Protein Alignment fiz and CG12539

DIOPT Version :9

• Sequence 1: NP_001285254.1
• Gene: fiz / 32420
• FlyBaseID: FBgn0030594
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_572976.1
• Gene: CG12539 / 32412
• FlyBaseID: FBgn0030586
• Length: 626
• Species: Drosophila melanogaster
• Alignment Length: 597
• Identity: 202/597 - (33%)
• Similarity: 304/597 - (50%)
• Gaps: 60/597 - (10%)

  Fly    64 DLSQPYDFVVIGAGSAGSVVASRLSENPDWRVLVLEAGGDPPVESELPALFFGLQHTNFTWNYFT 128
            |||. |||:|||||:||..:|:||||||...|.::||||...:....|.:...||.|:..|.|.:
  Fly    54 DLSN-YDFIVIGAGAAGCTLAARLSENPQVSVALIEAGGVENIAHLTPVVAGYLQQTSSNWGYKS 117

  Fly   129 EPSDEACQAMKDGRCYWPRGKMLGGSGGVNAMLYVRGNRRDFDGWAAMGSTGWSYDQVMPFFEKS 193
            .|...:|..|.:..|..||||:|||:..:|.|:|.||||||||.|||.|:.|||||:|:|:|.:|
  Fly   118 VPQKLSCHGMNNNECALPRGKILGGTSSINYMIYNRGNRRDFDAWAAAGNPGWSYDEVLPYFLRS 182

  Fly   194 ---------VTPQGNATHPKG--YVTLKPFERKDNDIHQMI---IDGGRELGQPYVERFQEGSDT 244
                     .:|..|.:.|..  ||..:         .||:   ::...|.|.|..: :...|..
  Fly   183 EHAQLQGLEQSPYHNHSGPLSVEYVRFR---------SQMVDAFVEASVESGLPRTD-YNGESQL 237

  Fly   245 GYSHVPGTVRQGQRMSTGKGYLGAVSKSRPNLHVVKNALVTKLDLDGETVKE---VKFERAGVTH 306
            |.|:|......|:|.|....|:..|...|.||.:...:.||::.:| |..|.   |:|......:
  Fly   238 GVSYVQANTLNGRRHSAYSAYIKPVRDLRSNLQIFTFSQVTRILID-EATKSAYGVEFHYKNKAY 301

  Fly   307 RVKVTKDVVISAGAIDSPALLLRSGIGPSKHLKELGIPVKLDLPGVGRNLQDHV--LVPVFLRLD 369
            ..|..|:|::|||:.:||.||:.|||||..:|:.:|||:...|| ||:.:.||:  ..|.|:...
  Fly   302 TFKARKEVILSAGSFNSPQLLMLSGIGPEDNLRGIGIPLIKALP-VGKRMFDHMCHFGPTFVTNT 365

  Fly   370 EGQGEPMTDQAALDSIYQYLIYRAGPLAAHSTA----SLVGFINTNASS-DGAYPDTENHHMFFQ 429
            .|| ...|.:.....:..:|:  ||..|...::    ..:.|:.|..|: ...:||.|   :...
  Fly   366 TGQ-TTFTSRVTPAELISFLL--AGNPATRMSSIGGVEALAFLKTQRSNLPNDWPDIE---LIMV 424

  Fly   430 RAHHAS-----LELFTKGLSIQDQ-----YTEVLQEYLKDSHLLCVFVLLSHPAARGELRLKSTD 484
            ....||     |:|   |.:.:|:     |.|:.|  .:..| ..:.::..||.:.|.|.||..:
  Fly   425 TGSLASDEGTGLKL---GANFKDEIYDRMYRELAQ--AQQDH-FTLLIMQFHPKSVGRLWLKDRN 483

  Fly   485 PKVPPILTSNYLTESEDVATLMRGIRYIESLEQTKAFQDHLAEIARIPIKECDQIENYRSEEYWR 549
            |...|.:...|....|||..|:.||:....:.:..|.|...|.:.:..:..|:. ..:.|::|||
  Fly   484 PLGWPKIDPKYFVAEEDVEYLLDGIKASLRIIEMPAMQRIGARLLKRTVPGCEG-HQFASDDYWR 547

  Fly   550 CYAKYFTVTCYHQSGTVKMGPDYDNEACVSQRLKVHGLENLRVADASIMPAVVSANTNAATVMIG 614
            |..:..:.|.:||..|.:||.:.|....|:.:|||||:..|||.|.||:|...:|:||||..|||
  Fly   548 CSIRTLSYTLHHQVATCRMGAESDPTTVVNHQLKVHGVRKLRVVDTSIIPFPPTAHTNAAAFMIG 612

  Fly   615 ERAAHFIQEDYQ 626
            |:||..|:.|::
  Fly   613 EKAADMIRTDWE 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fiz	NP_001285254.1	PRK02106	66..621	CDD:235000	198/588 (34%)
		NADB_Rossmann	70..>105	CDD:304358	21/34 (62%)
		NADB_Rossmann	142..359	CDD:304358	84/233 (36%)
		GMC_oxred_C	472..617	CDD:282984	52/144 (36%)
CG12539	NP_572976.1	PRK02106	58..620	CDD:235000	197/586 (34%)
		NADB_Rossmann	59..>90	CDD:304358	18/30 (60%)
		NADB_Rossmann	128..355	CDD:304358	86/238 (36%)
		GMC_oxred_C	471..615	CDD:282984	52/144 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446474
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm24368
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	1	1.100	-	-	P	PTHR11552
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
	11	10.800