Protein Alignment Eo and Chdh

DIOPT Version :9

• Sequence 1: NP_572986.1
• Gene: Eo / 32423
• FlyBaseID: FBgn0030597
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_001129712.1
• Gene: Chdh / 218865
• MGIID: 1860776
• Length: 596
• Species: Mus musculus
• Alignment Length: 632
• Identity: 196/632 - (31%)
• Similarity: 275/632 - (43%)
• Gaps: 126/632 - (19%)

  Fly    73 AWPLQHE--PPEDR----LEIESYDYIVVGAGSAGSIVASRLSELCQVKVLLLEEGQLPPLESEI 131
            ||.:|.:  ||..|    :..:.|.::||||||||.::||||:|....:|||||.|.    :..:
Mouse    20 AWAVQGQPCPPCSRAVASVGKDEYTFVVVGAGSAGCVLASRLTEDPNHRVLLLEAGP----KDLL 80

  Fly   132 FG---LTGALHH---------DERYMFLEEAVPNPKCCQAMASMHGCV--WWHGRMMGGGGAING 182
            .|   |...:|.         |::|.:.....|.|       .|...|  |..||:.||..::|.
Mouse    81 MGSKRLQWKIHMPAALVSNLCDDKYNWYYHTEPQP-------GMDSRVLYWPRGRVWGGSSSLNA 138

  Fly   183 NIFIPGSRENFRRWN---STGWDWTQVHKTYSRLQQRLNPSYLQPNKLNLKLANLIYSGSAELGV 244
            .::|.|..|::.||:   :.|||:... ..|.|..||        ::|.   ||:...|...|.|
Mouse   139 MVYIRGHAEDYNRWHREGAEGWDYAHC-LPYFRKAQR--------HELG---ANMYRGGDGPLHV 191

  Fly   245 PRMK--QPL---------IAGATF-----GYTHH----VPVTVNQRRRASSARLYLANDQVNRRG 289
            .|.|  .||         .||..|     |:...    :.:||:|.:|.|:|..||  ..|..|.
Mouse   192 SRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGWMDMTVHQGKRWSTACAYL--HPVLSRP 254

  Fly   290 NLKVIRGAQVQRVLLNAAGSRATGVIYTLNGVEHTAKTLGEVILSAGTLNSAKLLLLSGIGPREE 354
            ||:......|.|||..  |:||.||.|..:|..|.|....|||||.|.:||.:||:|||:|..::
Mouse   255 NLRAEVQTLVSRVLFE--GTRAVGVEYIKDGQRHKAYVSREVILSGGAINSPQLLMLSGVGNADD 317

  Fly   355 LQRWNITTHQDLP-VGRNLQDHGMMPLFLLFGSNCAVNSTRDPTENPYAPVSI-----TQYLLDN 413
            |::.:|.....|| ||:|||||    |.:.....|....|....:.|...|.|     ..|..|.
Mouse   318 LRKLDIPVVCHLPGVGQNLQDH----LEVYVQQACTQPITLHSAQKPLRKVCIGLEWLWSYTGDG 378

  Fly   414 QKGPLASGFYMMGYINSSSPSSSRGEPDLHVVAHTLLPKGSTGSFGYLGFRPELIQAQQDILQKG 478
            ....|.:|    |:|. |.|.....:...|.:...::..|.         :|    .||
Mouse   379 ATAHLETG----GFIR-SRPGVPHPDIQFHFLPSQVIDHGR---------KP----TQQ------ 419

  Fly   479 DLLQIMGSLLRPLSHGKVSLSSKNSADQAKIENHYGEA---VEDQQTLLRYVRYIQKLSKTRPFR 540
            :..|:....:|..|.|.:.|.|.|..|...|..:|...   |||.:..:|..|.|.......|||
Mouse   420 EAYQVHVGTMRATSVGWLKLRSANPRDHPVIHPNYLSTETDVEDFRQCVRLSREIFAQEALAPFR 484

  Fly   541 RCGLRLWKPPLHECDTLAADSDDYWLCYIRYFYVGAWHSVGTCRMAPRKGVDSQENGGVVDERLR 605
              |..| :|..|      ..||.....::|.....|:|...||:|.     .|.:...|||.:.:
Mouse   485 --GKEL-QPGSH------VQSDKEIDAFVRAKADSAYHPSCTCKMG-----RSSDPTAVVDAQTK 535

  Fly   606 VHGVKGLRVVDASIMPELPAGNTNGPAMMIGEKGAQMI-----LDDR 647
            |.||:.||||||||||.:.:||.|.|.:||.||.|.:|     |:|:
Mouse   536 VIGVENLRVVDASIMPSVVSGNLNAPTVMIAEKAADIIKGHPALEDK 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eo	NP_572986.1	BetA	88..649	CDD:225186	190/611 (31%)
		NADB_Rossmann	185..375	CDD:304358	74/213 (35%)
		GMC_oxred_C	490..638	CDD:282984	52/150 (35%)
Chdh	NP_001129712.1	PRK02106	42..588	CDD:235000	190/610 (31%)
		NAD_binding_8	47..>76	CDD:290186	18/28 (64%)
		GMC_oxred_N	118..341	CDD:279121	83/242 (34%)
		GMC_oxred_C	432..569	CDD:282984	53/150 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.780