Protein Alignment Eo and chdh

DIOPT Version :9

• Sequence 1: NP_572986.1
• Gene: Eo / 32423
• FlyBaseID: FBgn0030597
• Length: 657
• Species: Drosophila melanogaster
• Sequence 2: XP_002663301.2
• Gene: chdh / 100331020
• ZFINID: ZDB-GENE-120111-1
• Length: 585
• Species: Danio rerio
• Alignment Length: 629
• Identity: 187/629 - (29%)
• Similarity: 268/629 - (42%)
• Gaps: 108/629 - (17%)

  Fly    59 IALNASSLALANNTAWPLQHEPPEDRL---EIESYDYIVVGAGSAGSIVASRLSELCQVKVLLLE 120
            :|..:||..|.::...||.|......:   ...||.|::|||||||.::||||:|.....|||||
Zfish     1 MACFSSSTRLMSSLCSPLLHHRYISTVVNKNTPSYSYVIVGAGSAGCVLASRLTENPSDSVLLLE 65

  Fly   121 EGQLPPLESEI--------FGLTGALHH---DERYMFLEEAVPNPKCCQAMASMHGCVWWHGRMM 174
            .|   |.:..:        ..:..||.:   |:||.:....:|     ||........|..||:.
Zfish    66 AG---PKDKHLGSTRLSWKIHMPAALTYNLCDDRYNWFYHTLP-----QAHMDDRVMYWPRGRVW 122

  Fly   175 GGGGAINGNIFIPGSRENFRRWNSTGWD-WTQVH-KTYSRLQQRLNPSYLQPNKLNLKLANLIYS 237
            ||..::|..::|.|..|::.||.|.|.| |...| ..|.|..|   ...|.|::..        .
Zfish   123 GGSSSLNAMVYIRGHAEDYNRWQSEGADGWNYDHCLPYFRKAQ---THELGPDRYR--------G 176

  Fly   238 GSAELGVPRMK--QPL-----IAGATFGYTH-------------HVPVTVNQRRRASSARLYLAN 282
            |...|.|.|.|  .||     .||...||.:             .:.:|:::.:|.|:|..||.
Zfish   177 GDGPLHVSRGKTQNPLHYAFIQAGQQAGYPYTEDMNGFQQEGVGWMDMTIHKGQRWSTASAYLR- 240

  Fly   283 DQVNRRGNLKVIRGAQVQRVLLNAAGSRATGVIYTLNGVEHTAKTLGEVILSAGTLNSAKLLLLS 347
             ....|.||.......|.|||.:  |:||.||.|..||.........|||||.|.:||.:|||||
Zfish   241 -PALSRPNLSTEVRCMVTRVLFD--GARARGVEYQQNGQIKKVFAEKEVILSGGAINSPQLLLLS 302

  Fly   348 GIGPREELQRWNITTHQDLP-VGRNLQDHGMMPLFLLFGSNCAVNSTRDPTENPYAPVSI-TQYL 410
            |:|..:||:..:|...|.|| ||.|||||    |.|.....|....|....:.|...:.| .::|
Zfish   303 GVGNADELKTLDIPVVQHLPGVGCNLQDH----LELYVQHACTQPITLYRAQKPLQMLKIGLEWL 363

  Fly   411 LDNQKGPLASGFYMMGYINSSSPSSSRGE---PDL--HVVAHTLLPKGSTGSFGYLGFRPELIQA 470
            |.      .:|:....::.|.....||.:   ||:  |.:...::..|...|
Zfish   364 LK------FTGYGATAHLESGGFIRSRPDVPHPDIQFHFLPSQVIDHGRVSS------------- 409

  Fly   471 QQDILQKGDLLQIMGSLLRPLSHGKVSLSSKNSADQAKIENHYGEAVEDQQTLLRYVRYIQKLSK 535
                  |.:..|:....:|..|.|.:.|.||:..|...::.:|.....|.......||..:::..
Zfish   410 ------KIEAFQVHVGPMRSTSVGWLKLKSKDPRDHPILQPNYLSTETDVLEFRECVRLTREIFA 468

  Fly   536 TRPFRRC-GLRLWKPPLHECDTLAADSDDYWLCYIRYFYVGAWHSVGTCRMAPRKGVDSQENGGV 599
            .:.|... |..:...|..:.|   |:.|    .::|.....|:|...||:|.     ..::...|
Zfish   469 QQAFDEFRGPEVQPGPAVQSD---AEID----AFVRQKADSAYHPSCTCKMG-----RPEDRMAV 521

  Fly   600 VDERLRVHGVKGLRVVDASIMPELPAGNTNGPAMMIGEKGAQMI 643
            |...|||.||:||||||||:||.:.:||.|.|.:||.||.|..|
Zfish   522 VSPELRVFGVEGLRVVDASVMPSMVSGNLNAPTIMIAEKAADAI 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Eo	NP_572986.1	BetA	88..649	CDD:225186	180/597 (30%)
		NADB_Rossmann	185..375	CDD:304358	73/212 (34%)
		GMC_oxred_C	490..638	CDD:282984	45/148 (30%)
chdh	XP_002663301.2	PRK02106	30..585	CDD:235000	180/600 (30%)
		NADB_Rossmann	38..>69	CDD:304358	18/33 (55%)
		GMC_oxred_N	110..333	CDD:279121	81/241 (34%)
		GMC_oxred_C	424..561	CDD:282984	46/148 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.930