DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Flo2 and AT5G25260

DIOPT Version :9

Sequence 1:	NP_001259553.1	Gene:	Flo2 / 32425	FlyBaseID:	FBgn0264078	Length:	448	Species:	Drosophila melanogaster
Sequence 2:	NP_197908.1	Gene:	AT5G25260 / 832597	AraportID:	AT5G25260	Length:	463	Species:	Arabidopsis thaliana

Alignment Length:	478	Identity:	101/478 - (21%)
Similarity:	176/478 - (36%)	Gaps:	124/478 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 MCENVETSQGVPLTVTGVAQCKIMKSS---SYKQTDYHNDEMMNVYYFHHQ---ADELLGTASEQ 113
            |.:....||.:.:|..|:...|:.|.|   .:::....:...:| |.|..|   |::|.......
plant     1 MFKVARASQYLAITGGGIEDIKLSKKSWVFPWQRCTVFDVSPVN-YTFKVQAMSAEKLPFVLPAV 64

  Fly   114 F-LGKSVKEIKQTILQ--------------------TLEGHLRAILGTLTVEEVYKDRDQFAALV 157
            | :|..|.:.:..||.                    .:||..|.:..::|:||::|...:|...|
plant    65 FTIGPRVDDTEALILYARLISPHDKQSNHVNELVEGVIEGETRVLAASMTMEEIFKGTKEFKKEV 129

  Fly   158 REVAAPDVGRMGIEILSFTIKDVYD--DVQYLASLGKAQTAVVKRDADAGVAEANR--DAGIRE- 217
            .:....::.:.|:.|.:..:|.:.|  ..:|.:.||:.........|...||||..  :.|.:|
plant   130 FDKVQLELDQFGLVIYNANVKQLVDVPGHEYFSYLGQKTQMEAANQARIDVAEAKMKGEIGAKER 194

  Fly   218 ------------AEC---------EKSAMDVKYSTDTKIEDNTRMYKLQKANFDQEINTAKAESQ 261
                        ||.         |.:..::|..|:.|:.:|           .:|.:.|||.|:
plant   195 TGLTLQNAAKIDAESKIISMQRQGEGTKAEIKVKTEVKVFEN-----------QKEADVAKANSE 248

  Fly   262 LAYELQAAKIRQRIRNEEIQIEVVERRKQIEIESQEVQ---RKDRELTGTVKLPAEAEAFRLQTL 323
            ||       :::....::.::..||..|.:.:...|:|   .|...||.|.||.||       .|
plant   249 LA-------MKKAAWTKDAKVAEVEATKAVALREAELQTQVEKMNALTRTEKLKAE-------FL 299

  Fly   324 AQAKQCQTIEGARAEAERIRKIGSAEAHAIELVGKAEAERMRMKAHVYKQYGDA----------- 377
            ::|......:...|..|...|...|||...|...:|||::....|..|.:..:|
plant   300 SKASVEYETKVQEANWELYNKQKQAEAVLYEKQKQAEAQKAEADATFYSKQKEAEGLVALASAQG 364

  Fly   378 --------AIMN--IVLESLPKIAAEVAAPLAKTDEIVL-----------------IGG-NDNIT 414
                    |:.|  ..|.....|.......:|||:.:.:                 ||| :.:..
plant   365 TYLRTLLDAVQNDYSCLRDFLMINNGTYQEIAKTNALAVRDLQPKISVWNHGGEQGIGGASGSGM 429

  Fly   415 NDVTRLVAQLPPSINAL---TGV 434
            .|:..|...|||.::.:   ||:
plant   430 KDIAGLYKMLPPVLDTVYEQTGM 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Flo2	NP_001259553.1	SPFH_flotillin	34..201	CDD:259798	35/174 (20%)
		PHB	110..281	CDD:214581	42/217 (19%)
		SPFH_like	<286..374	CDD:302763	26/90 (29%)
		Flot	337..>410	CDD:292597	23/111 (21%)
AT5G25260	NP_197908.1	SPFH_flotillin	28..175	CDD:259798	27/147 (18%)
AT5G25260	NP_197908.1	ATP-synt_B	<258..341	CDD:304375	25/89 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	61	1.000	Domainoid score	I3805
eggNOG	1	0.900	-	-		E1_COG2268
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	101	1.000	Inparanoid score	I2168
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D812555at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.870