Protein Alignment pdgy and ACSL3

DIOPT Version :9

• Sequence 1: NP_001188590.1
• Gene: pdgy / 32426
• FlyBaseID: FBgn0027601
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001341087.1
• Gene: ACSL3 / 2181
• HGNCID: 3570
• Length: 720
• Species: Homo sapiens
• Alignment Length: 596
• Identity: 140/596 - (23%)
• Similarity: 239/596 - (40%)
• Gaps: 168/596 - (28%)

  Fly   126 QKPDV-LAICLPNLPEYPI----------------ATLG--AIEAGLTVTTVNPVYTPDEIARQL 171
            |||.. :||......|:.|                ||||  ||...|..|.|..:.|    :::|
Human   156 QKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIIT----SKEL 216

  Fly   172 TFSGAKFLVG---------TVSGF-ATLSQASKLVGRQIPIAVVRT-SAEEALPEGAIDFSELTS 225
            ..:..|.:|.         ||.|. .|.|:..|.:       :|.| :|.|||...|       |
Human   217 LQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGI-------IVHTMAAVEALGAKA-------S 267

  Fly   226 TQNVRYEDLKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQASLPLDLMGPQNTL 290
            .:|      :...:....|:..:.::||:||||||||:||:||.:....:...:|  .:|.::..
Human   268 MEN------QPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIP--ELGEEDVY 324

  Fly   291 PGVLPFFHIYGLTVVMLSKLGQGCRLA---------------------------TMPCFKPDDFM 328
            .|.||..|:..|:..::. |..|||:.                           |:....|:
Human   325 IGYLPLAHVLELSAELVC-LSHGCRIGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPE--- 385

  Fly   329 RSLDKYQGSILNLVPPIA-----LFMI-------------NHP--------KLTQETAPHLKVVM 367
             .:|:...:::|.|..::     ||::             |.|        |:......::::::
Human   386 -IMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLL 449

  Fly   368 SGAAPIGQHDVERFLNKFPNTVFKQGYGMTEASPVVLLTPEGNKVY-ASTGVLPASTEAKIVPLD 431
            .|.||:.. ..:||:|........||||:||::....:    ::|: .:||.:.|......:.|.
Human   450 CGGAPLSA-TTQRFMNICFCCPVGQGYGLTESAGAGTI----SEVWDYNTGRVGAPLVCCEIKLK 509

  Fly   432 GSDAKGV----GPRTTGELCVRGPQVMAGYLNNDEANQVTFYPG----NWLRSGDVAFYDEDGLF 488
            ..:..|.    .|...||:.:.|..|..||..|:...:..|:..    .||.:||:..::.||..
Human   510 NWEEGGYFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCL 574

  Fly   489 YITDRMKELIKVK-GFQVPPAELEAVLRDHPKI---------LEAAVFG--IPHEFNGEAPRAIV 541
            .|.||.|:|:|:: |..|...::||.|::.|.:         ..:.|.|  :|::      :.:.
Human   575 KIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDNICAYANSYHSYVIGFVVPNQ------KELT 633

  Fly   542 VL--RQGEKASAEEI--SAYVAERV----------AHYKKLEGGV-IFVDEVPKNP-TG------ 584
            .|  ::|.|.:.||:  |..:...|          |..:|.|..| |.:...|..| ||
Human   634 ELARKKGLKGTWEELCNSCEMENEVLKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAF 698

  Fly   585 KILRRELKEKF 595
            |:.|:|||..:
Human   699 KLKRKELKTHY 709

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	140/594 (24%)
		Firefly_Luc_like	99..587	CDD:213279	136/586 (23%)
ACSL3	NP_001341087.1	AFD_class_I	30..717	CDD:418409	140/596 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148980
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840