DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fiz and AT5G51930

DIOPT Version :9

Sequence 1:	NP_001285254.1	Gene:	fiz / 32420	FlyBaseID:	FBgn0030594	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_200006.1	Gene:	AT5G51930 / 835268	AraportID:	AT5G51930	Length:	582	Species:	Arabidopsis thaliana

Alignment Length:	598	Identity:	164/598 - (27%)
Similarity:	260/598 - (43%)	Gaps:	141/598 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 YDFVVIGAGSAGSVVASRLSENPDWRVLVLEAGGDP---PVESELPALFFG------LQHTNFTW 124
            :|:::||.|:||..:|:.||:|..  |||||.||.|   |..:::     |      |.:|..:|
plant    73 FDYIIIGGGTAGCALAATLSQNAS--VLVLERGGSPYENPTATDM-----GNSVNTLLNNTPNSW 130

  Fly   125 N--YFTEPSDEACQAMKDGRCYWPRGKMLGGSGGVNAMLYVR-GNRRDFDGWAAMGSTGWSYDQV 186
            :  :.:|          || .|..|.::|||...:|...|.| ||  |:     :....|..::|
plant   131 SQLFISE----------DG-VYNTRPRVLGGGSVINGGFYSRAGN--DY-----VEEAEWEMEEV 177

  Fly   187 MPFFEKSVTPQGNATHPKGYVTLK-PFERKDNDIHQMIIDGGRELGQPYVERFQEGSDTG--YSH 248
            ...:|              :|..| .||.:..:..:...||..|.|        |..|.|  |.|
plant   178 EAAYE--------------WVEKKLVFEPQVIEWQKAFKDGLLEAG--------ESPDNGFTYDH 220

  Fly   249 VPGTV-------RQGQRMSTGKGYLGAVSKSRPNLHVV-KNALVTKLDLDGETVKEVKFERA-GV 304
            :.||.       |.|.|.:..    ..:..:.||..|| .:|.|.|:....|.. ||.||.| ||
plant   221 IYGTKIGGTIFDRAGHRHTAA----NLLEYANPNRIVVYLHASVHKVLFTTEAY-EVLFEDANGV 280

  Fly   305 THRV----KVTKDVVISAGAIDSPALLLRSGIGPSKHLKELGI-PVKLDLPGVGRNLQDHVL--- 361
            .|:.    |.|.:|::||||:.||.||:.||:||:.||:..|: |:.||.|.||:.:.|:.:
plant   281 FHKANLANKATNEVILSAGALGSPQLLMLSGVGPAVHLEAHGVNPLVLDQPMVGQGMADNPMNFV 345

  Fly   362 -----VPVFLRLDEGQGEPMTDQAALDSIYQYLIYRAGPLAAHSTASLVGFINTNASSDGAYPDT 421
                 .||.|.|.:..|           |.::..|..| |:..|    :.|..|....||..
plant   346 AIPSPQPVELSLIQAVG-----------ITKFDSYIEG-LSGLS----LSFDITRRFFDGVL--- 391

  Fly   422 ENHHMFFQRAHHASLELFTKGLSIQDQYTEVLQEYLKDSHLLCVFVLLSHPAARGELRLKSTDPK 486
               ::..:.:|..|.::.|:.:::..:..:|..|...:..|  :|..:..||::|.::|::|:|:
plant   392 ---NLLNETSHTTSRKILTQSIAVLLKSFDVKLEVRMNGGL--IFQKVDGPASKGHMKLRNTNPR 451

  Fly   487 VPPILTSNYLTESEDVATLMRGIRYIESLEQTKAFQDH----------LAEIARIPIKECDQIEN 541
            ..|.:|.||..|.||:...::|:..|..:..:|||..:          |..:..:||       |
plant   452 DNPSVTFNYYQEPEDLNKCVKGLNTIIRMINSKAFSKYKYPGVTARELLNLMLALPI-------N 509

  Fly   542 YRSEEYWRCY-AKYF---TVT-CYHQSGTVKMGPDYDNEACVSQRLKVHGLENLRVADASIMPAV 601
            .|.......: .|.|   ||| .:|..|..::|      ..|.:..||.|::.|||.|.|.....
plant   510 LRPRHVTSAFNLKQFCIDTVTSVWHYHGGCQVG------KVVDKNYKVLGIDGLRVIDGSTFLKS 568

  Fly   602 VSANTNAATVMIG 614
            ...|..|..:|:|
plant   569 PGTNPQATVMMLG 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fiz	NP_001285254.1	PRK02106	66..621	CDD:235000	164/598 (27%)
		NADB_Rossmann	70..>105	CDD:304358	18/37 (49%)
		NADB_Rossmann	142..359	CDD:304358	72/234 (31%)
		GMC_oxred_C	472..617	CDD:282984	44/158 (28%)
AT5G51930	NP_200006.1	BetA	70..582	CDD:225186	164/598 (27%)
		NADB_Rossmann	73..317	CDD:304358	89/295 (30%)
		GMC_oxred_C	437..581	CDD:282984	43/156 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D798314at2759
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		mtm950
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730