Protein Alignment Flo2 and Flot2

DIOPT Version :10

• Sequence 1: NP_001259553.1
• Gene: Flo2 / 32425
• FlyBaseID: FBgn0264078
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_001271156.1
• Gene: Flot2 / 14252
• MGIID: 103309
• Length: 456
• Species: Mus musculus
• Alignment Length: 478
• Identity: 277/478 - (57%)
• Similarity: 349/478 - (73%)
• Gaps: 54/478 - (11%)

  Fly     1 MGNIHTTGPNEALIVSGGCCGSTKKRTIVGGWAWAWWLVTDVQRL-------------------- 45
            |||.||.||||||:||||||||..|:.:.||||||||.::|.|.|
Mouse     1 MGNCHTVGPNEALVVSGGCCGSDYKQYVFGGWAWAWWCISDTQSLRLCWPGWVEILRAPHRAAVY 65

  Fly    46 --------SLNVMTLNPMCENVETSQGVPLTVTGVAQCKIMKSSSYKQTDYHNDEMMNVYYFHHQ 102
                    ||.:|||.|.||:|||::||.||||||||.|||...
Mouse    66 QASVLIWISLEIMTLQPRCEDVETAEGVALTVTGVAQVKIMTEK--------------------- 109

  Fly   103 ADELLGTASEQFLGKSVKEIKQTILQTLEGHLRAILGTLTVEEVYKDRDQFAALVREVAAPDVGR 167
              |||..|.||||||:|::||..:|||||||||:||||||||::|:||||||.||||||||||||
Mouse   110 --ELLAVACEQFLGKNVQDIKNVVLQTLEGHLRSILGTLTVEQIYQDRDQFAKLVREVAAPDVGR 172

  Fly   168 MGIEILSFTIKDVYDDVQYLASLGKAQTAVVKRDADAGVAEANRDAGIREAECEKSAMDVKYSTD 232
            |||||||||||||||.|.||:||||.|||||:||||.|||||.||||||||||:|..:|||:..|
Mouse   173 MGIEILSFTIKDVYDKVDYLSSLGKTQTAVVQRDADIGVAEAERDAGIREAECKKEMLDVKFMAD 237

  Fly   233 TKIEDNTRMYKLQKANFDQEINTAKAESQLAYELQAAKIRQRIRNEEIQIEVVERRKQIEIESQE 297
            |||.|:.|.::|||:.|.:|:|...||:|||||||.|:.:|:||.|||:||||:|:|||.:|:||
Mouse   238 TKIADSKRAFELQKSAFSEEVNIKTAEAQLAYELQGAREQQKIRQEEIEIEVVQRKKQIAVEAQE 302

  Fly   298 VQRKDRELTGTVKLPAEAEAFRLQTLAQAKQCQTIEGARAEAERIRKIGSAEAHAIELVGKAEAE 362
            :.|.|:||..||:.||||||.|:|.:|:.::.:.:..|:||||:|||||.|||..||.:||||||
Mouse   303 ILRTDKELIATVRRPAEAEAHRIQQIAEGEKVKQVLLAQAEAEKIRKIGEAEAAVIEAMGKAEAE 367

  Fly   363 RMRMKAHVYKQYGDAAIMNIVLESLPKIAAEVAAPLAKTDEIVLIGG-NDNITNDVTRLVAQLPP 426
            ||::||..|::|||||.|.:|||:||:|||:::|||.|.||||::.| |..:|::|.||:|:||.
Mouse   368 RMKLKAEAYQKYGDAAKMALVLEALPQIAAKISAPLTKVDEIVVLSGDNSKVTSEVNRLLAELPA 432

  Fly   427 SINALTGVDLSKV--LSKIPGAK 447
            |::|||||||||:  :....||:
Mouse   433 SVHALTGVDLSKIPLIKNATGAQ 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Flo2	NP_001259553.1	YqiK	5..448	CDD:441869	274/474 (58%)
Flot2	NP_001271156.1	YqiK	5..455	CDD:441869	273/472 (58%)