Protein Alignment Flo2 and Flot2

DIOPT Version :9

• Sequence 1: NP_001259553.1
• Gene: Flo2 / 32425
• FlyBaseID: FBgn0264078
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_001271156.1
• Gene: Flot2 / 14252
• MGIID: 103309
• Length: 456
• Species: Mus musculus
• Alignment Length: 478
• Identity: 277/478 - (57%)
• Similarity: 349/478 - (73%)
• Gaps: 54/478 - (11%)

  Fly     1 MGNIHTTGPNEALIVSGGCCGSTKKRTIVGGWAWAWWLVTDVQRL-------------------- 45
            |||.||.||||||:||||||||..|:.:.||||||||.::|.|.|
Mouse     1 MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQSLRLCWPGWVEILRAPHRAAVY 65

  Fly    46 --------SLNVMTLNPMCENVETSQGVPLTVTGVAQCKIMKSSSYKQTDYHNDEMMNVYYFHHQ 102
                    ||.:|||.|.||:|||::||.||||||||.|||...
Mouse    66 QASVLIWISLEIMTLQPRCEDVETAEGVALTVTGVAQVKIMTEK--------------------- 109

  Fly   103 ADELLGTASEQFLGKSVKEIKQTILQTLEGHLRAILGTLTVEEVYKDRDQFAALVREVAAPDVGR 167
              |||..|.||||||:|::||..:|||||||||:||||||||::|:||||||.||||||||||||
Mouse   110 --ELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGR 172

  Fly   168 MGIEILSFTIKDVYDDVQYLASLGKAQTAVVKRDADAGVAEANRDAGIREAECEKSAMDVKYSTD 232
            |||||||||||||||.|.||:||||.|||||:||||.|||||.||||||||||:|..:|||:..|
Mouse   173 MGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAEAERDAGIREAECKKEMLDVKFMAD 237

  Fly   233 TKIEDNTRMYKLQKANFDQEINTAKAESQLAYELQAAKIRQRIRNEEIQIEVVERRKQIEIESQE 297
            |||.|:.|.::|||:.|.:|:|...||:|||||||.|:.:|:||.|||:||||:|:|||.:|:||
Mouse   238 TKIADSKRAFELQKSAFSEEVNIKTAEAQLAYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQE 302

  Fly   298 VQRKDRELTGTVKLPAEAEAFRLQTLAQAKQCQTIEGARAEAERIRKIGSAEAHAIELVGKAEAE 362
            :.|.|:||..||:.||||||.|:|.:|:.::.:.:..|:||||:|||||.|||..||.:||||||
Mouse   303 ILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAE 367

  Fly   363 RMRMKAHVYKQYGDAAIMNIVLESLPKIAAEVAAPLAKTDEIVLIGG-NDNITNDVTRLVAQLPP 426
            ||::||..|::|||||.|.:|||:||:|||:::|||.|.||||::.| |..:|::|.||:|:||.
Mouse   368 RMKLKAEAYQKYGDAAKMALVLEALPQIAAKISAPLTKVDEIVVLSGDNSKVTSEVNRLLAELPA 432

  Fly   427 SINALTGVDLSKV--LSKIPGAK 447
            |::|||||||||:  :....||:
Mouse   433 SVHALTGVDLSKIPLIKNATGAQ 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Flo2	NP_001259553.1	SPFH_flotillin	34..201	CDD:259798	107/194 (55%)
		PHB	110..281	CDD:214581	123/170 (72%)
		SPFH_like	<286..374	CDD:302763	48/87 (55%)
		Flot	337..>410	CDD:292597	48/73 (66%)
Flot2	NP_001271156.1	SPFH_flotillin	72..206	CDD:259798	100/156 (64%)
		PHB	115..297	CDD:214581	131/181 (72%)
		Flot	341..>415	CDD:292597	47/73 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167850262
Domainoid	1	1.000	275	1.000	Domainoid score	I1747
eggNOG	1	0.900	-	-		E1_COG2268
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3293
Inparanoid	1	1.050	550	1.000	Inparanoid score	I1132
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52449
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001627
OrthoInspector	1	1.000	-	-		oto92468
orthoMCL	1	0.900	-	-		OOG6_106546
Panther	1	1.100	-	-	LDO	PTHR13806
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4918
SonicParanoid	1	1.000	-	-		X5086
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790