DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9514 and AT1G14185

DIOPT Version :9

Sequence 1:	NP_572981.1	Gene:	CG9514 / 32418	FlyBaseID:	FBgn0030592	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_563939.1	Gene:	AT1G14185 / 837978	AraportID:	AT1G14185	Length:	503	Species:	Arabidopsis thaliana

Alignment Length:	580	Identity:	148/580 - (25%)
Similarity:	246/580 - (42%)	Gaps:	131/580 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 AYDFIIIGGGSAGTVLASRLSEIPHWKILLLEAGGHETEISDVPLL--SLYLHKSKMDW-KYRTQ 155
            ::|:|::|||:||..||:.|||  .:.:|::|.||  :...| ||:  ..|...|.::. :|.:.
plant    36 SFDYIVVGGGTAGCSLAATLSE--KYSVLVIERGG--SPFGD-PLVEDKKYYGYSLINTDEYSSV 95

  Fly   156 PQP-TACQAMKDKRCCWTRGKVLGGSSVLNTMLYIRGNKRDFDQWADFGNPGWSYEDILPYFRKS 219
            .|. |:...:|:.     ||:||||||.:|...|.|.:    |::..  ..||. :|::....|.
plant    96 AQSFTSVDGIKNH-----RGRVLGGSSAINGGFYSRAS----DEFVK--KAGWD-KDLVQESYKW 148

  Fly   220 EDQRNPYLARNKRYHGTGGLWTVQDAPYNTPIGPAFLQAG--EEMGYDIVDVNGEQQTGFGFYQF 282
            .:.:..::....|:...              :...||:||  ...||.:....|.:..|..|.|.
plant   149 VESKVVFMPELTRWQSI--------------VQFGFLEAGFYPYNGYSLEHTQGTKIGGSIFDQC 199

  Fly   283 NMRRGSRSSTAKSFLRPARLRPN-LHVALFSHVTKVLTDPHTKRATGVQFIR-DGRLQNVYATR- 344
            ..|..|.......       :|| :.|.|.:.|..::.|.:..||.||:|:. ||.....|...
plant   200 GKRHTSADLLGYG-------KPNCITVLLNATVKSIIFDANKTRAVGVRFMESDGNSSKSYKVHV 257

  Fly   345 -----EVILSAGAIGSPHLMMLSGIGHGEELGRVGIPLVQHLPGVGQNLQDHIAVGGIAFLIDYP 404
                 ||||:|||:|||.:::|||||....|....||::.:|..||:.:.|:.|   |:.|:|
plant   258 EQHRGEVILAAGALGSPQILLLSGIGPENHLNDFDIPVIVNLKEVGKQMSDNPA---ISLLVD-- 317

  Fly   405 ISIVMKRMVNINTALRYA--ITEDGPLTSSIGLEAVAFINTKYANASDDWPDMNFMMTSASVMSD 467
                           |::  :|.|.|...:| .|...||                  ..:.|:..
plant   318 ---------------RFSQNLTVDPPQVVAI-TEGFKFI------------------LQSLVLPT 348

  Fly   468 GGSQVKTAHGLTDEFYQEVFGEVNNRDVFGVFPMMLRPKSRGYIKLASKNPLRYPLLYHNYLTHP 532
            ..:..:||              ::.:..|        |||:|.:||.:.||...|.:..|||.:.
plant   349 NITTTRTA--------------ISAKIAF--------PKSKGRLKLNNTNPRENPSVTFNYLENK 391

  Fly   533 DDVNVLREGVKAAVAMGETQAMKRF-GARYWNKPVPNCKHLTLYTDDYWNCFIRQYTMTIYHMSG 596
            .|::..:|.|.....:..::.:..| |.:..:|.|..        |:....|..:...|.||..|
plant   392 ADLDACQEMVLHLQHVARSKTVTFFLGTQAQDKLVAG--------DEELKKFCIKNVRTYYHYHG 448

  Fly   597 TAKMGPPTDPWAVVDPQLRVYGIPGLRVIDASIMPAITNGNIHAPVVMIGE-KGADMIKQ 655
            ...:|      :||:.:.:|.|:..|||:|.|........|..|.|:|:|. :|..::|:
plant   449 GCVVG------SVVNEEYKVNGVKRLRVVDGSTFEESPGTNPMATVLMLGRYQGIKILKE 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9514	NP_572981.1	PRK02106	95..679	CDD:235000	148/579 (26%)
		NADB_Rossmann	96..>126	CDD:304358	13/29 (45%)
		NADB_Rossmann	167..391	CDD:304358	64/233 (27%)
		GMC_oxred_C	505..648	CDD:282984	40/144 (28%)
AT1G14185	NP_563939.1	PRK02106	35..492	CDD:235000	145/568 (26%)
		NAD_binding_8	41..99	CDD:290186	21/62 (34%)
		NADB_Rossmann	109..311	CDD:304358	65/229 (28%)
		GMC_oxred_C	364..492	CDD:282984	39/141 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I3423
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D798314at2759
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		mtm950
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.770