Protein Alignment pdgy and AgaP_AGAP002718

DIOPT Version :9

• Sequence 1: NP_001188590.1
• Gene: pdgy / 32426
• FlyBaseID: FBgn0027601
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_312208.4
• Gene: AgaP_AGAP002718 / 1273249
• VectorBaseID: AGAP002718
• Length: 600
• Species: Anopheles gambiae
• Alignment Length: 604
• Identity: 298/604 - (49%)
• Similarity: 393/604 - (65%)
• Gaps: 31/604 - (5%)

  Fly    10 MRSATAFGSAATRSI--------TTNRRQRTTSTASAQR-ERTQSVSETDKFLH---YSPEDGYY 62
            |||   ||..|.|.|        ...|.||..|    || .|..|.....|:|.   :.||:|..
Mosquito     2 MRS---FGPLAARLIGQGQGLPAPVGRHQRYWS----QRCVRLLSTKRQVKYLEDTIFPPENGLE 59

  Fly    63 KTSPFD-PVTIPNVPLHEYVWRDFKKWERRTAAVCVITDRQYTFAQMRDASAAFAVRLQTKFNLQ 126
            :.|.:| .:.:|:|.|..|:|..|.:|..:||.||.||.|.||:..:||..||.|:|||.|.:|.
Mosquito    60 QNSLYDNNIPVPHVTLDHYLWDQFSQWANKTAVVCGITGRNYTYGTLRDHCAALAIRLQRKLHLN 124

  Fly   127 KPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVSGFATLSQ 191
            ....||:||||:||:|:.|.|.|||||.|||:||:||.:||:|||..|.||.|:|..|.:|.|.:
Mosquito   125 FGQTLAVCLPNIPEFPLVTFGGIEAGLVVTTINPIYTAEEISRQLVDSDAKVLIGLASNYAVLRE 189

  Fly   192 ASKLVGRQIPIAVVRTSAEEALPEGAIDFSELTSTQNVRYEDLKAPKEASADDMVFLPFSSGTTG 256
            |::...|.|||..:|.:.:|:||.|||||:||::.:.:.|.:|: ..:.:|||:||||:||||||
Mosquito   190 AAQQAKRDIPIVCIRCTNDESLPAGAIDFAELSNPKGIHYSELR-QHDRTADDIVFLPYSSGTTG 253

  Fly   257 LPKGVMLSHNNITSNCEQVQAS-------LP-LDLMGPQNTLPGVLPFFHIYGLTVVMLSKLGQG 313
            :||||.|:|.||.||.|.:...       || .|..  |:.||.||||||||||||.|:|||.||
Mosquito   254 MPKGVELTHLNIVSNSEMLAVKAGNGTVVLPTTDTF--QDVLPCVLPFFHIYGLTVTMISKLRQG 316

  Fly   314 CRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQETAPHLKVVMSGAAPIGQHDV 378
            |:|.|:|.||||.|:.:|.:::|::|:|||||.:|:.:|..:.......::.|.|||||:|..|.
Mosquito   317 CKLVTLPNFKPDTFLNALAEHKGTVLHLVPPIIIFLGHHDGVKPRHTDSIRNVFSGAAPMGTPDA 381

  Fly   379 ERFLNKFPNTVFKQGYGMTEASPVVLLTPEGNKVYASTGVLPASTEAKIVPLDGSDAKGVGPRTT 443
            |||..:.||..|.||||:||.:||||:...|::.|||.|.....|:||||.|:......:||..:
Mosquito   382 ERFTARAPNAEFIQGYGLTETAPVVLMGALGSRNYASVGSPCPRTQAKIVDLNDPTNTALGPNQS 446

  Fly   444 GELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPPA 508
            |||.|||||||.||.||.:|.......|.|||:||:|.|||...||||||:||||||||||||||
Mosquito   447 GELLVRGPQVMKGYHNNRKATDEMIIEGGWLRTGDIAHYDEQLQFYITDRLKELIKVKGFQVPPA 511

  Fly   509 ELEAVLRDHPKILEAAVFGIPHEFNGEAPRAIVVLRQGEKASAEEISAYVAERVAHYKKLEGGVI 573
            |||.:||.|..:.:|||.|:||...||.|||.||.:.|.:.|.:.:.|::||:||.||:|||||.
Mosquito   512 ELEELLRSHEAVADAAVVGMPHPVAGEVPRAFVVPKAGARVSEDALKAFIAEKVAVYKRLEGGVT 576

  Fly   574 FVDEVPKNPTGKILRRELK 592
            |:|.:|||.:||||||:||
Mosquito   577 FLDSIPKNASGKILRRQLK 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	273/524 (52%)
		Firefly_Luc_like	99..587	CDD:213279	257/495 (52%)
AgaP_AGAP002718	XP_312208.4	PLN02246	68..595	CDD:215137	273/529 (52%)
		AFD_class_I	97..590	CDD:302604	257/495 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	418	1.000	Domainoid score	I1953
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H80284
Inparanoid	1	1.050	551	1.000	Inparanoid score	I2713
OMA	1	1.010	-	-		QHG54045
OrthoDB	1	1.010	-	-		D100051at6656
OrthoFinder	1	1.000	-	-		FOG0000951
OrthoInspector	1	1.000	-	-		oto110678
Panther	1	1.100	-	-	LDO	PTHR24096
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X154
TreeFam	0	0.000	Not matched by this tool.
	11	11.080