DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdgy and Acsl3

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_476448.1	Gene:	Acsl3 / 114024	RGDID:	70552	Length:	720	Species:	Rattus norvegicus

Alignment Length:	482	Identity:	115/482 - (23%)
Similarity:	193/482 - (40%)	Gaps:	117/482 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 QKPDV-LAICLPNLPEYPI----------------ATLG--AIEAGLTVTTVNPVYTPDEIARQL 171
            |||.. :||......|:.|                ||||  ||..||..|.|..:.|..|:.:
  Rat   156 QKPKANIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQ-- 218

  Fly   172 TFSGAKFLVGTVSGFATLSQASKLVGRQIPIAVV--RTSAEEALPEGAIDFSELTSTQNVRYE-- 232
                           ..|.....||.|...|..|  :.......|:|.| ...:.:.|.:..:
  Rat   219 ---------------TKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGVI-VHTMAAVQALGVKAD 267

  Fly   233 -DLKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQASLPLDLMGPQNTLPGVLPF 296
             |.||..:....|:..:.::||:||:|||||:||:||.::...:...:|  .:|.::...|.||.
  Rat   268 VDKKAHSKPLPSDIAVIMYTSGSTGIPKGVMISHSNIIASITGMARRIP--RLGEEDVYIGYLPL 330

  Fly   297 FHIYGLTVVMLSKLGQGCRLA---------------------------TMPCFKPDDFMRSLDKY 334
            .|:..|:..::. |..|||:.                           |:....|:    .:|:.
  Rat   331 AHVLELSAELVC-LSHGCRIGYSSPQTLADQSSKIKKGSKGDTSVLKPTLMAAVPE----IMDRI 390

  Fly   335 QGSILNLVPPIALFMIN------HPKLTQET--------------------APHLKVVMSGAAPI 373
            ..:::|.|..::.|..|      :.|:.|.:                    ..:::|::.|.||:
  Rat   391 YKNVMNKVNEMSAFQRNLFILAYNYKMEQISKGCSTPLCDRFVFRNVRRLLGGNIRVLLCGGAPL 455

  Fly   374 GQHDVERFLNKFPNTVFKQGYGMTEASPVVLLTPEGNKVY-ASTGVLPASTEAKIVPLDGSDAKG 437
            .. ..:||:|........||||:||::....:|    :|: .:||.:.|......:.|...:..|
  Rat   456 SA-TTQRFMNICFCCPVGQGYGLTESTGAGTIT----EVWDYNTGRVGAPLVCCEIKLKNWEEGG 515

  Fly   438 V----GPRTTGELCVRGPQVMAGYLNNDEANQVTFYPG----NWLRSGDVAFYDEDGLFYITDRM 494
            .    .|...||:.:.|..|..||..|:...:..|:..    .||.:||:..:|.||...|.||.
  Rat   516 YFNTDKPHPRGEILIGGQNVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFDPDGCLKIIDRK 580

  Fly   495 KELIKVK-GFQVPPAELEAVLRDHPKI 520
            |:|:|:: |..|...::||.|::.|.|
  Rat   581 KDLVKLQAGEYVSLGKVEAALKNLPLI 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	115/482 (24%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	115/482 (24%)
Acsl3	NP_476448.1	PLN02387	30..717	CDD:215217	115/482 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166342847
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930