Protein Alignment fiz and CHDH

DIOPT Version :10

• Sequence 1: NP_572983.1
• Gene: fiz / 32420
• FlyBaseID: FBgn0030594
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_060867.2
• Gene: CHDH / 55349
• HGNCID: 24288
• Length: 594
• Species: Homo sapiens
• Alignment Length: 604
• Identity: 195/604 - (32%)
• Similarity: 293/604 - (48%)
• Gaps: 76/604 - (12%)

  Fly    42 QTLLSSQCLVSPASQWPVDYVGDLSQPYDFVVIGAGSAGSVVASRLSENPDWRVLVLEAG----- 101
            |..|.::.|.|..|        :....|.:||:||||||.|:|.||:|:|..|||:||||
Human    22 QQSLGARALASAGS--------ESRDEYSYVVVGAGSAGCVLAGRLTEDPAERVLLLEAGPKDVL 78

  Fly   102 -GDPPVESEL---PALFFGLQHTNFTWNYFTEPSDEACQAMKDGR-CYWPRGKMLGGSGGVNAML 161
             |...:..::   .||...|....:.|.|.||     .|...||| .|||||::.|||..:|||:
Human    79 AGSKRLSWKIHMPAALVANLCDDRYNWCYHTE-----VQRGLDGRVLYWPRGRVWGGSSSLNAMV 138

  Fly   162 YVRGNRRDFDGWAAMGSTGWSYDQVMPFFEKSVTPQGNATHPKGY-VTLKPFERKDN-DIHQMII 224
            ||||:..|::.|...|:.||.|...:|:|.|:...:..|:..:|. ..|:....|.| .:|...:
Human   139 YVRGHAEDYERWQRQGARGWDYAHCLPYFRKAQGHELGASRYRGADGPLRVSRGKTNHPLHCAFL 203

  Fly   225 DGGRELGQPYVERFQEGSDTGYSHVPGTVRQGQRMSTGKGYLGAVSKSRPNLHVVKNALVTKLDL 289
            :..::.|.|..|........|:..:..|:.:|:|.|....||.. :.||.||......||:::..
Human   204 EATQQAGYPLTEDMNGFQQEGFGWMDMTIHEGKRWSAACAYLHP-ALSRTNLKAEAETLVSRVLF 267

  Fly   290 DGETVKEVKFERAGVTHRVKVTKDVVISAGAIDSPALLLRSGIGPSKHLKELGIPVKLDLPGVGR 354
            :|.....|::.:.|.:||...:|:|::|.|||:||.||:.||||.:..||:|||||...|||||:
Human   268 EGTRAVGVEYVKNGQSHRAYASKEVILSGGAINSPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQ 332

  Fly   355 NLQDHVLVPVFLRLDEGQGEPMTDQAALDSIYQYLI-------YRAGPLAAHSTASLVGFINTNA 412
            |||||:.:    .:.:....|:|..:|...:.:..|       :......||....  |||.
Human   333 NLQDHLEI----YIQQACTRPITLHSAQKPLRKVCIGLEWLWKFTGEGATAHLETG--GFIR--- 388

  Fly   413 SSDGA-YPDTENHHMFFQRAHHASLELFTKGLSIQDQYTEVLQEYLKDSHLLCVFVLLSHPAARG 476
            |..|. :||.:.|.:..|...|..:.      :.|:.|.              |.|......:.|
Human   389 SQPGVPHPDIQFHFLPSQVIDHGRVP------TQQEAYQ--------------VHVGPMRGTSVG 433

  Fly   477 ELRLKSTDPKVPPILTSNYL---TESEDVATLMRGIRYIESLEQTKAFQDHLAEIARIPIKECDQ 538
            .|:|:|.:|:..|::..|||   |:.||....::..|.|.:.|....|:.          ||...
Human   434 WLKLRSANPQDHPVIQPNYLSTETDIEDFRLCVKLTREIFAQEALAPFRG----------KELQP 488

  Fly   539 IENYRSEEYWRCYAKYFTVTCYHQSGTVKMGPDYDNEACVSQRLKVHGLENLRVADASIMPAVVS 603
            ..:.:|::....:.:....:.||.|.|.|||...|..|.|..:.:|.|:|||||.||||||::||
Human   489 GSHIQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDPQTRVLGVENLRVVDASIMPSMVS 553

  Fly   604 ANTNAATVMIGERAAHFIQ 622
            .|.||.|:||.|:||..|:
Human   554 GNLNAPTIMIAEKAADIIK 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fiz	NP_572983.1	BetA	66..627	CDD:441878	190/580 (33%)
CHDH	NP_060867.2	PRK02106	40..594	CDD:235000	190/578 (33%)