Protein Alignment CG12398 and ninaG

DIOPT Version :9

• Sequence 1: NP_572985.1
• Gene: CG12398 / 32422
• FlyBaseID: FBgn0030596
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_650070.1
• Gene: ninaG / 41369
• FlyBaseID: FBgn0037896
• Length: 597
• Species: Drosophila melanogaster
• Alignment Length: 654
• Identity: 172/654 - (26%)
• Similarity: 287/654 - (43%)
• Gaps: 122/654 - (18%)

  Fly    15 LTLGPSAMIILLLNKGILEQRPDIVDEQHRVRSIHIEDLRESYDFIVIGGGSAGCVLAARLSENP 79
            :.:|..::|::|....:....|:::....|    |.     ::|::::|||:.|..|.:.|::|.
  Fly    14 IVIGFLSIIVVLAGTLLKNSVPNVLAPVER----HF-----AFDYVIVGGGTGGSTLTSLLAKNS 69

  Fly    80 EWSVLLLEAGGDEPLLIDLPQLYPVFQRSPWDWKYLTEPSDRYCLAMEDQRCFWPRAKVLGGCSS 144
            ..||||:||||...||..:|.|....|:...||.:|:.|.......:.::|...||.|.|||.::
  Fly    70 NGSVLLIEAGGQFGLLSRIPLLTTFQQKGINDWSFLSVPQKHSSRGLIERRQCLPRGKGLGGSAN 134

  Fly   145 INAMMYIRGNRRDYDQWAALGN-PGWNYDNILHYFR----KLEDM-RVPGFEHSPYHGHGGPISV 203
            :|.|::..|:..|:|.|....| ..|::..:..:..    |..|| .:|
  Fly   135 LNYMLHFDGHGPDFDSWRDHHNLSDWSWAQMRSFMAAAKPKNPDMLEIP---------------- 183

  Fly   204 ERYRFPSPLLDIFMRAAQQLGMVHPDGDFNGRSQTGFAPPHGSLRDGLRCSANKGYIRRSWQRPN 268
            .||   |.|.:....|..|  ..:.|..|. ||..       ::|:|||.|..:.::.......|
  Fly   184 RRY---SKLTEALEEAQAQ--FAYKDWIFR-RSLY-------NIRNGLRHSVVQQFLNPVIHHSN 235

  Fly   269 LDIVLKAFVERIVIDPQ-----SHRAIGVIFEYGLLKH-TVRAKREVILSAGSLASPQLLMVSGV 327
            |.::..|.|:||.:.|.     :...:|:..|....|. ::..:||:||.||:..:|||||.||:
  Fly   236 LRLLPDALVKRIQLAPSPFLQATSILVGIKDEENREKEFSIEVRRELILCAGAYQTPQLLMASGI 300

  Fly   328 GPRDQLEPQGIPVVQHLPGVGGNLQDHIS----TSGAIYTFDSGQNRHLSFIVPEMMNEQAVEDF 388
            |....|:..|||....||.||.||.||.:    .|..:......||        .::|...:.::
  Fly   301 GDVSALKKLGIPAQHSLPLVGHNLHDHFNLPLFVSMGVTGPTLNQN--------TLLNPMTLINY 357

  Fly   389 VQGSDSFFYAMPVSEVMGFFSTRYQDPRLDWPDVQIFMG---SYG------YGA---DGGMIGRR 441
            :...         |..:|.|..               :|   |||      ||.   ..|.|. .
  Fly   358 LSSG---------SGPLGNFGV---------------LGNVVSYGGLGAPPYGITFFGAGAID-E 397

  Fly   442 GAAITLDNYA----EAFEPVLY---QDSFVIAPLLMRPRSRGYLQLRSADPKVHPLIHANYYDDP 499
            .|.:::.|:.    .|..|..|   |:.||:....::|:|||.:.|.:...:.:|||..||....
  Fly   398 SALMSISNFKGPAFRALFPRYYNSSQEGFVVISSCLQPKSRGSVGLLNRHMRRNPLIDPNYLSSE 462

  Fly   500 HDMAVMVEGLKLAHRLTQTPVMQSLNATMNIYEWRNCP-----EVEYL----SDAFWECLARFYS 555
            .|:|..:..::.|..|..:....:|:..::....:.|.     |.::.    ||.:.|||.|...
  Fly   463 EDVACTISAIRSAVELVNSTAFAALHPRIHWPRVQECSNFGPFERDFFDNRPSDQYLECLMRHVG 527

  Fly   556 QTIYHPVGTCKMAPASDPAGVVDPRLRVRGMRGLRVIDASIMPTIPTGNTNAPTLMLAERGAD-I 619
            ...:||.|||.:      ..|||.:||::|:..:||:|||::|...:||.|:..:.:|.|.|. |
  Fly   528 LGSHHPGGTCAL------GSVVDSQLRLKGVSNVRVVDASVLPRPISGNPNSVVVAIALRAASWI 586

  Fly   620 IKED 623
            :|.:
  Fly   587 LKSE 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12398	NP_572985.1	PRK02106	55..632	CDD:235000	166/614 (27%)
		NADB_Rossmann	58..>93	CDD:304358	16/34 (47%)
		NADB_Rossmann	129..354	CDD:304358	68/236 (29%)
		GMC_oxred_C	472..615	CDD:282984	44/151 (29%)
ninaG	NP_650070.1	BetA	72..588	CDD:225186	157/583 (27%)
		NADB_Rossmann	119..327	CDD:304358	68/236 (29%)
		GMC_oxred_C	435..582	CDD:282984	44/152 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446448
Domainoid	1	1.000	69	1.000	Domainoid score	I3423
eggNOG	1	0.900	-	-		E1_COG2303
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm47571
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11552
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
	8	7.940