Protein Alignment fiz and chdh-1

DIOPT Version :9

• Sequence 1: NP_001285254.1
• Gene: fiz / 32420
• FlyBaseID: FBgn0030594
• Length: 646
• Species: Drosophila melanogaster
• Sequence 2: NP_495846.1
• Gene: chdh-1 / 174390
• WormBaseID: WBGene00007917
• Length: 599
• Species: Caenorhabditis elegans
• Alignment Length: 601
• Identity: 184/601 - (30%)
• Similarity: 290/601 - (48%)
• Gaps: 101/601 - (16%)

  Fly    72 VVIGAGSAGSVVASRLSENPDWRVLVLEAGGDPPVESE------LP-ALFFGLQHTNFTWNYFTE 129
            :::||||||.|:|:||:|:|..|||::|||   ||:.:      :| ||.:.|....:.|:|.|
 Worm    41 IIVGAGSAGCVLANRLTEDPSNRVLLIEAG---PVDHKWDWRIHMPAALMYNLCSDTYNWHYHT- 101

  Fly   130 PSDEACQAMKDGRCYWPRGKMLGGSGGVNAMLYVRGNRRDFDGWAAMGSTGWSYDQVMPFFEKSV 194
               .|.:.:.:...|||||::.|||..:|||.||||:..|::.|...|::||:|...:|:|:|:.
 Worm   102 ---TAQKNLGNRVFYWPRGRVWGGSSTLNAMCYVRGHAYDYNRWEKEGASGWNYANCLPYFKKAE 163

  Fly   195 TPQGNATHP-------KGYVTLKPFERKDNDIHQMIIDGGRELGQPYVERFQEGSDTGYSHVPGT 252
            | ..:||.|       .|.:.:|..: .:|.:|:..::.|:|....:..........|.|.:..|
 Worm   164 T-YSDATGPNDPYRGNNGPLYVKKGD-AENPLHKAWLNVGKEHPLGWTNDMNGEKQEGISTMDMT 226

  Fly   253 VRQGQRMSTGKGYLGAVSKSRPNLHVVKNALVTKLDLDGETVKEVKFER----AGV-------TH 306
            :..|:|.|..|.|:..: ::||||........|::..|......::|.|    .|.       ..
 Worm   227 IHNGERWSASKAYVHPI-RNRPNLITSSGITCTRVLFDTNKAIGIEFIRKLNFVGTDSIDSYSRE 290

  Fly   307 RVKVTKDVVISAGAIDSPALLLRSGIGPSKHLKELGIPVKLDLPGVGRNLQDHVLVPVFLRLDEG 371
            ::....||:::.|||::|.||:.||:||:.||:...||:..:|||||:|||||:.:.|    .:.
 Worm   291 KIYCQGDVILAGGAINTPQLLMLSGVGPADHLRSHEIPIVANLPGVGQNLQDHLEIYV----QQE 351

  Fly   372 QGEPMTDQAALDSIY----------------QYLIYRAGPLAAHSTASLVGFINTNASSDG--AY 418
            ..:|:|       :|                ::...|.| |.|.|.....||    |.||.  .:
 Worm   352 STQPVT-------LYNKSSWKFPHNMIKIGLEWFTNRTG-LGASSHLETGGF----ARSDDTVTH 404

  Fly   419 PDTENHHMFFQRAHHASLELFTKGLSIQDQYTEVLQEYLKDSHLLCVFVLLSHPAARGELRLKST 483
            ||.:.|  |.....|            .|..|.      ...|...|.|......::|.:.|::.
 Worm   405 PDIQFH--FLPSTVH------------DDGRTN------GTCHGYQVHVGPMRSQSKGYIMLQAK 449

  Fly   484 DPKVPPILTSNYLTESEDVATLMRGIRYIESLEQTKAFQDHLA-EIARIPIKECD-QIENYRSEE 546
            ||:..||:..||:.|..|.....:.||....|..:|||.:... |:|..|..:.| .|:.:..|:
 Worm   450 DPRRAPIINPNYMEEDSDWREFRKCIRVSRELFASKAFDEFRGKELAPGPDCQSDADIDRFVKEK 514

  Fly   547 YWRCYAKYFTVTCYHQSGTVKMGPDYDNEACVS-QRLKVHGLENLRVADASIMPAVVSANTNAAT 610
                     ..:.||.|.|.|||.:.|..|.|: :.:.|:|.|||:|.|||:||::||.|.||..
 Worm   515 ---------AASAYHPSCTCKMGSENDKMAVVNPETMGVYGTENLKVVDASVMPSIVSGNLNAPV 570

  Fly   611 VMIGERAAHFIQEDYQ 626
            :|:.||||..|:...|
 Worm   571 IMMAERAADLIKHKKQ 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fiz	NP_001285254.1	PRK02106	66..621	CDD:235000	182/594 (31%)
		NADB_Rossmann	70..>105	CDD:304358	18/32 (56%)
		NADB_Rossmann	142..359	CDD:304358	75/234 (32%)
		GMC_oxred_C	472..617	CDD:282984	50/147 (34%)
chdh-1	NP_495846.1	PRK02106	41..599	CDD:235000	184/601 (31%)
		NADB_Rossmann	41..>78	CDD:304358	20/39 (51%)
		NADB_Rossmann	108..345	CDD:304358	77/239 (32%)
		GMC_oxred_C	439..577	CDD:282984	50/146 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	94	1.000	Domainoid score	I4696
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm14159
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.690