DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9514 and AgaP_AGAP012609

DIOPT Version :9

Sequence 1:	NP_572981.1	Gene:	CG9514 / 32418	FlyBaseID:	FBgn0030592	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	XP_001230448.2	Gene:	AgaP_AGAP012609 / 4578447	VectorBaseID:	AGAP012609	Length:	316	Species:	Anopheles gambiae

Alignment Length:	334	Identity:	129/334 - (38%)
Similarity:	175/334 - (52%)	Gaps:	45/334 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   336 RLQNVYATREVILSAGAIGSPHLMMLSGIGHGEELGRVGIPLVQHLPGVGQNLQDHIAVGGIAFL 400
            |:..|...:|.|:||||:.:|.|:||||||..|:|...||.:|..|| ||:|||||:.|
Mosquito     2 RVLEVKVRKETIVSAGAVNTPQLLMLSGIGQEEDLREHGIRIVSDLP-VGRNLQDHVMV------ 59

  Fly   401 IDYPISIVMKRM------VNINT---ALRYAITEDGPLTSSIGLEAVA-----FINTKYANASDD 451
               |:...:.|.      :|.|.   ...|.:..:||| |.||:.|..     ..:.|.:|.:..
Mosquito    60 ---PLFYCINRSSATDFDLNRNVIGHMYDYLMHRNGPL-SEIGINAFTGFYHHMYSRKRSNIAGR 120

  Fly   452 WPDMNFMMTSASVMSDGGSQVKTAHGLTDEFYQEVFGEVNNRDVFGVFPMMLRPKSRGYIKLASK 516
            |..|        :..||            .|...|....|..||.|.|.::|:|||.|.|:|.|.
Mosquito   121 WLRM--------MELDG------------PFSSSVTDANNEADVLGAFVILLKPKSWGRIRLQSG 165

  Fly   517 NPLRYPLLYHNYLTHPDDVNVLREGVKAAVAMGETQAMKRFGARYWNKPVPNCKHLTLYTDDYWN 581
            ...:.|.:...||||..|:..|.||::....:..|.|.|..........:|:|:.....::.||.
Mosquito   166 QIEQKPKIDAGYLTHRQDIETLIEGIRIHQDIMATDAAKSMEPEPVRIELPSCQDELYDSNAYWE 230

  Fly   582 CFIRQYTMTIYHMSGTAKMGPPTDPWAVVDPQLRVYGIPGLRVIDASIMPAITNGNIHAPVVMIG 646
            |:||:.|:|:||..||||||...||.|||||:|||.|:.||||:||||||.|.:||.:|.|:|||
Mosquito   231 CYIRELTLTLYHPVGTAKMGHSNDPDAVVDPRLRVKGVAGLRVVDASIMPDIVSGNTNAAVIMIG 295

  Fly   647 EKGADMIKQ 655
            ||.:|||||
Mosquito   296 EKASDMIKQ 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9514	NP_572981.1	PRK02106	95..679	CDD:235000	129/334 (39%)
		NADB_Rossmann	96..>126	CDD:304358
		NADB_Rossmann	167..391	CDD:304358	28/54 (52%)
		GMC_oxred_C	505..648	CDD:282984	65/142 (46%)
AgaP_AGAP012609	XP_001230448.2	NADB_Rossmann	<6..56	CDD:304358	27/50 (54%)
AgaP_AGAP012609	XP_001230448.2	GMC_oxred_C	154..298	CDD:282984	66/143 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820