Protein Alignment CG12398 and CG9522

DIOPT Version :9

• Sequence 1: NP_572985.1
• Gene: CG12398 / 32422
• FlyBaseID: FBgn0030596
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_644677.1
• Gene: CG9522 / 32413
• FlyBaseID: FBgn0030587
• Length: 616
• Species: Drosophila melanogaster
• Alignment Length: 637
• Identity: 245/637 - (38%)
• Similarity: 353/637 - (55%)
• Gaps: 44/637 - (6%)

  Fly    10 MWRFLLTLGPSAMIILLLNKGILEQRPDIVDEQHRVRSIHIEDL-------RESYDFIVIGGGSA 67
            |.:.|||    .::.|||...|..||...:||..|:...::.::       :.:||||::|||:|
  Fly     1 MEKLLLT----QLLFLLLIPLIHSQRSSQLDELRRLGLGNVVNVPFFSDVPQRNYDFIIVGGGAA 61

  Fly    68 GCVLAARLSENPEWSVLLLEAGGDEPLLIDLPQLYPVFQRSPWDWKYLTEPSDRYCLAMEDQRCF 132
            ||.|||||||||.|||.|:||||.|.::..:|.|....|.:..:|.|.:.|....|..|.|.:|.
  Fly    62 GCTLAARLSENPNWSVFLIEAGGVENIVHQVPLLAAHLQSTASNWGYNSTPQRHACRGMPDNKCA 126

  Fly   133 WPRAKVLGGCSSINAMMYIRGNRRDYDQWAALGNPGWNYDNILHYFRKLEDMRVPGFEHSPYHGH 197
            .||.|||||.||||.|:|.||||||:|.|||.|||||:||.:|.||.:.|..::.|.||||||.|
  Fly   127 LPRGKVLGGTSSINYMIYNRGNRRDFDAWAAAGNPGWSYDEVLPYFLRSEHAQLQGLEHSPYHNH 191

  Fly   198 GGPISVERYRFPSPLLDIFMRAAQQLGMVHPDGDFNGRSQTGFAPPHGSLRDGLRCSANKGYIR- 261
            .||:|||..|..:.|...::||||:.|  ||..|:||.||.|.:....:...|.|.||.:.||.
  Fly   192 SGPLSVEDVRHRTRLAHAYIRAAQEAG--HPRTDYNGESQLGVSYVQATTLKGRRHSAFRAYIEP 254

  Fly   262 -RSWQRPNLDIVLKAFVERIVIDPQSHRAIGVIFEYGLLKHTVRAKREVILSAGSLASPQLLMVS 325
             || :|.||.|:..|.|.|::||..:..|.||...:......|:|::|:|||||:..||||||:|
  Fly   255 IRS-RRHNLHILTLARVTRVLIDAATKSAYGVELTHQGRSFKVKARKEIILSAGAFNSPQLLMLS 318

  Fly   326 GVGPRDQLEPQGIPVVQHLPGVGGNLQDHISTSGAIY-TFDSGQNRHLSFIVPEMMNEQAVEDFV 389
            |:||.|.|:..|||:::.|| ||..:.||:...|..: |..:||.     :....:.....::|:
  Fly   319 GIGPEDNLKAIGIPLIKALP-VGKRMFDHMCHFGPTFVTNTTGQT-----LFAAQLGAPVAKEFL 377

  Fly   390 QG-SDSFFYAMPVSEVMGFFSTRYQDPRLDWPDVQIFMGSYGYGADGGMIGRRGAAITLDNYAEA 453
            .| :|:|..::...|.:.|............|||::...:....:|.|....:||         .
  Fly   378 LGRADTFLSSIGGVETLTFIKVPSGKSPATQPDVELIQVAGSLASDDGTALAKGA---------N 433

  Fly   454 FEPVLY-----------QDSFVIAPLLMRPRSRGYLQLRSADPKVHPLIHANYYDDPHDMAVMVE 507
            |:|.:|           ||.|....:..:|.|.|.|.|.:.:|...|.|...|:..|.|:..::|
  Fly   434 FKPEIYEKMYKNLTLRQQDHFSFLIMHFKPASVGRLWLHNRNPLEWPRIDPKYFSAPSDVENLLE 498

  Fly   508 GLKLAHRLTQTPVMQSLNATMNIYEWRNCPEVEYLSDAFWECLARFYSQTIYHPVGTCKMAPASD 572
            |:|.|.|:::.|.||::...:.......|...|:.||.:|.|..|..|.|::|.|.||:|...||
  Fly   499 GIKEALRISKMPAMQAIGTRLLDKPVPGCENYEFASDDYWRCSIRTLSYTLHHQVATCRMGAESD 563

  Fly   573 PAGVVDPRLRVRGMRGLRVIDASIMPTIPTGNTNAPTLMLAERGADIIKEDW 624
            |..||:.:|:|.|:|.|||:|.||:|..||.:|||...|:.|:.||:|:.:|
  Fly   564 PTTVVNHQLKVHGVRKLRVVDTSIIPFPPTAHTNAAAFMIGEKAADMIRSEW 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12398	NP_572985.1	PRK02106	55..632	CDD:235000	232/585 (40%)
		NADB_Rossmann	58..>93	CDD:304358	26/34 (76%)
		NADB_Rossmann	129..354	CDD:304358	110/226 (49%)
		GMC_oxred_C	472..615	CDD:282984	55/142 (39%)
CG9522	NP_644677.1	PRK02106	48..612	CDD:235000	230/581 (40%)
		NADB_Rossmann	52..>83	CDD:304358	23/30 (77%)
		NADB_Rossmann	127..348	CDD:304358	111/224 (50%)
		GMC_oxred_C	463..607	CDD:282984	56/143 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446479
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm24368
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	1	1.100	-	-	P	PTHR11552
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
	10	9.890