Protein Alignment CG9519 and chdh-1

DIOPT Version :9

• Sequence 1: NP_572978.1
• Gene: CG9519 / 32415
• FlyBaseID: FBgn0030589
• Length: 622
• Species: Drosophila melanogaster
• Sequence 2: NP_495846.1
• Gene: chdh-1 / 174390
• WormBaseID: WBGene00007917
• Length: 599
• Species: Caenorhabditis elegans
• Alignment Length: 620
• Identity: 201/620 - (32%)
• Similarity: 295/620 - (47%)
• Gaps: 112/620 - (18%)

  Fly    50 ENLDEG----QVITTKYDFIVVGAGTAGCALAARLSENPRWRVLLLEAGGPENYAMDIPI----- 105
            :::.||    .:...|...|:||||:|||.||.||:|:|..||||:|| ||.::..|..|
 Worm    22 DSMKEGTFSADIAENKPTHIIVGAGSAGCVLANRLTEDPSNRVLLIEA-GPVDHKWDWRIHMPAA 85

  Fly   106 VAHLLQLGEINWKYKTEPSNSYCLAMNNNRCNWPRGKVMGGSSVLNYMMYTRGNRRDYDRWARLG 170
            :.:.|.....||.|.|....:    :.|....||||:|.||||.||.|.|.||:..||:||.:.|
 Worm    86 LMYNLCSDTYNWHYHTTAQKN----LGNRVFYWPRGRVWGGSSTLNAMCYVRGHAYDYNRWEKEG 146

  Fly   171 NPGWSYEEVLPYFKK---YEGSVVPDADENLVGRNGPVKVSYSETRTRIADAFVGATQDAGLPRG 232
            ..||:|...||||||   |..:..|  ::...|.|||:.|...:....:..|::...::.  |.|
 Worm   147 ASGWNYANCLPYFKKAETYSDATGP--NDPYRGNNGPLYVKKGDAENPLHKAWLNVGKEH--PLG 207

  Fly   233 ---DYNGDKQIRVSYLQANIYNETRWSSNRAYLYPIKGKRRNLHVKKNALVTKILIDPQTKSAFG 294
               |.||:||..:|.:...|:|..|||:::||::||: .|.||........|::|.|  |..|.|
 Worm   208 WTNDMNGEKQEGISTMDMTIHNGERWSASKAYVHPIR-NRPNLITSSGITCTRVLFD--TNKAIG 269

  Fly   295 I-------IVKMDG----KMQKILARKEVILSAGAINTPQLLMLSGVGPAKHLREMGIKPLADL- 347
            |       .|..|.    ..:||..:.:|||:.|||||||||||||||||.|||...|..:|:|
 Worm   270 IEFIRKLNFVGTDSIDSYSREKIYCQGDVILAGGAINTPQLLMLSGVGPADHLRSHEIPIVANLP 334

  Fly   348 AVGYNLQDHIAPAISFLCNVSSLQTSEMFRSEAMSDFLKGRGVLRIPGGVEAISFYALDDARNPD 412
            .||.|||||:                |::..:.               ..:.::.|      |..
 Worm   335 GVGQNLQDHL----------------EIYVQQE---------------STQPVTLY------NKS 362

  Fly   413 AWA-DMELFVVGGGLQTNLALRLALGIQSNIYETMFGELE-----------------------RQ 453
            :|. ...:..:|....||   |..||..|::....|...:                       ..
 Worm   363 SWKFPHNMIKIGLEWFTN---RTGLGASSHLETGGFARSDDTVTHPDIQFHFLPSTVHDDGRTNG 424

  Fly   454 SANGFLIFPMILRAKSRGRIKLKSRNPEEHPRIYANYFANPYDMNITVRGIEQAVSLLDMPAFKA 518
            :.:|:.:....:|::|:|.|.|::::|...|.|..||.....|.....:.|..:..|....||..
 Worm   425 TCHGYQVHVGPMRSQSKGYIMLQAKDPRRAPIINPNYMEEDSDWREFRKCIRVSRELFASKAFDE 489

  Fly   519 I-GAHLLEKRIPNCAKYKWKSSAYWACYARHFTFTIYHYSGTAKMGPRSDPSAVVDAR-LRVHGI 581
            . |..|...  |:|     :|.|....:.:....:.||.|.|.|||..:|..|||:.. :.|:|.
 Worm   490 FRGKELAPG--PDC-----QSDADIDRFVKEKAASAYHPSCTCKMGSENDKMAVVNPETMGVYGT 547

  Fly   582 DKLRVVDASIMPYLISGHPNGPVYLIAEKAADMIK 616
            :.|:|||||:||.::||:.|.||.::||:|||:||
 Worm   548 ENLKVVDASVMPSIVSGNLNAPVIMMAERAADLIK 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9519	NP_572978.1	PRK02106	59..616	CDD:235000	197/605 (33%)
		NADB_Rossmann	63..>99	CDD:304358	22/35 (63%)
		NADB_Rossmann	132..356	CDD:304358	100/241 (41%)
		GMC_oxred_C	468..611	CDD:282984	48/144 (33%)
chdh-1	NP_495846.1	PRK02106	41..599	CDD:235000	198/601 (33%)
		NADB_Rossmann	41..>78	CDD:304358	22/37 (59%)
		NADB_Rossmann	108..345	CDD:304358	102/259 (39%)
		GMC_oxred_C	439..577	CDD:282984	48/144 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	214	1.000	Domainoid score	I1583
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	310	1.000	Inparanoid score	I1553
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm14159
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.780