Protein Alignment pdgy and SLC27A2

DIOPT Version :9

• Sequence 1: NP_001188590.1
• Gene: pdgy / 32426
• FlyBaseID: FBgn0027601
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_003636.2
• Gene: SLC27A2 / 11001
• HGNCID: 10996
• Length: 620
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 116/539 - (21%)
• Similarity: 199/539 - (36%)
• Gaps: 90/539 - (16%)

  Fly    81 VWRDFKKWERRT--AAVCVITDRQYTFAQMRDASAAFAVRLQTKFNLQKPDVLAICLPNLPEYPI 143
            :.|.|.:..|:|  ....:..|...|:||:...|...|..|.....|::.|.:|:.:.|.|.|..
Human    55 ILRAFLEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVW 119

  Fly   144 ATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVSGFATLSQASKLVGRQIPIAVVRTS 208
            ..||.::.|..:..:|.......:.......|||.|               ||..::..||
Human   120 LWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVL---------------LVSPELQAAV---- 165

  Fly   209 AEEALPE-----------------GAIDFSELTSTQNVRYEDLKAPKEASADDMVFLP----FSS 252
             ||.||.                 ..|| |.|.....|..|.:  |:...::.....|    ::|
Human   166 -EEILPSLKKDDVSIYYVSRTSNTDGID-SFLDKVDEVSTEPI--PESWRSEVTFSTPALYIYTS 226

  Fly   253 GTTGLPKGVMLSHNNITSNCEQVQAS-LPLDLMGPQNTLPGVLPFFHIYGLTVVMLSKLGQGCRL 316
            |||||||..|::|..|.........| |..|     :.:...|||:|...|.:.:...:..|..|
Human   227 GTTGLPKAAMITHQRIWYGTGLTFVSGLKAD-----DVIYITLPFYHSAALLIGIHGCIVAGATL 286

  Fly   317 ATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQETAPHLKVVMSGAAPIGQHDVER- 380
            |....|....|.....||..:::..:..:..::.|.|:...:....:::.:....   :.||.|
Human   287 ALRTKFSASQFWDDCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGL---RGDVWRQ 348

  Fly   381 FLNKFPNTVFKQGYGMTEASPVVLLTPEGNKVYASTGVLPASTEAKIVPLD--GSDAKGVGP-RT 442
            |:.:|.:....:.|..||.:  :.......||.|...|  ...:.||:..|  ..|.:...| |.
Human   349 FVKRFGDICIYEFYAATEGN--IGFMNYARKVGAVGRV--NYLQKKIITYDLIKYDVEKDEPVRD 409

  Fly   443 TGELCVRGPQVMAGYLNNDEANQVTFYPGN---------------------WLRSGDVAFYDEDG 486
            ....|||.|:...|.| ..:..|:|.:.|.                     :..|||:...|.:.
Human   410 ENGYCVRVPKGEVGLL-VCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHEN 473

  Fly   487 LFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVFGI---PHEFNGEAPRAIVVLRQGEK 548
            ..|..||:.:..:.||..|...|:...:.....:.|..|:|:   .||  |....|.:.:::..:
Human   474 FIYFHDRVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHE--GRIGMASIKMKENHE 536

  Fly   549 ASAEEISAYVAERVAHYKK 567
            ...:::..::|:.:..|.:
Human   537 FDGKKLFQHIADYLPSYAR 555

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	116/539 (22%)
		Firefly_Luc_like	99..587	CDD:213279	112/519 (22%)
SLC27A2	NP_003636.2	hsFATP2a_ACSVL_like	74..610	CDD:341261	112/520 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165148979
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840