DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9514 and AgaP_AGAP003786

DIOPT Version :9

Sequence 1:	NP_572981.1	Gene:	CG9514 / 32418	FlyBaseID:	FBgn0030592	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	XP_310337.6	Gene:	AgaP_AGAP003786 / 1271523	VectorBaseID:	AGAP003786	Length:	665	Species:	Anopheles gambiae

Alignment Length:	604	Identity:	273/604 - (45%)
Similarity:	376/604 - (62%)	Gaps:	17/604 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 ILPFLIAAIAYYNYDLFDPENRPFNV--QQVDLAYDFIIIGGGSAGTVLASRLSEIPHWKILLLE 125
            ||..|.|.|.....|:.|..||..::  |.:...|||::|||||||...|:||||:..|.:||||
Mosquito    25 ILLILDACIWLQRTDVVDYRNRVQDIPSQFIYDVYDFVVIGGGSAGAAAAARLSEVCDWNVLLLE 89

  Fly   126 AGGHETEISDVPLLSLYLHKSKMDWKYRTQPQPTACQAMKDKRCCWTRGKVLGGSSVLNTMLYIR 190
            ||..|:.:||:|.|...|.|..:||::.|:|....||.|:..||.|.||||||||||||.|:|:|
Mosquito    90 AGTDESFLSDLPYLYPALQKGPLDWQFETEPNERFCQGMRGNRCSWPRGKVLGGSSVLNAMMYVR 154

  Fly   191 GNKRDFDQWADFGNPGWSYEDILPYFRKSEDQRNPYLARNKRYHGTGGLWTVQDAPYNTPIGPAF 255
            |:..|:|:||.|||.|||::|:||||.|.|:.|:|.:| .:.||||.|..||:.....:.:.|.|
Mosquito   155 GHPEDYDEWARFGNRGWSWQDVLPYFVKMENVRDPNIA-GRPYHGTTGPMTVELIRNRSALQPMF 218

  Fly   256 LQAGEEMGYDIVD-VNGEQQTGFGFYQFNMRRGSRSSTAKSFLRPARLRPNLHVALFSHVTKVLT 319
            |||.:|:|..:.| |||..|..|.....::|.|.|.||||::|||...|.|||:::.|.|.::|.
Mosquito   219 LQAAQELGMKLADEVNGPDQLVFAPLHGSIRDGLRCSTAKAYLRPIGNRKNLHISMNSMVERILI 283

  Fly   320 DPHTKRATGVQFIRDGRLQNVYATREVILSAGAIGSPHLMMLSGIGHGEELGRVGIPLVQHLPGV 384
            ||..:||.||.|.:..|.|.|..|:|::|||||:.||||:||||:|..::|.|.||.::..||||
Mosquito   284 DPKDRRAYGVVFRKGNRRQFVLVTKEIVLSAGALNSPHLLMLSGVGPRDQLQRHGIRVIHELPGV 348

  Fly   385 GQNLQDHIAVGGIAFLI-----DYPISIVMKRMVNINTALRYAITEDGPLTSSIGLEAVAFINTK 444
            |||||||:|.||..|||     ..|:||.:..:..::.|..:.....|.|.|....|.:.|||||
Mosquito   349 GQNLQDHVAAGGGVFLIQNPTGSAPLSIRLVEVNEVSVARDFLFRNQGRLLSMPSCEVMGFINTK 413

  Fly   445 YANASDDWPDMNFMMTSASVMSDGGSQVKTAHGLTDEFYQEVFGEVNNRDVFGVFPMMLRPKSRG 509
            |........|:...|::.|.:||||::.:...|||.|:|...|......|.|.:.|:::.|:|||
Mosquito   414 YNKPGSRRGDVQIFMSAQSDISDGGTEGQAGAGLTYEYYARNFESWVYHDSFLIMPLLMHPESRG 478

  Fly   510 YIKLASKNPLRYPLLYHNYLTHPDDVNVLREGVKAAVAMGETQAMKRFGARYWNKPVPNCKHLTL 574
            :::|.|.||:....:|.||.....|:::|.||:|..|.:.||..|::..|.:    :.:.:|...
Mosquito   479 WLELPSANPMDKIKIYPNYFAVERDLDILVEGLKFGVRVAETSVMRKINATF----IYDAEHGDT 539

  Fly   575 YT----DDYWNCFIRQYTMTIYHMSGTAKMGPPTDPWAVVDPQLRVYGIPGLRVIDASIMPAITN 635
            ..    |.::.|.|:.|:.||||.||||||||.|||.||||.||||:||.||||:||||||.||.
Mosquito   540 CNGQVGDAFFKCLIQHYSQTIYHPSGTAKMGPATDPMAVVDDQLRVHGIGGLRVVDASIMPKITT 604

  Fly   636 GNIHAPVVMIGEKGADMIK 654
            ||.:||.:||.|:.||:||
Mosquito   605 GNTNAPTIMIAERAADLIK 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9514	NP_572981.1	PRK02106	95..679	CDD:235000	263/570 (46%)
		NADB_Rossmann	96..>126	CDD:304358	18/29 (62%)
		NADB_Rossmann	167..391	CDD:304358	115/224 (51%)
		GMC_oxred_C	505..648	CDD:282984	69/146 (47%)
AgaP_AGAP003786	XP_310337.6	PRK02106	59..634	CDD:235000	263/570 (46%)
		NADB_Rossmann	130..357	CDD:304358	117/227 (52%)
		GMC_oxred_C	474..618	CDD:282984	70/147 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
TreeFam	0	0.000	Not matched by this tool.
	6	5.830