Protein Alignment CG9518 and chdh-1

DIOPT Version :9

• Sequence 1: NP_001285249.1
• Gene: CG9518 / 32416
• FlyBaseID: FBgn0030590
• Length: 703
• Species: Drosophila melanogaster
• Sequence 2: NP_495846.1
• Gene: chdh-1 / 174390
• WormBaseID: WBGene00007917
• Length: 599
• Species: Caenorhabditis elegans
• Alignment Length: 590
• Identity: 216/590 - (36%)
• Similarity: 314/590 - (53%)
• Gaps: 83/590 - (14%)

  Fly    60 IVVGSGSAGAVVANRLSEVRKWKVLLIEAGPDENEIS---DVPSLAAY-LQLSKLDWAYKTEPST 120
            |:||:||||.|:||||:|....:||||||||.:::..   .:|:...| |.....:|.|.|  :.
 Worm    41 IIVGAGSAGCVLANRLTEDPSNRVLLIEAGPVDHKWDWRIHMPAALMYNLCSDTYNWHYHT--TA 103

  Fly   121 KACLGMQNNRCNWPRGRVLGGSSVLNYMLYVRGNRHDYDHWASLGNPGWDYDNVLRYFKKSEDNR 185
            :..||  |....||||||.||||.||.|.||||:.:||:.|...|..||:|.|.|.||||:|...
 Worm   104 QKNLG--NRVFYWPRGRVWGGSSTLNAMCYVRGHAYDYNRWEKEGASGWNYANCLPYFKKAETYS 166

  Fly   186 NPYLANNKYHGRGGLLTVQESPWHSPLVAAFVEAGTQ--LGYDNRDINGAKQAGFMIAQGTIRRG 248
            :....|:.|.|..|.|.|::....:||..|::..|.:  ||:.| |:||.||.|......||..|
 Worm   167 DATGPNDPYRGNNGPLYVKKGDAENPLHKAWLNVGKEHPLGWTN-DMNGEKQEGISTMDMTIHNG 230

  Fly   249 SRCSTAKAFLRPIRMRKNFHLSMNSHVTRVIIEPGTMRAQAVEFVK--------------HGKVY 299
            .|.|.:||::.|||.|.|...|.....|||:.:  |.:|..:||::              ..|:|
 Worm   231 ERWSASKAYVHPIRNRPNLITSSGITCTRVLFD--TNKAIGIEFIRKLNFVGTDSIDSYSREKIY 293

  Fly   300 RIAARREVIISAGAINTPQLMMLSGLGPRKHLEKHGIRVLQDLP-VGENMQDHVGMGGLTFLVD- 362
               .:.:||::.||||||||:||||:||..||..|.|.::.:|| ||:|:|||     |...|.
 Worm   294 ---CQGDVILAGGAINTPQLLMLSGVGPADHLRSHEIPIVANLPGVGQNLQDH-----LEIYVQQ 350

  Fly   363 ---KPVAIVQDRFNPTAVTFQYVLRERG-----PMTTLGGVEGLAFVHTPYSNRSLDWPDIQFHM 419
               :||.:    :|.::..|.:.:.:.|     ..|.||....|.......|:.::..||||||.
 Worm   351 ESTQPVTL----YNKSSWKFPHNMIKIGLEWFTNRTGLGASSHLETGGFARSDDTVTHPDIQFHF 411

  Fly   420 APASINSD---NGARVKKVLGLKESVYQEVYHPIANKDSWTIMPLLLRPRSRGSVKLRSANPFHY 481
            .|::::.|   ||..         ..||....|             :|.:|:|.:.|::.:|...
 Worm   412 LPSTVHDDGRTNGTC---------HGYQVHVGP-------------MRSQSKGYIMLQAKDPRRA 454

  Fly   482 PLINANYFDDPLDAKTLVEGAKIALRVAEAQVFKQF-GSRLWRKPLPNCKQHKFLSDAYLECHVR 545
            |:||.||.::..|.:...:..:::..:..::.|.:| |..|  .|.|:|:     |||.::..|:
 Worm   455 PIINPNYMEEDSDWREFRKCIRVSRELFASKAFDEFRGKEL--APGPDCQ-----SDADIDRFVK 512

  Fly   546 TISMTIYHPCGTAKMGPAWDPEAVVDPR-LRVYGVRGLRVIDASIMPTISSGNTNAPVIMIAEKG 609
            ..:.:.|||..|.|||...|..|||:|. :.|||...|:|:|||:||:|.|||.||||||:||:.
 Worm   513 EKAASAYHPSCTCKMGSENDKMAVVNPETMGVYGTENLKVVDASVMPSIVSGNLNAPVIMMAERA 577

  Fly   610 ADLIK 614
            |||||
 Worm   578 ADLIK 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9518	NP_001285249.1	PRK02106	56..614	CDD:235000	214/588 (36%)
		NADB_Rossmann	128..351	CDD:304358	99/239 (41%)
		GMC_oxred_C	465..608	CDD:282984	54/144 (38%)
chdh-1	NP_495846.1	PRK02106	41..599	CDD:235000	216/590 (37%)
		NADB_Rossmann	41..>78	CDD:304358	21/36 (58%)
		NADB_Rossmann	108..345	CDD:304358	102/249 (41%)
		GMC_oxred_C	439..577	CDD:282984	55/144 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	214	1.000	Domainoid score	I1583
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	310	1.000	Inparanoid score	I1553
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm14159
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.870