Protein Alignment Eo and chdh-1

DIOPT Version :9

• Sequence 1: NP_572986.1
• Gene: Eo / 32423
• FlyBaseID: FBgn0030597
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: NP_495846.1
• Gene: chdh-1 / 174390
• WormBaseID: WBGene00007917
• Length: 599
• Species: Caenorhabditis elegans
• Alignment Length: 620
• Identity: 154/620 - (24%)
• Similarity: 263/620 - (42%)
• Gaps: 126/620 - (20%)

  Fly    92 YIVVGAGSAGSIVASRLSELCQVKVLLLEEGQLPPLESEIFGLTGALHHDERYMFLEEAVPNPKC 156
            :|:|||||||.::|:||:|....:|||:|.|   |::.:   ....:|.....|:        ..
 Worm    40 HIIVGAGSAGCVLANRLTEDPSNRVLLIEAG---PVDHK---WDWRIHMPAALMY--------NL 90

  Fly   157 CQAMASMH------------GCVWWHGRMMGGGGAINGNIFIPGSRENFRRW---NSTGWDWT-- 204
            |....:.|            ...|..||:.||...:|...::.|...::.||   .::||::.
 Worm    91 CSDTYNWHYHTTAQKNLGNRVFYWPRGRVWGGSSTLNAMCYVRGHAYDYNRWEKEGASGWNYANC 155

  Fly   205 ----QVHKTYSRLQQRLNPSYLQPNKLNLKLANLIYSGSAE-------LGVPRMKQPLIAGATFG 258
                :..:|||......:|.......|.:|      .|.||       |.|.: :.||      |
 Worm   156 LPYFKKAETYSDATGPNDPYRGNNGPLYVK------KGDAENPLHKAWLNVGK-EHPL------G 207

  Fly   259 YTHH-----------VPVTVNQRRRASSARLYLANDQVNRRGNLKVIRGAQVQRVLLNAAGSRAT 312
            :|:.           :.:|::...|.|:::.|:  ..:..|.||....|....|||.:.  ::|.
 Worm   208 WTNDMNGEKQEGISTMDMTIHNGERWSASKAYV--HPIRNRPNLITSSGITCTRVLFDT--NKAI 268

  Fly   313 GV--IYTLNGV------EHTAKTL---GEVILSAGTLNSAKLLLLSGIGPREELQRWNITTHQDL 366
            |:  |..||.|      .::.:.:   |:|||:.|.:|:.:||:|||:||.:.|:...|....:|
 Worm   269 GIEFIRKLNFVGTDSIDSYSREKIYCQGDVILAGGAINTPQLLMLSGVGPADHLRSHEIPIVANL 333

  Fly   367 P-VGRNLQDHGMMPLFLLFGSNCAVN-STRDPTENPYAPVSITQYLLDNQKGPLASGFYMMGYIN 429
            | ||:|||||  :.:::...|...|. ..:...:.|:..:.|......|:.|..||.....|...
 Worm   334 PGVGQNLQDH--LEIYVQQESTQPVTLYNKSSWKFPHNMIKIGLEWFTNRTGLGASSHLETGGFA 396

  Fly   430 SSSPSSSRGEPDLHVVAHTLLPKGSTGS--FGYLGFRPELIQAQQDILQKGDLLQIMGSLLRPLS 492
            .|..:.:..:...|.:..|:...|.|..  .||                     |:....:|..|
 Worm   397 RSDDTVTHPDIQFHFLPSTVHDDGRTNGTCHGY---------------------QVHVGPMRSQS 440

  Fly   493 HGKVSLSSKNSADQAKIENHYGEAVEDQQTLLRYVRYIQKLSKTRPFRRC-GLRLWKPPLHECDT 556
            .|.:.|.:|:......|..:|.|...|.:...:.:|..::|..::.|... |..|...|  :|.:
 Worm   441 KGYIMLQAKDPRRAPIINPNYMEEDSDWREFRKCIRVSRELFASKAFDEFRGKELAPGP--DCQS 503

  Fly   557 LAADSDDYWLCYIRYFYVGAWHSVGTCRMAPRKGVDSQENGGVVDERLRVHGVKGLRVVDASIMP 621
             .||.|.    :::.....|:|...||:|    |.::.:...|..|.:.|:|.:.|:|||||:||
 Worm   504 -DADIDR----FVKEKAASAYHPSCTCKM----GSENDKMAVVNPETMGVYGTENLKVVDASVMP 559

  Fly   622 ELPAGNTNGPAMMIGEKGAQMI------LDDREAN 650
            .:.:||.|.|.:|:.|:.|.:|      |...:||
 Worm   560 SIVSGNLNAPVIMMAERAADLIKHKKQLLPPSDAN 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eo	NP_572986.1	BetA	88..649	CDD:225186	152/617 (25%)
		NADB_Rossmann	185..375	CDD:304358	59/228 (26%)
		GMC_oxred_C	490..638	CDD:282984	41/148 (28%)
chdh-1	NP_495846.1	PRK02106	41..599	CDD:235000	154/619 (25%)
		NADB_Rossmann	41..>78	CDD:304358	18/42 (43%)
		NADB_Rossmann	108..345	CDD:304358	67/255 (26%)
		GMC_oxred_C	439..577	CDD:282984	42/148 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I4696
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.790