DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9521 and AT1G73050

DIOPT Version :9

Sequence 1:	NP_572977.1	Gene:	CG9521 / 32414	FlyBaseID:	FBgn0030588	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_177448.1	Gene:	AT1G73050 / 843636	AraportID:	AT1G73050	Length:	552	Species:	Arabidopsis thaliana

Alignment Length:	616	Identity:	159/616 - (25%)
Similarity:	235/616 - (38%)	Gaps:	162/616 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 FLR--RGQADVELENYDNNVILDSEYDFIVVGAGTAGCALAARLSENPQWRVLLLEAGGPERLVM 99
            |:|  ....|...|:|         ||:|:||.|||||.|||.||::  :||||||.||
plant    38 FMRFISNATDFASEDY---------YDYIIVGGGTAGCPLAATLSQS--FRVLLLERGG------ 85

  Fly   100 DVP-----IVAH--FL-QLGEMNWKYRTQPSDHACLAMNNNRCNWPRGKVMGGSSVLNYMMYTRG 156
             ||     :::|  || .|.::|     .....|...::.......||:|:||||.:|...|:|.
plant    86 -VPYNRPNVMSHDGFLTTLTDVN-----NFDSPAQSFISEEGVPNARGRVLGGSSAINAGFYSRA 144

  Fly   157 NRRDYDRWEALGNPG--WSFKDVLPYFKKYEGSSVPDAEEDYVGRNGPVKVSYVNWRSKIAEAFV 219
            :::.::      |.|  |..            |||..:.| :|.|....:.....|::.|.:|.:
plant   145 DKQFFE------NSGLVWDL------------SSVNQSYE-WVERAIVFRPQLRTWQTAIRDALL 190

  Fly   220 DAAQQDGLKYRDYNGRIQNGVAFLH---------TTTRNSTRWSSNRAYLYPLKGKRSNLHVRKN 275
            :.....           .||....|         |..|...|.||.....|   .:.||:.|...
plant   191 EVGVHP-----------FNGFTLEHKVGTKIGGSTFDRTGRRHSSADLLRY---ARSSNIRVAVY 241

  Fly   276 ALVTKVLI--DPQTK----TAYGIMVQTE-GRMQKILARK--EVIVSAGAINTPQLLMLSGVGPA 331
            |.|.:||:  .|...    :|.|::.:.: ||....|.|.  |||:||||:.:||||.|||:||.
plant   242 ATVERVLLASSPSVSGSNVSAIGVVYRDQLGRFHHALIRDRGEVILSAGALGSPQLLFLSGIGPR 306

  Fly   332 KHLREVGIKPLADLAVGYNLQDHTAPAVTFTTNATSLKFEDFSDPTLINRFNRMEGPYGSP-GGC 395
            .:|...||....|       |.|....|                             |.:| .|.
plant   307 SYLSTWGIPVALD-------QPHVGDFV-----------------------------YDNPRNGI 335

  Fly   396 EAIAFWDLDHER------DEDGWPDIELFLVGGSMSSNPAISRAFGLKKSIYDTLF-AEIEDKSL 453
            ..:....:::..      .|||     .||        .|.|........::.... |......:
plant   336 SIVPPVPMENSLIQVVGVTEDG-----AFL--------EAASNVIPFASPLHSVFIRAPASPLYV 387

  Fly   454 NAFMIFPMILRPKSRGRIMLKSSDPFKYPLIHANYFAHPYDVDISVRGLLKAISLMEQRGMEKIN 518
            ....|...||.|.|.|.:.|.|:|....|::..|||:.|.|::..|.|..|...::..|.|:...
plant   388 PVTTIMEKILGPVSIGLLRLASTDVRINPVVRFNYFSDPQDLERCVNGTRKIGEILRSRAMQDFM 452

  Fly   519 ARLW---------EKKIPTCKQHPYKSWAYWACYVRHFTFTIYHYSGTAKMGPKSDRAAVVDHRL 574
            .|.|         ...:|..:.:.    ...|.:.|....||:||.|.|.:|      .|||..|
plant   453 IREWFGNRRFRFVGAPLPVDQSND----LVMADFCRRTVSTIWHYHGGAVVG------KVVDSDL 507

  Fly   575 RVHGIKNLRVADASIMPEIMSGHPNGPVFMI 605
            :|.|:.:||:.|.|........:|...:.|:
plant   508 KVIGVNSLRLVDGSTFNISPGTNPQATLMML 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9521	NP_572977.1	PRK02106	57..614	CDD:235000	154/594 (26%)
		NADB_Rossmann	61..>92	CDD:304358	20/30 (67%)
		NADB_Rossmann	125..356	CDD:304358	68/250 (27%)
		GMC_oxred_C	465..609	CDD:282984	41/150 (27%)
AT1G73050	NP_177448.1	PLN02785	30..551	CDD:215420	159/616 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H122489
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D798314at2759
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		mtm950
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.770