Protein Alignment Flo2 and Flot1

DIOPT Version :9

• Sequence 1: NP_001259553.1
• Gene: Flo2 / 32425
• FlyBaseID: FBgn0264078
• Length: 448
• Species: Drosophila melanogaster
• Sequence 2: NP_032053.1
• Gene: Flot1 / 14251
• MGIID: 1100500
• Length: 428
• Species: Mus musculus
• Alignment Length: 440
• Identity: 185/440 - (42%)
• Similarity: 281/440 - (63%)
• Gaps: 30/440 - (6%)

  Fly     6 TTGPNEALIVSGGCCGSTKKRTIVGGWAWAWWLVTDVQRLSLNVMTLNPMCENVETSQGVPLTVT 70
            |.|||||::|||.|  .:....:.||..:....:..:||:|||.:|||...|.|.|..|||::||
Mouse     4 TCGPNEAMVVSGFC--RSPPVMVAGGRVFVLPCIQQIQRISLNTLTLNVKSEKVYTRHGVPISVT 66

  Fly    71 GVAQCKIMKSSSYKQTDYHNDEMMNVYYFHHQADELLGTASEQFLGKSVKEIKQTILQTLEGHLR 135
            |:||.||                      ..|..|:|..|.:.||||:..||....|:|||||.|
Mouse    67 GIAQVKI----------------------QGQNKEMLAAACQMFLGKTEAEIAHIALETLEGHQR 109

  Fly   136 AILGTLTVEEVYKDRDQFAALVREVAAPDVGRMGIEILSFTIKDVYDDVQYLASLGKAQTAVVKR 200
            ||:..:||||:||||.:|:..|.:||:.|:..|||.::|:|:||::||..||.|||||:||.|::
Mouse   110 AIMAHMTVEEIYKDRQKFSEQVFKVASSDLVNMGISVVSYTLKDIHDDQDYLHSLGKARTAQVQK 174

  Fly   201 DADAGVAEANRDAGIREAECEKSAMDVKYSTDTKIEDNTRMYKLQKANFDQEINTAKAESQLAYE 265
            ||..|.|||.||||||||:.::..:..:..::.::....|.|:|:||.:|.|:||.:|::.|||:
Mouse   175 DARIGEAEAKRDAGIREAKAKQEKVSAQCLSEIEMAKAQRDYELKKATYDIEVNTRRAQADLAYQ 239

  Fly   266 LQAAKIRQRIRNEEIQIEVVERRKQIEIESQEVQRKDRELTGTVKLPAEAEAFRLQTLAQAKQCQ 330
            ||.||.:|:|..:.:|::||||.:|:.::.||:.|:::||...|:.|||||.:||:.||:|::.|
Mouse   240 LQVAKTKQQIEEQRVQVQVVERAQQVAVQEQEIARREKELEARVRKPAEAERYRLERLAEAEKAQ 304

  Fly   331 TIEGARAEAERIRKIGSAEAHAIELVGKAEAERMRMKAHVYKQYGDAAIMNIVLESLPKIAAEVA 395
            .|..|.||||.:|..|.|||.||....:||||:|..||..::.|.:||.::::||.||::|.|::
Mouse   305 LIMQAEAEAESVRMRGEAEAFAIGARARAEAEQMAKKAEAFQMYQEAAQLDMLLEKLPQVAEEIS 369

  Fly   396 APLAKTDEIVLIG------GNDNITNDVTRLVAQLPPSINALTGVDLSKV 439
            .||...::|.|:.      |...:|.:|..::::||.|:..||||.:|:|
Mouse   370 GPLTSANKITLVSSGSGTMGAAKVTGEVLDILSRLPESVERLTGVSISQV 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Flo2	NP_001259553.1	SPFH_flotillin	34..201	CDD:259798	72/166 (43%)
		PHB	110..281	CDD:214581	81/170 (48%)
		SPFH_like	<286..374	CDD:302763	40/87 (46%)
		Flot	337..>410	CDD:292597	31/78 (40%)
Flot1	NP_032053.1	YqiK	4..424	CDD:225177	185/440 (42%)
		SPFH_flotillin	30..175	CDD:259798	72/166 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2268
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4089
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D340567at33208
OrthoFinder	1	1.000	-	-		FOG0001627
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.770