Protein Alignment CG12398 and betA

DIOPT Version :10

• Sequence 1: NP_572985.1
• Gene: CG12398 / 32422
• FlyBaseID: FBgn0030596
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_414845.1
• Gene: betA / 945716
• ECOCYCID: EG10109
• Length: 556
• Species: Escherichia coli
• Alignment Length: 604
• Identity: 212/604 - (35%)
• Similarity: 282/604 - (46%)
• Gaps: 113/604 - (18%)

  Fly    57 YDFIVIGGGSAGCVLAARLSENPEWSVLLLEAGGDE---------PLLIDLPQLYPVFQRSPWDW 112
            :|:|:||.||||.|||.||:|:|..|||||||||.:         |..:..|     .|...::|
E. coli     3 FDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFRTQMPAALAFP-----LQGKRYNW 62

  Fly   113 KYLTEPSDRYCLAMEDQRCFWPRAKVLGGCSSINAMMYIRGNRRDYDQWAALGNPG---WNYDNI 174
            .|.|||..    .|.::|....|.|.|||.|.||.|.|||||..|.|.||.  .||   |:|.:.
E. coli    63 AYETEPEP----FMNNRRMECGRGKGLGGSSLINGMCYIRGNALDLDNWAQ--EPGLENWSYLDC 121

  Fly   175 LHYFRKLE--DMRVPGFEHSPYHGHGGPISVERYRFP--SPLLDIFMRAAQQLGMVHPDGDFNGR 235
            |.|:||.|  ||     ..:.|||..||:||...: |  :||.:..:.|..|.|....| |.||.
E. coli   122 LPYYRKAETRDM-----GENDYHGGDGPVSVTTSK-PGVNPLFEAMIEAGVQAGYPRTD-DLNGY 179

  Fly   236 SQTGFAPPHGSLR-DGLRCSANKGYIRRSWQRPNLDIVLKAFVERIVIDPQSHRAIGVIFEYG-- 297
            .|.||.|...::. .|.|.|..:||:.::..||||.|...|..:.|:.|  ..||:||.:..|
E. coli   180 QQEGFGPMDRTVTPQGRRASTARGYLDQAKSRPNLTIRTHAMTDHIIFD--GKRAVGVEWLEGDS 242

  Fly   298 LLKHTVRAKREVILSAGSLASPQLLMVSGVGPRDQLEPQGIPVVQHLPGVGGNLQDHISTSGAIY 362
            .:.....|.:||:|.||::||||:|..||||..:.|....||:|..|||||.|||||:
E. coli   243 TIPTRATANKEVLLCAGAIASPQILQRSGVGNAELLAEFDIPLVHELPGVGENLQDHL------- 300

  Fly   363 TFDSGQNRHLSFIVPEMMNEQAVEDFVQGSDSFFYAMPVSEVMGFFSTRYQDPRLDW---PDV-- 422
                           ||..:...::            |||..          |.|.|   |.:
E. coli   301 ---------------EMYLQYECKE------------PVSLY----------PALQWWNQPKIGA 328

  Fly   423 QIFMGSYGYGAD-----GGMIGRRGAAITLDNYAEAFEPV---------LYQDSFVIAPLLMRPR 473
            :...|..|.||.     ||.| |........|....|.||         :.:..|......||..
E. coli   329 EWLFGGTGVGASNHFEAGGFI-RSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSP 392

  Fly   474 SRGYLQLRSADPKVHPLIHANYYDDPHDMAVMVEGLKLAHRLTQTPVMQSLNATMNIYEWRN-CP 537
            |||:::::|.||..||.|..||.....|.....:.:::...:...|.:..       |..|. .|
E. coli   393 SRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQ-------YRGREISP 450

  Fly   538 EVEYLSDAFWECLARFYSQTIYHPVGTCKMAPASDPAGVVDPRLRVRGMRGLRVIDASIMPTIPT 602
            .||..:|...:...|.:::|.:||.|||||  ..|...|||...||.|:.||||:||||||.|.|
E. coli   451 GVECQTDEQLDEFVRNHAETAFHPCGTCKM--GYDEMSVVDGEGRVHGLEGLRVVDASIMPQIIT 513

  Fly   603 GNTNAPTLMLAERGADIIK 621
            ||.||.|:|:.|:.||:|:
E. coli   514 GNLNATTIMIGEKIADMIR 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12398	NP_572985.1	BetA	54..626	CDD:441878	212/604 (35%)
betA	NP_414845.1	PRK02106	1..555	CDD:235000	212/604 (35%)