DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdgy and zgc:158482

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001076488.1	Gene:	zgc:158482 / 100009650	ZFINID:	ZDB-GENE-070209-32	Length:	619	Species:	Danio rerio

Alignment Length:	580	Identity:	117/580 - (20%)
Similarity:	209/580 - (36%)	Gaps:	126/580 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 FDPVTIPNVPLHEYVWRDFKKWE--RRTAAVCVITDRQYTFAQM-------------------RD 110
            |.|:..|::..|..:.|...::|  ||...|.:..||   |.|.                   ||
Zfish    22 FSPLLWPDLLYHARLLRALLRFESRRRRRPVFLPVDR---FLQQAEARPHKPFIVFEGQTLTYRD 83

  Fly   111 A---SAAFAVRLQTKFNLQKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQL- 171
            |   |...|..|..:..::..|..|:.:.|.|.:.:..:...:.|.....:|.....|.:.|..
Zfish    84 ADRESNRIANALLRECGMRAGDTAALFITNQPAFILCWIALAKLGCACALLNTSIRDDSLIRSFR 148

  Fly   172 TFSGAKFLVGTV---------------SGFATLSQASKLVGRQIPIAVVRTSAEEALPEGAIDFS 221
            ...|||.|:.:.               .|...|....:..|.:......:.|::.|:|  |...:
Zfish   149 CCRGAKVLIASADLQAAVQQVCVPLQQDGVCVLMMGMECSGMRSLSRAAQESSDTAVP--AAVRA 211

  Fly   222 ELTSTQNVRYEDLKAPKEASADDMVFLPFSSGTTGLPKGVMLSHNNITSNCEQVQASLPLDLMGP 286
            .||:.....|                 .::||||||||..:::...:.::.    |.||...:..
Zfish   212 HLTNNTPAVY-----------------IYTSGTTGLPKAAVITQTRLLASL----AVLPSIGVTH 255

  Fly   287 QNTLPGVLPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMIN 351
            .:.|...||.:|..|..:..:..:..|..:.....|....|......::.:::..:..|..::.|
Zfish   256 TDVLYVTLPLYHTAGFLIGFMGCVETGSSMVLRRKFSASRFWDECRAHEVTVVQYIGEILRYLCN 320

  Fly   352 HPKLTQETAPHLKVVMSGAAPIGQHDVER-FLNKFPNTVFKQGYGMTEASPVVLLTPEGNKVYAS 415
            .|:...:....:::.:....   :.||.| ||.:|.....::.|..|          |||..:.:
Zfish   321 TPQRAVDQHHAVRLAIGNGL---RADVWREFLQRFGQMEVREFYAST----------EGNIGFLN 372

  Fly   416 -TGVLPA----------STEAKIVPLDGSDAKGVGPRTTGELCVRGPQVMAGYLNNDEANQVT-- 467
             ||.|.|          :....::..|....:.|  |.:...||..|:...|.|    .:|:|
Zfish   373 YTGRLGAVGRVSFLHRMAVHYALIQFDTEREEPV--RDSSGRCVEVPKGQTGLL----VSQITHM 431

  Fly   468 ---------------------FYPGN-WLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPPAEL 510
                                 |..|: :..|||:...|:|...|..||:.:..:.||..|...|:
Zfish   432 APFVGYAHDEQQTERKRLRDVFRRGDVYFNSGDLMRMDQDNFLYFIDRVGDTFRWKGENVATTEV 496

  Fly   511 EAVLRDHPKILEAAVFGI---PHEFNGEAPRAIVVLRQGEKASAEEISAYVAERVAHYKK 567
            ..||.....:.||:|:|:   .||  |....|.|.|:.|.:...:::..:|:..:..|.:
Zfish   497 SDVLSLLECVAEASVYGVCVPGHE--GRIGMAAVKLKDGAEFEQKQVFEHVSRLLPAYAR 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	114/570 (20%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	108/546 (20%)
zgc:158482	NP_001076488.1	PRK08279	24..619	CDD:236217	116/578 (20%)
zgc:158482	NP_001076488.1	AFD_class_I	76..609	CDD:302604	104/523 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582968
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840