DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fiz and AT3G56060

DIOPT Version :9

Sequence 1:	NP_001285254.1	Gene:	fiz / 32420	FlyBaseID:	FBgn0030594	Length:	646	Species:	Drosophila melanogaster
Sequence 2:	NP_567032.1	Gene:	AT3G56060 / 824772	AraportID:	AT3G56060	Length:	577	Species:	Arabidopsis thaliana

Alignment Length:	612	Identity:	155/612 - (25%)
Similarity:	253/612 - (41%)	Gaps:	144/612 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 YDFVVIGAGSAGSVVASRLSENPDWRVLVLEAGGDP---PVESELPALFFGLQHTNFTWNYFTEP 130
            :|:::||.|:||..:|:.||:|.  .|||||.||.|   |..:::..  |.....|.|.|.:::
plant    46 FDYIIIGGGTAGCALAATLSQNA--TVLVLERGGSPYDDPAATDIGN--FANTLLNITPNSWSQ- 105

  Fly   131 SDEACQAMKDGRCYWPRGKMLGGSGGVNAMLYVRGNRRDFDGWAAMGSTGWSYDQV---MPFFEK 192
                ....:|| .:..|.::|||...:||..|.|. ..||     :...||..|:|   ..:.||
plant   106 ----LFISEDG-VFNSRARVLGGGTVINAGFYSRA-EEDF-----VAEAGWERDEVEAAYEWVEK 159

  Fly   193 SVTPQGNATHPKGYVTLKPFERKDNDIHQMIIDGGRELG-QPYVERFQEGSDTGYSHVPGTV--- 253
            .|.                ||...|.......||..|.| .||       :...|.|:.||.
plant   160 KVV----------------FEPPVNKWQSAFRDGLLEAGVTPY-------NGFTYEHIVGTKFGG 201

  Fly   254 ----RQGQRMSTGKGYLGAVSKSRPNLHVV-KNALVTKLDLDGETVKEVKFERA---------GV 304
                |.|.|.:..    ..:..:.||:.|| .:|.|.|:..   |:|..:..:|         ||
plant   202 TIFDRDGHRHTAA----NLLEYANPNMIVVYLHASVHKILF---TIKGNQRPKAYGVIFLDANGV 259

  Fly   305 THRVKV-TKD-----VVISAGAIDSPALLLRSGIGPSKHLKELGI-PVKLDLPGVGRNLQDHVLV 362
            :::.:: |:|     |::|||||.||.||:.||:||:.||....: ||.:|.|.||:.:.|:.:.
plant   260 SYKAELATQDSTMSEVILSAGAIASPQLLMLSGVGPAAHLAAYRVNPVIVDQPMVGQGMGDNPMN 324

  Fly   363 PVFLRLDEGQGEPMTDQAALDSIYQYLIYRAGPLAAHSTASLVGFINTNASSDGAYP-------D 420
            |||:        |..:...:..:....|.:.|......:|..:....|.:..||...       .
plant   325 PVFI--------PSPEPVEVSLVQAVGITKFGSYIEGGSALSLSISLTRSFFDGVLNLLKKTKLP 381

  Fly   421 TENHHMFFQRAHHASLELFTKGLSIQDQYTEVLQEYLKDSHLLCVFVLLSHPAARGELRLKSTDP 485
            |::...||:     ||:|   .|::..:...::|:             ::.|.:||.|.|::|:|
plant   382 TQSISKFFK-----SLDL---TLNVTTKAGVIIQK-------------VNGPLSRGHLELRNTNP 425

  Fly   486 KVPPILTSNYLTESEDVATLMRGIRYIESLEQTKAFQDH----------LAEIARIP--IKECDQ 538
            ...|.:|.||..:.||:...:.|:..|..:..:|.:..:          |..|..:|  ::....
plant   426 DDNPSVTFNYFKDPEDLNKCVEGLSTIIKVIDSKGYSKYKYPLASARGLLNLILALPTNLRPRHI 490

  Fly   539 IENYRSEEYWRCYAKYFTVTCYHQSGTVKMGPDYDNEACVSQRLKVHGLENLRVADASIMPAVVS 603
            ...:..|:|  |.....|:  ||..|..::|...||      ..||.|::.||:.|.|.......
plant   491 TSTFDLEQY--CIDTVMTI--YHYHGGCQVGKVVDN------NYKVLGVDALRIIDGSTFLKSPG 545

  Fly   604 ANTNAATVMIGERAAHFIQEDYQGEAV 630
            .|..|..:|:|.         |.|:.:
plant   546 TNPQATIMMLGR---------YMGQKI 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fiz	NP_001285254.1	PRK02106	66..621	CDD:235000	153/601 (25%)
		NADB_Rossmann	70..>105	CDD:304358	18/37 (49%)
		NADB_Rossmann	142..359	CDD:304358	69/244 (28%)
		GMC_oxred_C	472..617	CDD:282984	40/156 (26%)
AT3G56060	NP_567032.1	PLN02785	5..568	CDD:215420	155/612 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D798314at2759
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		mtm950
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730