Protein Alignment CG9519 and Chdh

DIOPT Version :9

• Sequence 1: NP_572978.1
• Gene: CG9519 / 32415
• FlyBaseID: FBgn0030589
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_001129712.1
• Gene: Chdh / 218865
• MGIID: 1860776
• Length: 596
• Species: Mus musculus
• Alignment Length: 618
• Identity: 217/618 - (35%)
• Similarity: 303/618 - (49%)
• Gaps: 134/618 - (21%)

  Fly    61 KYDFIVVGAGTAGCALAARLSENPRWRVLLLEAGGPENYAM---------DIP--IVAHLLQLGE 114
            :|.|:|||||:|||.||:||:|:|..||||||| ||::..|         .:|  :|::|.. .:
Mouse    42 EYTFVVVGAGSAGCVLASRLTEDPNHRVLLLEA-GPKDLLMGSKRLQWKIHMPAALVSNLCD-DK 104

  Fly   115 INWKYKTEPSNSYCLAMNNNRCNWPRGKVMGGSSVLNYMMYTRGNRRDYDRWARLGNPGWSYEEV 179
            .||.|.|||..    .|::....||||:|.||||.||.|:|.||:..||:||.|.|..||.|...
Mouse   105 YNWYYHTEPQP----GMDSRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAEGWDYAHC 165

  Fly   180 LPYFKKYEGSVVPDADENLVGRN------GPVKVSYSETRTRIADAFVGATQDAGLP-RGDYNGD 237
            ||||:|        |..:.:|.|      ||:.||..:|...:..||:.|.:.||.| ..|.||.
Mouse   166 LPYFRK--------AQRHELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGF 222

  Fly   238 KQIRVSYLQANIYNETRWSSNRAYLYPIKGKRRNLHVKKNALVTKILIDPQTKSAFGIIVKMDGK 302
            :|....::...::...|||:..|||:|:. .|.||..:...||:::|.  :...|.|:....||:
Mouse   223 QQEGFGWMDMTVHQGKRWSTACAYLHPVL-SRPNLRAEVQTLVSRVLF--EGTRAVGVEYIKDGQ 284

  Fly   303 MQKILARKEVILSAGAINTPQLLMLSGVGPAKHLREMGIKPLADL-AVGYNLQDHIAPAISFLCN 366
            ..|....:|||||.||||:||||||||||.|..||::.|..:..| .||.|||||:...:...|.
Mouse   285 RHKAYVSREVILSGGAINSPQLLMLSGVGNADDLRKLDIPVVCHLPGVGQNLQDHLEVYVQQACT 349

  Fly   367 VS-SLQTSE--------------MFRSEAMSDFLKGRGVLRIPGGV--EAISFY-----ALDDAR 409
            .. :|.:::              .:..:..:..|:..|.:|...||  ..|.|:     .:|..|
Mouse   350 QPITLHSAQKPLRKVCIGLEWLWSYTGDGATAHLETGGFIRSRPGVPHPDIQFHFLPSQVIDHGR 414

  Fly   410 NPDAWADMELFVVGGGLQTNLALRLALGIQSNIYETMFGELERQSANGFLIFPMILRAKSRGRIK 474
            .|                          .|...|:...|               .:||.|.|.:|
Mouse   415 KP--------------------------TQQEAYQVHVG---------------TMRATSVGWLK 438

  Fly   475 LKSRNPEEHPRIYANYFANPYDMNITVRGIEQAVSL-LDMPAFKAI----------GAHL-LEKR 527
            |:|.||.:||.|:.||.:...|    |....|.|.| .::.|.:|:          |:|: .:|.
Mouse   439 LRSANPRDHPVIHPNYLSTETD----VEDFRQCVRLSREIFAQEALAPFRGKELQPGSHVQSDKE 499

  Fly   528 IPNCAKYKWKSSAYWACYARHFTFTIYHYSGTAKMGPRSDPSAVVDARLRVHGIDKLRVVDASIM 592
            |....:.|..|:              ||.|.|.|||..|||:|||||:.:|.|::.|||||||||
Mouse   500 IDAFVRAKADSA--------------YHPSCTCKMGRSSDPTAVVDAQTKVIGVENLRVVDASIM 550

  Fly   593 PYLISGHPNGPVYLIAEKAADMIK-----EDHN 620
            |.::||:.|.|..:|||||||:||     ||.|
Mouse   551 PSVVSGNLNAPTVMIAEKAADIIKGHPALEDKN 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9519	NP_572978.1	PRK02106	59..616	CDD:235000	212/607 (35%)
		NADB_Rossmann	63..>99	CDD:304358	24/35 (69%)
		NADB_Rossmann	132..356	CDD:304358	94/231 (41%)
		GMC_oxred_C	468..611	CDD:282984	59/154 (38%)
Chdh	NP_001129712.1	PRK02106	42..588	CDD:235000	217/618 (35%)
		NAD_binding_8	47..>76	CDD:290186	21/29 (72%)
		GMC_oxred_N	118..341	CDD:279121	96/233 (41%)
		GMC_oxred_C	432..569	CDD:282984	59/154 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	241	1.000	Domainoid score	I2232
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	336	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm42468
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.770