DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9512 and AT5G51950

DIOPT Version :9

Sequence 1:	NP_001285253.1	Gene:	CG9512 / 32419	FlyBaseID:	FBgn0030593	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_200008.1	Gene:	AT5G51950 / 835270	AraportID:	AT5G51950	Length:	586	Species:	Arabidopsis thaliana

Alignment Length:	615	Identity:	169/615 - (27%)
Similarity:	251/615 - (40%)	Gaps:	143/615 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 YDFIVIGSGTSGAVVAGRLAEVKNWKVLLLEAGGDP---PIETEFVAWHMATQFSEWDWQYHSKP 119
            :|:|:||.||||..:|..|::  |..||:||.||.|   |..|:..  :.||..|      ::.|
plant    46 FDYIIIGGGTSGCALAATLSQ--NASVLVLERGGAPYDNPTATDIE--NFATTLS------NTSP 100

  Fly   120 NGRACMAMKGESCHWPRGKMLGGTNGMNAMIYARGTRKDFDDWEERGNPGWGYDEVLKHFRKAED 184
            ...:.:.:..:..:..|.::|||.:.:||..|.|...:...:.|      |..|||...:...|.
plant   101 KSWSQLFISEDGVYNTRARVLGGGSVLNAGFYTRAGDEYVKETE------WKTDEVEAAYEWVEK 159

  Fly   185 LRSTRPDYKPGDHGVGGPMGLNNYVSDNEFRTTIRAGMQEMGYGSAPDFTEGSFVGQMDILGTQD 249
            ..:.:|..          :|         ::|..:.|:.|.|     :|....|... .|.||:.
plant   160 KVAFQPPV----------LG---------WQTAFKDGLLEAG-----EFPYNGFTYD-HIYGTKI 199

  Fly   250 G-------GRRITTARSHLKKNTPNLHILRHAHVKKINLDRNNR----AESVTF------VHRGK 297
            |       |.|.|.|......|..|:.:..||.|.||......|    |..|.|      :|  |
plant   200 GGTIFDRAGHRHTAADLLEYANPGNIVVYLHASVHKILFTTKGRPRPKAYGVIFQDANGVLH--K 262

  Fly   298 KEYTVKASKEVIVSAGAIGSPQILLLSGIGPADHLKSLGI-PVKLDLP-VGENLKDHASLPM--I 358
            .|....:..|||:|||||||||:|:|||||||.||.:.|| |:.||.| ||:.:.|:   ||  |
plant   263 AELEKNSMNEVILSAGAIGSPQLLMLSGIGPAAHLAAHGIKPLVLDHPMVGQGMGDN---PMNAI 324

  Fly   359 FQIDKSTARKPTEEELVDAM-----YNLLMGRYSKLLHHEAT-----ALTGFIN------TTSIE 407
            | |...|   |.|..|:..:     .:.:.|....:..:..|     .:..::|      |||..
plant   325 F-IPSPT---PVEVSLIQVVGITKFESYIEGASGVIFSYSWTRRFFDGVLNYLNEMQTSRTTSTT 385

  Fly   408 GPNPDIQT-TNFFSLMQSPELKGYVAATGFNDRVAKSILSANQETNTYITYLLHLKPFSAGSLTL 471
            .|....|: |:||:.: :|.|.....|.....::|                    .|.|.|.|.|
plant   386 SPTLSTQSITDFFNPI-NPLLNATTRAGLILQKIA--------------------GPISRGHLEL 429

  Fly   472 QSANYLDAPIIDPGYMTDERDVDTYIRALNIYKNLPNTKAFSE---REAALH-KLDLEACNGLTY 532
            ::.|..|.|.:...|..:..|:...:..:|....:.|:||||:   .:|.:| .|||........
plant   430 RNTNPDDNPSVRFNYYQEPEDLQICVEGINTIIKVINSKAFSKFKYPDATIHGLLDLMLSVPTNL 494

  Fly   533 QSDDYWRCYIRHMTT-------------TVYHPVGTTRMGPSTDPTAVVDPQLRVHGAKGLRVID 584
            :.        ||:|:             |::|..|..::|      .|||...||.|...|||||
plant   495 RP--------RHITSMFNLRQFCIDTVMTIWHYHGGCQVG------RVVDKNYRVLGIDSLRVID 545

  Fly   585 ASIMPDIVGANTNAACIMIAEKGADMIKEE 614
            .|......|.|..|..:|:.......|.:|
plant   546 GSTFLKSPGTNPQATVMMLGRYMGQRILQE 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9512	NP_001285253.1	PRK02106	56..612	CDD:235000	167/611 (27%)
		NADB_Rossmann	120..352	CDD:304358	74/250 (30%)
		GMC_oxred_C	463..606	CDD:282984	44/159 (28%)
AT5G51950	NP_200008.1	PLN02785	10..576	CDD:215420	169/615 (27%)
		NADB_Rossmann	46..310	CDD:304358	95/306 (31%)
		GMC_oxred_C	421..565	CDD:282984	44/157 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D798314at2759
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		mtm950
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730