DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pdgy and Acsbg1

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_599216.1	Gene:	Acsbg1 / 171410	RGDID:	708557	Length:	721	Species:	Rattus norvegicus

Alignment Length:	732	Identity:	167/732 - (22%)
Similarity:	264/732 - (36%)	Gaps:	224/732 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 RSITTNRRQRTTSTASAQRERTQSVSETDKFLHYSPEDG--YYKTSPFD---PVTIPNVPLHEYV 81
            |:::..........::.::.|..|:..:::.|..:..||  ..:..||.   |.|:     |:..
  Rat    47 RTLSKESPSHGLELSAPEKARAASLDASEEALWTTRADGRVRLRLEPFCTQLPYTV-----HQMF 106

  Fly    82 WR-----------DFK---KWERRTAAVCVITDRQYTFAQMRDASAAFAVRLQTKFNLQKPDVLA 132
            :.           .||   ||||       |:..|| :...|..:..|     .|..|::...:|
  Rat   107 YEALDKYGNLSALGFKRKDKWER-------ISYYQY-YLIARKVAKGF-----LKLGLERAHSVA 158

  Fly   133 ICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEI--------ARQLTFSGAKFLVGTVSGFATL 189
            |...|.||:..:.:|.:.||..||.:....:|:..        |..:.....|.|...:..:..|
  Rat   159 ILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAHDCRANVIVVDTQKQLEKILKIWKDL 223

  Fly   190 SQASKLVGRQIP----IAVVRTSAE-----EALPEGAIDFSELTSTQNVRYEDLKAPKEASADDM 245
            .....:|..|.|    :|.|.|..|     :.:||.|:|  .:..||.        |.:...
  Rat   224 PHLKAVVIYQEPPPKKMANVYTMEELIELGQEVPEEALD--AIIDTQQ--------PNQCCV--- 275

  Fly   246 VFLPFSSGTTGLPKGVMLSHNNIT------SNCEQVQASLPLDLMGPQNTLPGVLPFFHIYGLTV 304
              |.::|||||.|||||||.:|||      |....:|   |.::.  |..:...||..||    .
  Rat   276 --LVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIQ---PAEVQ--QEVVVSYLPLSHI----A 329

  Fly   305 VMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNL---VPPIALFMINHPKLTQETAPHLKVV 366
            ..:..|..|.:.....||...|.::      |:::|.   |.|.:...:  |::.::....::.|
  Rat   330 AQIYDLWTGIQWGAQVCFADPDALK------GTLVNTLREVEPTSHMGV--PRVWEKIMERIQEV 386

  Fly   367 MS-----------------------------------------------------------GAAP 372
            .:                                                           ||||
  Rat   387 AAQSGFIRRKMLLWAMSVTLEQNLTCPSNDLKPFTSRLADYLVLARVRQALGFAKCQKNFYGAAP 451

  Fly   373 IGQHDVERFLNKFPNTVFKQGYGMTEAS-PVVLLTPEGNKVYASTGVLPASTEAKIVPLDGSDAK 436
            :.......||..  |.....|||::|:: |..:.:|...::|:|..|:|...    |.|...||.
  Rat   452 MTAETQRFFLGL--NIRLYAGYGLSESTGPHFMSSPYNYRLYSSGRVVPGCR----VKLVNQDAD 510

  Fly   437 GVGPRTTGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDEDGLFYITDRMKELIKVK 501
            |:     ||:|:.|..:..||||.::..........||.:||:...|:||..|||.|:||||...
  Rat   511 GI-----GEICLWGRTIFMGYLNMEDKTHEAIDSEGWLHTGDMGRLDDDGFLYITGRLKELIITA 570

  Fly   502 GFQ-VPPAEL-EAVLRDHPKILEAAVFGIPHEF-----------NGEAPRAIVVL---------R 544
            |.: |||..: |||..:.|.|..|.:.|...:|           |.|.......|         |
  Rat   571 GGENVPPVPIEEAVKMELPIISSAMLIGDQRKFLSMLLTLKCTLNPETSEPTDNLTEQAVEFCQR 635

  Fly   545 QGEKASA--------------------EEISAYVAERVAHYKK---------LEGGVIFVDEVPK 580
            .|.|||.                    :.::|..|.|..|.:|         :.||.:
  Rat   636 VGSKASTVSEIVGQKDEAVYQAIHEGIQRVNANAAARPYHIQKWAILERDFSISGGEL------- 693

  Fly   581 NPTGKILRRELKEKFSD 597
            .||.|:.|..:.||:.|
  Rat   694 GPTMKLKRLTVLEKYKD 710

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	155/668 (23%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	145/624 (23%)
Acsbg1	NP_599216.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64		1/16 (6%)
Acsbg1	NP_599216.1	ACSBG_like	122..716	CDD:341256	155/652 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342842
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930