DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9512 and AT5G51930

DIOPT Version :9

Sequence 1:	NP_001285253.1	Gene:	CG9512 / 32419	FlyBaseID:	FBgn0030593	Length:	623	Species:	Drosophila melanogaster
Sequence 2:	NP_200006.1	Gene:	AT5G51930 / 835268	AraportID:	AT5G51930	Length:	582	Species:	Arabidopsis thaliana

Alignment Length:	594	Identity:	158/594 - (26%)
Similarity:	247/594 - (41%)	Gaps:	134/594 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 YDFIVIGSGTSGAVVAGRLAEVKNWKVLLLEAGGDP---PIETEFVAWHMATQFSEWDWQYHSKP 119
            :|:|:||.||:|..:|..|::  |..||:||.||.|   |..|:     |....:.   ..::.|
plant    73 FDYIIIGGGTAGCALAATLSQ--NASVLVLERGGSPYENPTATD-----MGNSVNT---LLNNTP 127

  Fly   120 NGRACMAMKGESCHWPRGKMLGGTNGMNAMIYARGTRKDFDDWEERGNPGWGYDEVLKHFRKAED 184
            |..:.:.:..:..:..|.::|||.:.:|...|:|..    :|:.|...  |..:||...:...|.
plant   128 NSWSQLFISEDGVYNTRPRVLGGGSVINGGFYSRAG----NDYVEEAE--WEMEEVEAAYEWVEK 186

  Fly   185 LRSTRPDYKPGDHGVGGPMGLNNYVSDNEFRTTIRAGMQEMGYGSAPD--FTEGSFVGQMDILGT 247
            .....|..                   .|::...:.|:.|.  |.:||  ||..      .|.||
plant   187 KLVFEPQV-------------------IEWQKAFKDGLLEA--GESPDNGFTYD------HIYGT 224

  Fly   248 QDGGRRIT------TARSHLKKNTPN-LHILRHAHVKKINLDRNNRAESVTFVHRG----KKEYT 301
            :.||....      ||.:.|:...|| :.:..||.|.|:..  ...|..|.|....    |....
plant   225 KIGGTIFDRAGHRHTAANLLEYANPNRIVVYLHASVHKVLF--TTEAYEVLFEDANGVFHKANLA 287

  Fly   302 VKASKEVIVSAGAIGSPQILLLSGIGPADHLKSLGI-PVKLDLP-VGENLKDHASLPMIFQIDKS 364
            .||:.|||:||||:||||:|:|||:|||.||::.|: |:.||.| ||:.:.|:   ||.|....|
plant   288 NKATNEVILSAGALGSPQLLMLSGVGPAVHLEAHGVNPLVLDQPMVGQGMADN---PMNFVAIPS 349

  Fly   365 TARKPTEEELVDAM-----YNLLMGRYSKLLHHEAT-----ALTGFINTTSIEGPNPDIQTTNFF 419
            .  :|.|..|:.|:     .:.:.|.....|..:.|     .:...:|.|| ...:..|.|.:..
plant   350 P--QPVELSLIQAVGITKFDSYIEGLSGLSLSFDITRRFFDGVLNLLNETS-HTTSRKILTQSIA 411

  Fly   420 SLMQSPELKGYVAATGFNDRVAKSILSANQETNTYITYLLHLK---PFSAGSLTLQSANYLDAPI 481
            .|::|.::|..|...|                     .|:..|   |.|.|.:.|::.|..|.|.
plant   412 VLLKSFDVKLEVRMNG---------------------GLIFQKVDGPASKGHMKLRNTNPRDNPS 455

  Fly   482 IDPGYMTDERDVDTYIRALNIYKNLPNTKAFSERE----AALHKLDLEACNGLTYQSDDYWRCYI 542
            :...|..:..|::..::.||....:.|:||||:.:    .|...|:|.....:..:.
plant   456 VTFNYYQEPEDLNKCVKGLNTIIRMINSKAFSKYKYPGVTARELLNLMLALPINLRP-------- 512

  Fly   543 RHMT-------------TTVYHPVGTTRMGPSTDPTAVVDPQLRVHGAKGLRVIDASIMPDIVGA 594
            ||:|             |:|:|..|..::|      .|||...:|.|..||||||.|......|.
plant   513 RHVTSAFNLKQFCIDTVTSVWHYHGGCQVG------KVVDKNYKVLGIDGLRVIDGSTFLKSPGT 571

  Fly   595 NTNAACIMI 603
            |..|..:|:
plant   572 NPQATVMML 580

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9512	NP_001285253.1	PRK02106	56..612	CDD:235000	158/594 (27%)
		NADB_Rossmann	120..352	CDD:304358	70/246 (28%)
		GMC_oxred_C	463..606	CDD:282984	43/158 (27%)
AT5G51930	NP_200006.1	BetA	70..582	CDD:225186	158/594 (27%)
		NADB_Rossmann	73..317	CDD:304358	82/288 (28%)
		GMC_oxred_C	437..581	CDD:282984	43/158 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D798314at2759
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		mtm950
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.730