Protein Alignment CG12398 and Chdh

DIOPT Version :9

• Sequence 1: NP_572985.1
• Gene: CG12398 / 32422
• FlyBaseID: FBgn0030596
• Length: 633
• Species: Drosophila melanogaster
• Sequence 2: NP_942026.1
• Gene: Chdh / 290551
• RGDID: 735166
• Length: 599
• Species: Rattus norvegicus
• Alignment Length: 608
• Identity: 213/608 - (35%)
• Similarity: 294/608 - (48%)
• Gaps: 113/608 - (18%)

  Fly    54 RESYDFIVIGGGSAGCVLAARLSENPEWSVLLLEAGGDEPLL--------IDLP-QLYPVFQRSP 109
            ::.|.|||:|.||||||||.||:|:|...|||||||..:.|:        |.:| .|........
  Rat    43 KDEYTFIVVGAGSAGCVLANRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVANLCDDK 107

  Fly   110 WDWKYLTEPSDRYCLAMEDQRCFWPRAKVLGGCSSINAMMYIRGNRRDYDQWAALGNPGWNYDNI 174
            ::|.|.||...    .::.:..:|||.:|.||.||:|||:||||:..||::|...|..||:|.:.
  Rat   108 YNWYYHTEAQP----GLDGRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHRQGAEGWDYAHC 168

  Fly   175 LHYFRKLEDMRVPGFEHSPYHGHGGPISVERYRFPSPLLDIFMRAAQQLGMVHPDGDFNGRSQTG 239
            |.||||.:...:..   :.|.|..||:.|.|.:...||...|::||:|.|....: |.||..|.|
  Rat   169 LPYFRKAQKHELGA---NMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTE-DMNGFQQEG 229

  Fly   240 FAPPHGSLRDGLRCSANKGYIRRSWQRPNLDIVLKAFVERIVIDPQSHRAIGVIFEYGLLKHTVR 304
            |.....::..|.|.|....|:|.:..||||...::..|.|::.  :..||:||.:......|...
  Rat   230 FGWMDMTIHQGKRWSTASAYLRPALSRPNLRAEVQTLVSRVLF--EGTRAVGVEYIKDGQSHKAY 292

  Fly   305 AKREVILSAGSLASPQLLMVSGVGPRDQLEPQGIPVVQHLPGVGGNLQDHISTSGAIY------- 362
            ..||||||.|::.||||||:||||..|.|:..|||||.||||||.|||||:.    ||
  Rat   293 VSREVILSGGAINSPQLLMLSGVGNADDLKKLGIPVVCHLPGVGQNLQDHLE----IYIQHACTQ 353

  Fly   363 --TFDS---------------------GQNRHLSFIVPEMMNEQAVEDFVQGSDSFFYAMPVSEV 404
              |..|                     |...||                              |.
  Rat   354 PITLHSAQKPLRKVCIGLEWLWRFTGDGATAHL------------------------------ET 388

  Fly   405 MGFFSTRYQDPRLDWPDVQI-FMGSYGYGADGGMIGRRGAAITLDNYAEAFEPVLYQDSFVIAPL 468
            .||..:|   |.:..||:|. |:.|.                .:|:..:..:    |:::.:...
  Rat   389 GGFIRSR---PGVPHPDIQFHFLPSQ----------------VIDHGRKPTQ----QEAYQVHVG 430

  Fly   469 LMRPRSRGYLQLRSADPKVHPLIHANYYDDPHDMAVMVEGLKLAHRLTQTPVMQSLNATMNIYEW 533
            .||..|.|:|:|||.:|:.||:|:.||.....|    ||..:...:||:....|...|.....|.
  Rat   431 TMRATSVGWLKLRSTNPQDHPMINPNYLSTETD----VEDFRQCVKLTREIFAQEAFAPFRGKEL 491

  Fly   534 RNCPEVEYLSDAFWECLARFYSQTIYHPVGTCKMAPASDPAGVVDPRLRVRGMRGLRVIDASIMP 598
            :  |.....||...:...|..:.:.|||..||||...|||..|||.:.||.|:..||||||||||
  Rat   492 Q--PGSHVQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDQQTRVIGVENLRVIDASIMP 554

  Fly   599 TIPTGNTNAPTLMLAERGADIIK 621
            ::.:||.||||:|:||:.||:||
  Rat   555 SVVSGNLNAPTIMIAEKAADVIK 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12398	NP_572985.1	PRK02106	55..632	CDD:235000	213/607 (35%)
		NADB_Rossmann	58..>93	CDD:304358	23/34 (68%)
		NADB_Rossmann	129..354	CDD:304358	95/224 (42%)
		GMC_oxred_C	472..615	CDD:282984	58/142 (41%)
Chdh	NP_942026.1	PRK02106	45..591	CDD:235000	213/606 (35%)
		NADB_Rossmann	49..>151	CDD:304358	45/105 (43%)
		GMC_oxred_N	121..344	CDD:279121	97/228 (43%)
		GMC_oxred_C	435..572	CDD:282984	59/142 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	244	1.000	Domainoid score	I2129
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	342	1.000	Inparanoid score	I2269
OMA	1	1.010	-	-		QHG52181
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm44531
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.870