Protein Alignment fiz and CHDH

DIOPT Version :9

• Sequence 1: NP_001285254.1
• Gene: fiz / 32420
• FlyBaseID: FBgn0030594
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_060867.2
• Gene: CHDH / 55349
• HGNCID: 24288
• Length: 594
• Species: Homo sapiens
• Alignment Length: 604
• Identity: 195/604 - (32%)
• Similarity: 293/604 - (48%)
• Gaps: 76/604 - (12%)

  Fly    42 QTLLSSQCLVSPASQWPVDYVGDLSQPYDFVVIGAGSAGSVVASRLSENPDWRVLVLEAG----- 101
            |..|.::.|.|..|        :....|.:||:||||||.|:|.||:|:|..|||:||||
Human    22 QQSLGARALASAGS--------ESRDEYSYVVVGAGSAGCVLAGRLTEDPAERVLLLEAGPKDVL 78

  Fly   102 -GDPPVESEL---PALFFGLQHTNFTWNYFTEPSDEACQAMKDGR-CYWPRGKMLGGSGGVNAML 161
             |...:..::   .||...|....:.|.|.||     .|...||| .|||||::.|||..:|||:
Human    79 AGSKRLSWKIHMPAALVANLCDDRYNWCYHTE-----VQRGLDGRVLYWPRGRVWGGSSSLNAMV 138

  Fly   162 YVRGNRRDFDGWAAMGSTGWSYDQVMPFFEKSVTPQGNATHPKGY-VTLKPFERKDN-DIHQMII 224
            ||||:..|::.|...|:.||.|...:|:|.|:...:..|:..:|. ..|:....|.| .:|...:
Human   139 YVRGHAEDYERWQRQGARGWDYAHCLPYFRKAQGHELGASRYRGADGPLRVSRGKTNHPLHCAFL 203

  Fly   225 DGGRELGQPYVERFQEGSDTGYSHVPGTVRQGQRMSTGKGYLGAVSKSRPNLHVVKNALVTKLDL 289
            :..::.|.|..|........|:..:..|:.:|:|.|....||.. :.||.||......||:::..
Human   204 EATQQAGYPLTEDMNGFQQEGFGWMDMTIHEGKRWSAACAYLHP-ALSRTNLKAEAETLVSRVLF 267

  Fly   290 DGETVKEVKFERAGVTHRVKVTKDVVISAGAIDSPALLLRSGIGPSKHLKELGIPVKLDLPGVGR 354
            :|.....|::.:.|.:||...:|:|::|.|||:||.||:.||||.:..||:|||||...|||||:
Human   268 EGTRAVGVEYVKNGQSHRAYASKEVILSGGAINSPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQ 332

  Fly   355 NLQDHVLVPVFLRLDEGQGEPMTDQAALDSIYQYLI-------YRAGPLAAHSTASLVGFINTNA 412
            |||||:.:    .:.:....|:|..:|...:.:..|       :......||....  |||.
Human   333 NLQDHLEI----YIQQACTRPITLHSAQKPLRKVCIGLEWLWKFTGEGATAHLETG--GFIR--- 388

  Fly   413 SSDGA-YPDTENHHMFFQRAHHASLELFTKGLSIQDQYTEVLQEYLKDSHLLCVFVLLSHPAARG 476
            |..|. :||.:.|.:..|...|..:.      :.|:.|.              |.|......:.|
Human   389 SQPGVPHPDIQFHFLPSQVIDHGRVP------TQQEAYQ--------------VHVGPMRGTSVG 433

  Fly   477 ELRLKSTDPKVPPILTSNYL---TESEDVATLMRGIRYIESLEQTKAFQDHLAEIARIPIKECDQ 538
            .|:|:|.:|:..|::..|||   |:.||....::..|.|.:.|....|:.          ||...
Human   434 WLKLRSANPQDHPVIQPNYLSTETDIEDFRLCVKLTREIFAQEALAPFRG----------KELQP 488

  Fly   539 IENYRSEEYWRCYAKYFTVTCYHQSGTVKMGPDYDNEACVSQRLKVHGLENLRVADASIMPAVVS 603
            ..:.:|::....:.:....:.||.|.|.|||...|..|.|..:.:|.|:|||||.||||||::||
Human   489 GSHIQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDPQTRVLGVENLRVVDASIMPSMVS 553

  Fly   604 ANTNAATVMIGERAAHFIQ 622
            .|.||.|:||.|:||..|:
Human   554 GNLNAPTIMIAEKAADIIK 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fiz	NP_001285254.1	PRK02106	66..621	CDD:235000	189/577 (33%)
		NADB_Rossmann	70..>105	CDD:304358	22/40 (55%)
		NADB_Rossmann	142..359	CDD:304358	81/219 (37%)
		GMC_oxred_C	472..617	CDD:282984	51/147 (35%)
CHDH	NP_060867.2	PRK02106	40..594	CDD:235000	190/578 (33%)
		NADB_Rossmann	44..>149	CDD:304358	49/109 (45%)
		NADB_Rossmann	116..339	CDD:304358	85/223 (38%)
		GMC_oxred_C	430..567	CDD:282984	51/146 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	106	0.954	Domainoid score	I6564
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm40396
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.690