Protein Alignment CG9518 and Chdh

DIOPT Version :9

• Sequence 1: NP_001285249.1
• Gene: CG9518 / 32416
• FlyBaseID: FBgn0030590
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_001129712.1
• Gene: Chdh / 218865
• MGIID: 1860776
• Length: 596
• Species: Mus musculus
• Alignment Length: 591
• Identity: 227/591 - (38%)
• Similarity: 315/591 - (53%)
• Gaps: 66/591 - (11%)

  Fly    56 EYDFIVVGSGSAGAVVANRLSEVRKWKVLLIEAGPDEN---------EISDVPSLAAYLQLSKLD 111
            ||.|:|||:||||.|:|:||:|....:|||:||||.:.         :|....:|.:.|...|.:
Mouse    42 EYTFVVVGAGSAGCVLASRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVSNLCDDKYN 106

  Fly   112 WAYKTEPSTKACLGMQNNRCNWPRGRVLGGSSVLNYMLYVRGNRHDYDHWASLGNPGWDYDNVLR 176
            |.|.|||..    ||.:....||||||.||||.||.|:|:||:..||:.|...|..||||.:.|.
Mouse   107 WYYHTEPQP----GMDSRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAEGWDYAHCLP 167

  Fly   177 YFKKSEDNRNPYLANNKYHGRGGLLTVQESPWHSPLVAAFVEAGTQLGYD-NRDINGAKQAGFMI 240
            ||:|::.:.   |..|.|.|..|.|.|.....:.||..||::|..|.||. ..|:||.:|.||..
Mouse   168 YFRKAQRHE---LGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGW 229

  Fly   241 AQGTIRRGSRCSTAKAFLRPIRMRKNFHLSMNSHVTRVIIEPGTMRAQAVEFVKHGKVYRIAARR 305
            ...|:.:|.|.|||.|:|.|:..|.|....:.:.|:||:.| || ||..||::|.|:.::....|
Mouse   230 MDMTVHQGKRWSTACAYLHPVLSRPNLRAEVQTLVSRVLFE-GT-RAVGVEYIKDGQRHKAYVSR 292

  Fly   306 EVIISAGAINTPQLMMLSGLGPRKHLEKHGIRVLQDLP-VGENMQDHVGMGGLTFLVD----KPV 365
            |||:|.||||:|||:||||:|....|.|..|.|:..|| ||:|:|||     |...|.    :|:
Mouse   293 EVILSGGAINSPQLLMLSGVGNADDLRKLDIPVVCHLPGVGQNLQDH-----LEVYVQQACTQPI 352

  Fly   366 AI--VQDRFNPTAVTFQYVLRERGPMTTLGGVEGLAFVHTPYSNRSLDWPDIQFHMAPASINSDN 428
            .:  .|.......:..:::....|...| ..:|...|:.   |...:..||||||..|:.: .|:
Mouse   353 TLHSAQKPLRKVCIGLEWLWSYTGDGAT-AHLETGGFIR---SRPGVPHPDIQFHFLPSQV-IDH 412

  Fly   429 GARVKKVLGLKESVYQEVYHPIANKDSWTIMPLLLRPRSRGSVKLRSANPFHYPLINANYFDDPL 493
            |         ::...||.|.         :....:|..|.|.:|||||||..:|:|:.||    |
Mouse   413 G---------RKPTQQEAYQ---------VHVGTMRATSVGWLKLRSANPRDHPVIHPNY----L 455

  Fly   494 DAKTLVEGAKIALRVAEAQVFKQFGSRLWRKPLPNCKQHKFLSDAYLECHVRTISMTIYHPCGTA 558
            ..:|.||..:..:|::. ::|.|.....:|........| ..||..::..||..:.:.|||..|.
Mouse   456 STETDVEDFRQCVRLSR-EIFAQEALAPFRGKELQPGSH-VQSDKEIDAFVRAKADSAYHPSCTC 518

  Fly   559 KMGPAWDPEAVVDPRLRVYGVRGLRVIDASIMPTISSGNTNAPVIMIAEKGADLIK-----EDWL 618
            |||.:.||.||||.:.:|.||..|||:||||||::.|||.|||.:|||||.||:||     || .
Mouse   519 KMGRSSDPTAVVDAQTKVIGVENLRVVDASIMPSVVSGNLNAPTVMIAEKAADIIKGHPALED-K 582

  Fly   619 TNPEYK 624
            ..|.||
Mouse   583 NVPVYK 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9518	NP_001285249.1	PRK02106	56..614	CDD:235000	220/574 (38%)
		NADB_Rossmann	128..351	CDD:304358	99/224 (44%)
		GMC_oxred_C	465..608	CDD:282984	60/142 (42%)
Chdh	NP_001129712.1	PRK02106	42..588	CDD:235000	225/589 (38%)
		NAD_binding_8	47..>76	CDD:290186	17/28 (61%)
		GMC_oxred_N	118..341	CDD:279121	101/232 (44%)
		GMC_oxred_C	432..569	CDD:282984	61/142 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	241	1.000	Domainoid score	I2232
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	336	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm42468
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.860