Protein Alignment CG9514 and Chdh

DIOPT Version :9

• Sequence 1: NP_572981.1
• Gene: CG9514 / 32418
• FlyBaseID: FBgn0030592
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_942026.1
• Gene: Chdh / 290551
• RGDID: 735166
• Length: 599
• Species: Rattus norvegicus
• Alignment Length: 608
• Identity: 232/608 - (38%)
• Similarity: 318/608 - (52%)
• Gaps: 73/608 - (12%)

  Fly    95 YDFIIIGGGSAGTVLASRLSEIPHWKILLLEAGGHETEISDVPL---------LSLYLHKSKMDW 150
            |.||::|.||||.|||:||:|.|:.::||||||..:..:....|         |...|...|.:|
  Rat    46 YTFIVVGAGSAGCVLANRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVANLCDDKYNW 110

  Fly   151 KYRTQPQPTACQAMKDKRCCWTRGKVLGGSSVLNTMLYIRGNKRDFDQWADFGNPGWSYEDILPY 215
            .|.|:.||    .:..:...|.||:|.||||.||.|:||||:..|:::|...|..||.|...|||
  Rat   111 YYHTEAQP----GLDGRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHRQGAEGWDYAHCLPY 171

  Fly   216 FRKSEDQRNPYLARNKRYHGTGGLWTVQDAPYNTPIGPAFLQAGEEMGYDIV-DVNGEQQTGFGF 279
            |||::...   |..| .|.|..|...|.....|.|:..|||||..:.||... |:||.||.|||:
  Rat   172 FRKAQKHE---LGAN-MYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGW 232

  Fly   280 YQFNMRRGSRSSTAKSFLRPARLRPNLHVALFSHVTKVLTDPHTKRATGVQFIRDGRLQNVYATR 344
            ....:.:|.|.|||.::||||..||||...:.:.|::||.:  ..||.||::|:||:....|.:|
  Rat   233 MDMTIHQGKRWSTASAYLRPALSRPNLRAEVQTLVSRVLFE--GTRAVGVEYIKDGQSHKAYVSR 295

  Fly   345 EVILSAGAIGSPHLMMLSGIGHGEELGRVGIPLVQHLPGVGQNLQDHIAVGGIAFLIDYPISI-- 407
            |||||.|||.||.|:||||:|:.::|.::|||:|.||||||||||||:.: .|......||::
  Rat   296 EVILSGGAINSPQLLMLSGVGNADDLKKLGIPVVCHLPGVGQNLQDHLEI-YIQHACTQPITLHS 359

  Fly   408 VMK--RMVNINTALRYAITEDGPLTSSIGLEAVAFINTKYANASDDWPDMNFMMTSASVMSDGGS 470
            ..|  |.|.|.....:..|.||   ::..||...||.::   .....||:.|....:.|:..|..
  Rat   360 AQKPLRKVCIGLEWLWRFTGDG---ATAHLETGGFIRSR---PGVPHPDIQFHFLPSQVIDHGRK 418

  Fly   471 QVKTAHGLTDEFYQEVFGEVNNRDVFGVFPMMLRPKSRGYIKLASKNPLRYPLLYHNYLTHPDDV 535
            ..:      .|.||...|             .:|..|.|::||.|.||..:|::..|||:...||
  Rat   419 PTQ------QEAYQVHVG-------------TMRATSVGWLKLRSTNPQDHPMINPNYLSTETDV 464

  Fly   536 NVLREGVKAAVAMGETQAMKRFGARYWNKPVPNCKHLTLYTDDYWNCFIRQYTMTIYHMSGTAKM 600
            ...|:.||..   .|..|.:.| |.:..|.:....|  :.:|...:.|:|....:.||.|.|.||
  Rat   465 EDFRQCVKLT---REIFAQEAF-APFRGKELQPGSH--VQSDKEIDAFVRAKADSAYHPSCTCKM 523

  Fly   601 GPPTDPWAVVDPQLRVYGIPGLRVIDASIMPAITNGNIHAPVVMIGEKGADMIKQLWLTPTTAPV 665
            |.|:||.||||.|.||.|:..||||||||||::.:||::||.:||.||.||:||
  Rat   524 GQPSDPTAVVDQQTRVIGVENLRVIDASIMPSVVSGNLNAPTIMIAEKAADVIK----------- 577

  Fly   666 GVQGQGPSPRQGHNTSPAPPPRT 688
                  ..|..|....|...|:|
  Rat   578 ------GCPALGDENVPVYKPQT 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9514	NP_572981.1	PRK02106	95..679	CDD:235000	229/597 (38%)
		NADB_Rossmann	96..>126	CDD:304358	17/29 (59%)
		NADB_Rossmann	167..391	CDD:304358	106/224 (47%)
		GMC_oxred_C	505..648	CDD:282984	59/142 (42%)
Chdh	NP_942026.1	PRK02106	45..591	CDD:235000	230/603 (38%)
		NADB_Rossmann	49..>151	CDD:304358	43/105 (41%)
		GMC_oxred_N	121..344	CDD:279121	108/228 (47%)
		GMC_oxred_C	435..572	CDD:282984	60/142 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	244	1.000	Domainoid score	I2129
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	342	1.000	Inparanoid score	I2269
OMA	1	1.010	-	-		QHG52181
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm44531
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.780