DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9521 and HTH

DIOPT Version :9

Sequence 1:	NP_572977.1	Gene:	CG9521 / 32414	FlyBaseID:	FBgn0030588	Length:	621	Species:	Drosophila melanogaster
Sequence 2:	NP_565050.1	Gene:	HTH / 843628	AraportID:	AT1G72970	Length:	594	Species:	Arabidopsis thaliana

Alignment Length:	592	Identity:	146/592 - (24%)
Similarity:	245/592 - (41%)	Gaps:	119/592 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 DSEYDFIVVGAGTAGCALAARLSENPQWRVLLLEAGGPERLVMDVPIVAHF-LQLGEMNWKYRTQ 120
            ||.||:||:|.|||||.|||.||:|  :.||:||.||......:|..:.:| :.|.:::....:|
plant    60 DSSYDYIVIGGGTAGCPLAATLSQN--FSVLVLERGGVPFTNANVSFLRNFHIGLADISASSASQ 122

  Fly   121 PSDHACLAMNNNRCNWPRGKVMGGSSVLNYMMYTRGNRRDYDRWEALGNPGWSFKDVLPYFKKYE 185
                 .....:...| .|.:|:||.|.:|...|:|.:.....|      .||.        .|..
plant   123 -----AFVSTDGVYN-ARARVLGGGSCINAGFYSRADAAFVKR------AGWD--------PKLV 167

  Fly   186 GSSVPDAEEDYVGRNGPVKVSYVNWRSKIAEAFVDAAQQ--DGLKYRDYNGRIQNGVAFLHTTTR 248
            ..|.|..|.:.|.:   .|::.  |:..:.::.::...:  :|..|...:|....|..|.....|
plant   168 KESYPWVEREIVHQ---PKLTL--WQKALRDSLLEVGVRPFNGFTYDHVSGTKIGGTIFDRFGRR 227

  Fly   249 NSTRWSSNRAYLYPLKGKRSNLHVRKNALVTKVLID-----PQTKTAYGIMVQTE--GRMQKILA 306
            ::.  :...||..|.|     |.|...|.|.|::.|     |:..   |::.:.|  .:.|.:|:
plant   228 HTA--AELLAYANPQK-----LRVLIYATVQKIVFDTSGTRPRVT---GVIFKDEKGNQHQALLS 282

  Fly   307 RK---EVIVSAGAINTPQLLMLSGVGPAKHLREVGIK-PLADLAVGYNLQDHTAPAVTFTTNATS 367
            .:   |||:|:|||.:||:|||||:||.|.|:.:.|. .|.:..||..:.|:....:...:.|.
plant   283 NRKGSEVILSSGAIGSPQMLMLSGIGPKKELQRLKIPVVLENEHVGKGMADNPMNTILVPSKAP- 346

  Fly   368 LKFEDFSDPTLINRFN------RMEGPYGSPGGCEAI-AFWDLDHERDEDGWPDIELFLVGGSMS 425
                  .:.:||....      .:|...|.....|:| ..:.:...::       |||....:..
plant   347 ------IEQSLIQTVGITKMGVYVEASTGFGQSPESIHTHYGIMSNKN-------ELFSTIPAKQ 398

  Fly   426 SNPAISRAFGLKKSIYDTLFAEIEDKSLNAFMIFPMILRPKSRGRIMLKSSDPFKYPLIHANYFA 490
            ..|..::|: :.::.|..      .::.|...|...:..|.|||.:.|.:::....|.:..|||.
plant   399 RRPEATQAY-ITRNKYQL------HEAFNGSFILEKLAYPISRGHLSLVNTNVDDNPSVTFNYFK 456

  Fly   491 HPYDVDISVRGLLKAISLM---------------EQRGMEKI-------NARLWEKKIPTCKQHP 533
            ||.|:...|    :||.|:               :::.:.|:       |..|..|::...|.
plant   457 HPVDLQRCV----EAIRLVSKVVTSNRFLNYTQCDKQNVHKMLSLSVKANINLRPKQLNDTKS-- 515

  Fly   534 YKSWAYWACYVRHFTFTIYHYSGTAKMGPKSDRAAVVDHRLRVHGIKNLRVADASIMPEIMSGHP 598
                  .|.:.:....||:||.|...:|      .||....:|.|:..|||.|.|...|....:|
plant   516 ------MAQFCKDTVVTIWHYHGGCLVG------KVVSPNRKVLGVDRLRVIDGSTFDESPGTNP 568

  Fly   599 NGPVFMI 605
            ...:.|:
plant   569 QATMMMM 575

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9521	NP_572977.1	PRK02106	57..614	CDD:235000	146/592 (25%)
		NADB_Rossmann	61..>92	CDD:304358	19/30 (63%)
		NADB_Rossmann	125..356	CDD:304358	63/243 (26%)
		GMC_oxred_C	465..609	CDD:282984	40/163 (25%)
HTH	NP_565050.1	PLN02785	18..594	CDD:215420	146/592 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	163	1.000	Inparanoid score	I1608
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D798314at2759
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		mtm950
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.770