DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9518 and AT1G14185

DIOPT Version :9

Sequence 1:	NP_001285249.1	Gene:	CG9518 / 32416	FlyBaseID:	FBgn0030590	Length:	703	Species:	Drosophila melanogaster
Sequence 2:	NP_563939.1	Gene:	AT1G14185 / 837978	AraportID:	AT1G14185	Length:	503	Species:	Arabidopsis thaliana

Alignment Length:	587	Identity:	149/587 - (25%)
Similarity:	235/587 - (40%)	Gaps:	149/587 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 YDFIVVGSGSAGAVVANRLSEVRKWKVLLIEAG--PDENEISDVPSLAAYLQLSKLDWAYKTEPS 119
            :|:||||.|:||..:|..|||  |:.||:||.|  |..:.:.:......|..::..:::...:..
plant    37 FDYIVVGGGTAGCSLAATLSE--KYSVLVIERGGSPFGDPLVEDKKYYGYSLINTDEYSSVAQSF 99

  Fly   120 TKACLGMQNNRCNWPRGRVLGGSSVLNYMLYVRGNRHDYDHWASLGNPGWDYDNVLRYFKKSEDN 184
            |... |::|:     |||||||||.:|...|.|.:    |.:..  ..|||.|.|...:|..|..
plant   100 TSVD-GIKNH-----RGRVLGGSSAINGGFYSRAS----DEFVK--KAGWDKDLVQESYKWVESK 152

  Fly   185 RNPYLANNKYHGRGGLLTVQE-SPWHSPLVAAFVEAG--TQLGYDNRDINGAKQAGFMIAQGTIR 246
                           ::.:.| :.|.|.:...|:|||  ...||......|.|..|.:..|...|
plant   153 ---------------VVFMPELTRWQSIVQFGFLEAGFYPYNGYSLEHTQGTKIGGSIFDQCGKR 202

  Fly   247 RGS---------RCSTAKAFLRPIRMRKNFHLSMNSHVTRVIIEPGTMRAQAVEFVK----HGKV 298
            ..|         .|.|               :.:|:.|..:|.:....||..|.|::    ..|.
plant   203 HTSADLLGYGKPNCIT---------------VLLNATVKSIIFDANKTRAVGVRFMESDGNSSKS 252

  Fly   299 YRIAA---RREVIISAGAINTPQLMMLSGLGPRKHLEKHGIRVLQDL-PVGENMQDHVGMGGLTF 359
            |::..   |.|||::|||:.:||:::|||:||..||....|.|:.:| .||:.|.|
plant   253 YKVHVEQHRGEVILAAGALGSPQILLLSGIGPENHLNDFDIPVIVNLKEVGKQMSD--------- 308

  Fly   360 LVDKPVAIVQDRFNPTAVTFQYVLRERGPMTTLGGVEGLAFVHTPYSNRSLDWPDIQFHMAPASI 424
              :..::::.|||:.....        .|...:...||..|:             :|..:.|.:|
plant   309 --NPAISLLVDRFSQNLTV--------DPPQVVAITEGFKFI-------------LQSLVLPTNI 350

  Fly   425 NSDNGARVKKVLGLKESVYQEVYHPIANKDSWTIMPLLLRPRSRGSVKLRSANPFHYPLINANYF 489
            .:...|                           |...:..|:|:|.:||.:.||...|.:..||.
plant   351 TTTRTA---------------------------ISAKIAFPKSKGRLKLNNTNPRENPSVTFNYL 388

  Fly   490 DDPLDAKTLVEGAKIALRVAEAQVFKQFGSRLWRKPLPNCKQHKFLS-DAYLE--C--HVRTISM 549
            ::..|.....|.......||.::....|        |....|.|.:: |..|:  |  :||
plant   389 ENKADLDACQEMVLHLQHVARSKTVTFF--------LGTQAQDKLVAGDEELKKFCIKNVR---- 441

  Fly   550 TIYHPCGTAKMGPAWDPEAVVDPRLRVYGVRGLRVIDASIMPTISSGNTNAPVIMIAE-KGADLI 613
            |.||..|...:|      :||:...:|.||:.|||:|.|........|..|.|:|:.. :|..::
plant   442 TYYHYHGGCVVG------SVVNEEYKVNGVKRLRVVDGSTFEESPGTNPMATVLMLGRYQGIKIL 500

  Fly   614 KE 615
            ||
plant   501 KE 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9518	NP_001285249.1	PRK02106	56..614	CDD:235000	147/584 (25%)
		NADB_Rossmann	128..351	CDD:304358	69/242 (29%)
		GMC_oxred_C	465..608	CDD:282984	42/148 (28%)
AT1G14185	NP_563939.1	PRK02106	35..492	CDD:235000	146/575 (25%)
		NAD_binding_8	41..99	CDD:290186	18/59 (31%)
		NADB_Rossmann	109..311	CDD:304358	69/248 (28%)
		GMC_oxred_C	364..492	CDD:282984	42/145 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	69	1.000	Domainoid score	I3423
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D798314at2759
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		mtm950
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.860