DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pdgy and slc27a2b

DIOPT Version :9

Sequence 1:	NP_001188590.1	Gene:	pdgy / 32426	FlyBaseID:	FBgn0027601	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_001373573.1	Gene:	slc27a2b / 100004228	ZFINID:	ZDB-GENE-081104-49	Length:	616	Species:	Danio rerio

Alignment Length:	562	Identity:	124/562 - (22%)
Similarity:	213/562 - (37%)	Gaps:	107/562 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 YYKTSPFDPVTIPNVPLHEYVWRDFKKWERRTAAVCVITDRQYTFAQMRDASAAFAVRLQTKFNL 125
            |.|:.||  .||.: ...:.|.::.||      |.....|:.|::.|....|...|..|....:|
Zfish    42 YIKSKPF--YTILD-RFQDSVRKNPKK------AFIRFLDQTYSYEQSDKESNKIARTLLKHADL 97

  Fly   126 QKPDVLAICLPNLPEYPIATLGAIEAGLTVTTVNPVYTPDEIARQLTFSGAKFLVGTVSGFATLS 190
            .:.|.:|:.|.|.|.:....||..:.|.:|..:|.......:....|..||..|:
Zfish    98 HEGDTVALLLGNEPMFLWIWLGLAKIGCSVALLNHNIRSKSLLHCFTCCGANVLI---------- 152

  Fly   191 QASKLVGRQIPIAVVRTSAEEALP---EGAIDFSELTS----------TQNVRY-EDLKAPKEAS 241
                 .|..:..||     ||.||   |..|....||.          |..::. .|...|.:..
Zfish   153 -----AGADLQDAV-----EEVLPALREQGISIYILTEHVSSEGMTSLTDKIKQASDQPIPTDLR 207

  Fly   242 ADDMVFLP----FSSGTTGLPKGVMLSHNNITSNCEQVQASLPLDLMGPQNTLPGV--------- 293
            |:.....|    ::||||||||..:::|..:.:             |....::.||
Zfish   208 ANVAFNTPAAYIYTSGTTGLPKAAVITHRRLWA-------------MAFFQSICGVKSDDVIYVC 259

  Fly   294 LPFFHIYGLTVVMLSKLGQGCRLATMPCFKPDDFMRSLDKYQGSILNLVPPIALFMINHPKLTQE 358
            ||.:|..|..:.....:.:|..:.....|....|.....||..:::..:.....::.|.||...:
Zfish   260 LPLYHSSGFGLGFGGSVERGATIVLRSKFSSSQFWDDCRKYNVTVIQYIGETMRYLCNMPKCVSD 324

  Fly   359 TAPHLKVVM-SGAAPIGQHDVER-FLNKFPNTVFKQGYGMTEAS-----------PVVLLTPEGN 410
            ...::::.: :|..|    |:.| |:|:|.:...|:.||.||.:           .|..:.....
Zfish   325 QVHNVRMAIGNGIRP----DIWRTFINRFGHVEIKEFYGSTEGTLGFLNYAGKIGAVGTVNSFHK 385

  Fly   411 KVYASTGVLPASTEAKIVPLDGSD------AKGVGPRTTGELCVRGPQVM--AGYLNNDEANQV- 466
            |:|..  |.......|..|:..:|      |||    .||.|..|..|.:  :||..:.:..:.
Zfish   386 KLYPY--VFIKFDHEKEEPVRNADGFCIEVAKG----ETGLLVTRLTQKIEFSGYARDPKQTEKK 444

  Fly   467 ----TFYPGN-WLRSGDVAFYDEDGLFYITDRMKELIKVKGFQVPPAELEAVLRDHPKILEAAVF 526
                .|..|: :..:||:...|.:...|..||:.:..:.||..|...|:..::...|.|.||.|:
Zfish   445 KLHDVFEKGDVYFNTGDLFRTDRENFIYFQDRVGDTFRWKGENVSTNEVSDIMTLVPCIEEANVY 509

  Fly   527 GIP-HEFNGEAPRAIVVLRQGEKASAEEISAYVAERVAHYKK 567
            |:. ..|.|....|.::|::..:...:::..:|...:..|.:
Zfish   510 GVTVPGFEGRIGMAAIILKKDHQFECDDVFNHVTSYLPVYAR 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pdgy	NP_001188590.1	CaiC	77..595	CDD:223395	118/546 (22%)
pdgy	NP_001188590.1	Firefly_Luc_like	99..587	CDD:213279	114/524 (22%)
slc27a2b	NP_001373573.1	hsFATP2a_ACSVL_like	70..606	CDD:341261	114/525 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582967
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840