DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9503 and CG6142

DIOPT Version :9

Sequence 1:	NP_572987.1	Gene:	CG9503 / 32424	FlyBaseID:	FBgn0030598	Length:	626	Species:	Drosophila melanogaster
Sequence 2:	NP_651466.1	Gene:	CG6142 / 43178	FlyBaseID:	FBgn0039415	Length:	616	Species:	Drosophila melanogaster

Alignment Length:	564	Identity:	274/564 - (48%)
Similarity:	386/564 - (68%)	Gaps:	1/564 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 LDHYDFIVIGAGSAGAVVANRLTEVENWNVLLLEAGGDETELTDVPLMAGYLQLSKIDWQYKTEP 121
            |..||||::||||||.|:||||:|:.:.:|||||||..||.::||||.|...|:::.:|.||.||
  Fly    45 LPEYDFIIVGAGSAGCVMANRLSEISSASVLLLEAGDQETFISDVPLTAALTQMTRYNWGYKAEP 109

  Fly   122 SGTSCLAMQGGRCNWPRGKVLGGSSVLNYMLYLRGSKHDYDNWEAMGNPSWSYRDALYYFKKSED 186
            :..:|..::||.||||:|:.:||:|::|:|||.||.:.|||.|.|..|..|||.:.|.||:|||.
  Fly   110 TEHACQGLKGGVCNWPKGRGVGGTSLINFMLYTRGHRRDYDEWAAANNSGWSYDELLPYFRKSER 174

  Fly   187 NTNQYLANTPYHATGGYLTVGEAPYHTPLAASFVEAGVEMGYENRDLNGEKMTGFMIAQGTTRRG 251
            .....|..:|||...|.|.|....|.:.|..:|:::|.|||||..|.|||.:.||..:|.|.|.|
  Fly   175 IGIPELYKSPYHGRNGQLDVQYTDYRSQLLKAFLKSGREMGYEITDPNGEHLMGFARSQATIRNG 239

  Fly   252 SRCSTSKAFLRPARLRPNLHISMNSHVTRIMIDPVTKLAFGVEFVKDQKLYHVRATKEVVLSGGS 316
            .||||||||::|...|.||||||.|.|||::|||:||.|.||||||.::.|.|||.|||:||.|:
  Fly   240 RRCSTSKAFIQPVVNRKNLHISMKSWVTRLIIDPITKTATGVEFVKQRQRYVVRARKEVILSAGT 304

  Fly   317 VNSPQLLMLSGVGPRKELAKHRIPLIKELSVGENLQDHIGLGGLTFLVNQPVSIVENRFHTMSTV 381
            :.|||||||||:||.:.|.:|.|.::::|.||.||||||.|.||.|:||.. ::.:.|....|.:
  Fly   305 IASPQLLMLSGIGPAEHLREHNITVMQDLPVGYNLQDHITLNGLVFVVNDS-TVNDARLLNPSDI 368

  Fly   382 LQYAVFGQGPLTILGGVEGLAYVNTKYANSSLDWPDIEFHFVSGSTNSDGGSQLRKAHGLTDAFY 446
            .:|...||||.||.||.|..|:|.|..:..:.|:||:|....:||.:.|....:|...|:||.||
  Fly   369 FRYIFAGQGPYTIPGGAEAFAFVRTPSSKFAKDYPDMELVLGAGSLSGDRFGTMRNLLGITDEFY 433

  Fly   447 RAVFEPINNRDAWSIIPMLLRPRSVGNIRLRSGNPFDYPYIFPNYLTDDFDMKTLIEGVKIAVAL 511
            ..:|..:.:::.:.::|:||||:|.|.|.|||.|||.:|.:.||::....|::.:|||:::.:.|
  Fly   434 DYMFGDLQSKETFGLVPVLLRPKSRGRISLRSRNPFHWPRMEPNFMQHPDDVRAMIEGIEMILKL 498

  Fly   512 SRTKAMQRFGSRISSIRWPGCEQVPLFTDAFWECMVRRYTSTIYHPVGTCKMGPYWDKDAVVDAK 576
            ||:|.|.:.|:|.....:||||.:...::|:|:|.:|||.|::.|..|||||||..|..:||||:
  Fly   499 SRSKPMAKMGTRFHDRPFPGCENLKFASEAYWKCCLRRYGSSLQHQSGTCKMGPATDNTSVVDAQ 563

  Fly   577 LRVYGIRGLRVIDASIMPKLVSANTNAPVIMIAEKGSDMIKEFW 620
            ||::|||||||:|||::|.:.:.:|||.|||:|||..||||:.|
  Fly   564 LRIHGIRGLRVVDASVLPNVPAGHTNAIVIMVAEKAGDMIKDAW 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9503	NP_572987.1	PRK02106	59..617	CDD:235000	270/557 (48%)
		NADB_Rossmann	122..354	CDD:304358	120/231 (52%)
		GMC_oxred_C	468..611	CDD:282984	68/142 (48%)
CG6142	NP_651466.1	PRK02106	47..604	CDD:235000	270/557 (48%)
		NADB_Rossmann	48..342	CDD:304358	156/293 (53%)
		GMC_oxred_C	455..599	CDD:282984	69/143 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm24368
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11552
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
	8	8.060