DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9514 and AgaP_AGAP002552

DIOPT Version :9

Sequence 1:	NP_572981.1	Gene:	CG9514 / 32418	FlyBaseID:	FBgn0030592	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	XP_312387.5	Gene:	AgaP_AGAP002552 / 1273413	VectorBaseID:	AGAP002552	Length:	627	Species:	Anopheles gambiae

Alignment Length:	577	Identity:	253/577 - (43%)
Similarity:	361/577 - (62%)	Gaps:	7/577 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    81 PENRPFNVQQVDLAYDFIIIGGGSAGTVLASRLSEIPHWKILLLEAGGHETEISDVPLLSLYLHK 145
            |:.:.|..:     |||||||.||.|:|:|:||||:..|.:||||||.....:::|||.:.....
Mosquito    53 PDTKAFRKE-----YDFIIIGAGSGGSVMANRLSEVRDWNVLLLEAGKEGNMLTEVPLTAGLTTI 112

  Fly   146 SKMDWKYRTQPQPTACQAMKDKRCCWTRGKVLGGSSVLNTMLYIRGNKRDFDQWADFGNPGWSYE 210
            :..:|.|:..|...||..:|...|.|.:|:.|||:|::|.::|.||::.|:|.|...|||||.|.
Mosquito   113 TGYNWGYKADPMKGACLGLKGGVCNWPKGRGLGGTSLINFLIYTRGHRSDYDGWEQAGNPGWGYR 177

  Fly   211 DILPYFRKSEDQRNPYLARNKRYHGTGGLWTVQDAPYNTPIGPAFLQAGEEMGYDIVDVNGEQQT 275
            ::|.||:|||..:.|.| |:..|..|.||..|:::.:.||:...|::||.::||...|.|||.|.
Mosquito   178 EVLQYFKKSERVQIPEL-RHSPYRSTAGLVDVEESQFETPLLKRFIEAGRDLGYMETDPNGEIQL 241

  Fly   276 GFGFYQFNMRRGSRSSTAKSFLRPARLRPNLHVALFSHVTKVLTDPHTKRATGVQFIRDGRLQNV 340
            |||..|..||||.|.|.:|::|.||..||||.::::|.|||||.||.||.|.||:||:..|...:
Mosquito   242 GFGKAQATMRRGRRCSASKAYLVPASRRPNLDISMYSRVTKVLIDPVTKHAYGVEFIKRRRRYVI 306

  Fly   341 YATREVILSAGAIGSPHLMMLSGIGHGEELGRVGIPLVQHLPGVGQNLQDHIAVGGIAFLIDYPI 405
            .|.:||||:||||.||.|:||||:|..|.|..:|||:||.|| ||.|:|||:.:.|:.|.::.|:
Mosquito   307 RARKEVILAAGAIASPQLLMLSGVGPREHLKEMGIPVVQDLP-VGYNMQDHLNLPGLVFPVNQPV 370

  Fly   406 SIVMKRMVNINTALRYAITEDGPLTSSIGLEAVAFINTKYANASDDWPDMNFMMTSASVMSDGGS 470
            ::..:.|.:....:.|.:...||.||..|.|.|||:.|..:....|:||:..:|.:.:..:|...
Mosquito   371 TVRERDMRSPRPIIDYLVHGRGPFTSPGGAEGVAFVKTNISFTPSDYPDIELVMGTGAYNNDESG 435

  Fly   471 QVKTAHGLTDEFYQEVFGEVNNRDVFGVFPMMLRPKSRGYIKLASKNPLRYPLLYHNYLTHPDDV 535
            .::...|.||:||...:|.:..:..|.|.|:::||||||.|.|.|.||..:|.:..|:....||:
Mosquito   436 TLRATIGFTDQFYHSTYGSILGKHAFSVSPVLMRPKSRGRISLKSTNPFHWPRMEGNFFADYDDL 500

  Fly   536 NVLREGVKAAVAMGETQAMKRFGARYWNKPVPNCKHLTLYTDDYWNCFIRQYTMTIYHMSGTAKM 600
            .|||||||..|.:.|:::.:..|||..:.|...|:.....:|:||.|.||:...|:.|..||.||
Mosquito   501 LVLREGVKLTVDLIESRSFRDVGARLHSTPFYGCEQHRFRSDEYWECAIRRIGSTLQHQCGTCKM 565

  Fly   601 GPPTDPWAVVDPQLRVYGIPGLRVIDASIMPAITNGNIHAPVVMIGEKGADMIKQLW 657
            ||.|||.|||:|||:||||.||||:||||:|.|...:.:|.|.|||||.|||:|..|
Mosquito   566 GPVTDPEAVVNPQLQVYGIKGLRVVDASIIPTIPASHTNAVVFMIGEKAADMVKDFW 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9514	NP_572981.1	PRK02106	95..679	CDD:235000	251/563 (45%)
		NADB_Rossmann	96..>126	CDD:304358	19/29 (66%)
		NADB_Rossmann	167..391	CDD:304358	110/223 (49%)
		GMC_oxred_C	505..648	CDD:282984	70/142 (49%)
AgaP_AGAP002552	XP_312387.5	PRK02106	60..619	CDD:235000	249/565 (44%)
		NADB_Rossmann	138..357	CDD:304358	110/220 (50%)
		GMC_oxred_C	470..614	CDD:282984	71/143 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
TreeFam	0	0.000	Not matched by this tool.
	6	5.830