHAATSALCRSIKLQCE 1220

  Fly   276 -----QASLPLD---------------LMGPQNTLPGVLPFFHIYGLTVVMLSKLGQ------GC 314
                 |.::.||               ..|.|:.|   :|...:.....:.||.:.|      .|
Human  1221 LYPSRQIAICLDPYCGLGFALWCLCSVYSGHQSVL---VPPLELESNVSLWLSAVSQYKARVTFC 1282

  Fly   315 RLATMP-CFKPDDFMRSLDKYQGSILNLVPPIALFMINHPK--LTQETAPHLK------------ 364
            ..:.|. |.|.......:.:.:|..|:.|....:.....|:  |||..:...|
Human  1283 SYSVMEMCTKGLGAQTGVLRMKGVNLSCVRTCMVVAEERPRIALTQSFSKLFKDLGLPARAVSTT 1347

  Fly   365 --------VVMSGAA---PIG--------QHDVERFLNKFPNTVFKQGYGMTEASPVVLLTPEGN 410
                    :.:.|.|   |..        :||..|.:.:              .||..|...|..
Human  1348 FGCRVNVAICLQGTAGPDPTTVYVDMRALRHDRVRLVER--------------GSPHSLPLMESG 1398

  Fly   411 KVYASTGVLPASTEAKIVPLDGSDAKGVGPRTTGELCVRGPQVMAGY--LNNDEANQVTFYPGN- 472
            |:.....|:.|.||.| .||        |....||:.|..|....||  :..:||.....:...
Human  1399 KILPGVKVIIAHTETK-GPL--------GDSHLGEIWVSSPHNATGYYTVYGEEALHADHFSARL 1454

  Fly   473 --------WLRSGDVAFY------DEDG----LFYITDRMKELIKVKGFQVPPAELE-AVLRDHP 518
                    |.|:|.:.|.      |..|    ..|:...:.|.::::|.:..|.::| :|:|.|.
Human  1455 SFGDTQTIWARTGYLGFLRRTELTDASGGRHDALYVVGSLDETLELRGMRYHPIDIETSVIRAHR 1519

  Fly   519 KILEAAVFGIPHEFNGEAPRAIVVLRQGEKASAEEISAYVAERV--AHYKKLEGGVIFVDE--VP 579
            .|.|.|||...:..      .:||...|.:..|.::.|.|...|  .|| .:.|.|:.||.  :|
Human  1520 SIAECAVFTWTNLL------VVVVELDGLEQDALDLVALVTNVVLEEHY-LVVGVVVIVDPGVIP 1577

  Fly   580 KNPTGKILRRELKEKF 595
            .|..|:..|..|::.|
Human  1578 INSRGEKQRMHLRDGF 1593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	129/599 (22%)
		Firefly_Luc_like	99..587	CDD:213279	124/584 (21%)
DIP2A	XP_011527794.1	DMAP_binding	9..158	CDD:283995
		CaiC	360..959	CDD:223395
		AFD_class_I	392..956	CDD:302604
		AMP-binding	1027..1501	CDD:278902	100/500 (20%)
		AFD_class_I	1044..1596	CDD:302604	130/601 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0318
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900