DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdgy and sbf2

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	XP_031755557.1	Gene:	sbf2 / 100036675	XenbaseID:	XB-GENE-1004468	Length:	1898	Species:	Xenopus tropicalis

Alignment Length:	541	Identity:	101/541 - (18%)
Similarity:	180/541 - (33%)	Gaps:	174/541 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 HYSPEDG---------YYKTSPFDPV-----TIPNVPLHEYVWRDFKKWERRTAAVCVITDRQYT 104
            |..|.:|         .:|.:|.||:     .|.:||:.. :.|:.|           |..:...
Frog   908 HILPAEGALFLTTYRIIFKGTPHDPLVGEQTVIRSVPIAS-ITREKK-----------INVQNQL 960

  Fly   105 FAQMRDA----SAAFAVRLQTKFNLQ-KPDVLAICLPNLPE--YPIATLG--AIEAGLTVTTVNP 160
            ...|::.    ||.|.: ::..|:.: .|:::.:....|.:  ||::...  |..||   .|..|
Frog   961 HPNMQEGLQIRSATFQL-IKVAFDEEVSPEMVDLFKKQLMKFRYPLSIFSAFAFAAG---QTAPP 1021

  Fly   161 VYTPDEIARQLTF--------SGAKFLVGTVSGFATLSQASKL-VGRQIPIAV------------ 204
            :..|.:..:..:|        .|||             :|.|: :|||.....
Frog  1022 IILPKQKEKNTSFRTISKTIVKGAK-------------RAGKMTIGRQYAAKKKTGTILEERGSR 1073

  Fly   205 --------VRTSAEEALPEGAIDFSELTSTQNVRYEDLKAPKEASADDMVFLPFSSGTTGLPKGV 261
                    :..|.:..||.|.:..||            |:..|...:...|..:.....|
Frog  1074 SGGNEDDDISVSDDNELPSGTLKPSE------------KSTMEQLVERACFRDYQRLALG----- 1121

  Fly   262 MLSHNNITSNCEQVQASLPLDLMGPQNTLPGVLPFFHIYGLTVV-------MLSKLGQGCRLATM 319
            .:|:::.....|..:.:....:.....:.||:|         ||       .|.|:.:..|...:
Frog  1122 TISNSSTRFKSEHFRVTALNRMYSLCRSYPGLL---------VVPQSVQDSSLQKVARCYRHNRL 1177

  Fly   320 PCF-----KPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQETAPHLKVVMSGAAPIGQHDVE 379
            |..     |.:..:.....:.|..:     :.||...:   |...||...:..|.:.     :.|
Frog  1178 PIVSWKNSKTNAMLLRAGGFHGKTV-----VGLFKSQN---THTAAPASSLESSSSI-----EQE 1229

  Fly   380 RFLNKFPNTV---FK-QGYGMTEASPVVLLTPEGNKVYASTGVLPASTEAKIVP--LDG----SD 434
            ::|....|.:   :| .|.|.....|.:.|:| |:...||.   .:|....:||  :||    |.
Frog  1230 KYLQALLNAISVHYKMNGNGTLTVRPTLALSP-GSDRKASR---MSSVVKHVVPSHVDGSLSHSF 1290

  Fly   435 AKGVGPRTTGELCVRGPQVMAGYLNNDEANQVTFYPGNWLRSGDVAFYDEDGLFYITDRMKELIK 499
            |:||                .||.:.       .:|.:..:|..:|..:..|::........||.
Frog  1291 ARGV----------------LGYRDK-------LFPHSNPKSATMARMENPGVWASLRSSNRLIT 1332

  Fly   500 VKGFQVPPAELEAVL--RDHP 518
            .   |.|..::.|.|  :|.|
Frog  1333 T---QTPLIDVGARLVGKDPP 1350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	91/504 (18%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	88/482 (18%)
sbf2	XP_031755557.1	uDENN	1..85	CDD:214824
		DENN	115..297	CDD:396629
		dDENN	351..419	CDD:129037
		SBF2	532..753	CDD:403522
		PH-GRAM_MTMR13	880..998	CDD:275416	19/102 (19%)
		PTP_DSP_cys	1135..1539	CDD:421693	52/268 (19%)
		PH_Sbf1_hMTMR5	1791..1896	CDD:269941
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165168209
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930