Protein Alignment CG9521 and CHDH

DIOPT Version :10

• Sequence 1: NP_572977.1
• Gene: CG9521 / 32414
• FlyBaseID: FBgn0030588
• Length: 621
• Species: Drosophila melanogaster
• Sequence 2: NP_060867.2
• Gene: CHDH / 55349
• HGNCID: 24288
• Length: 594
• Species: Homo sapiens
• Alignment Length: 599
• Identity: 205/599 - (34%)
• Similarity: 286/599 - (47%)
• Gaps: 109/599 - (18%)

  Fly    59 EYDFIVVGAGTAGCALAARLSENPQWRVLLLEAG------GPERLV----MDVPIVAHFLQLGEM 113
            ||.::|||||:|||.||.||:|:|..||||||||      |.:||.    |...:||:... ...
Human    40 EYSYVVVGAGSAGCVLAGRLTEDPAERVLLLEAGPKDVLAGSKRLSWKIHMPAALVANLCD-DRY 103

  Fly   114 NWKYRTQPSDHACLAMNNNRCNWPRGKVMGGSSVLNYMMYTRGNRRDYDRWEALGNPGWSFKDVL 178
            ||.|.|:..    ..::.....||||:|.||||.||.|:|.||:..||:||:..|..||.:...|
Human   104 NWCYHTEVQ----RGLDGRVLYWPRGRVWGGSSSLNAMVYVRGHAEDYERWQRQGARGWDYAHCL 164

  Fly   179 PYFKKYEGSSVPDAEEDYVGRNGPVKVSYVNWRSKIAEAFVDAAQQDGLKY-RDYNGRIQNGVAF 242
            |||:|.:|..:  ....|.|.:||::||.......:..||::|.||.|... .|.||..|.|..:
Human   165 PYFRKAQGHEL--GASRYRGADGPLRVSRGKTNHPLHCAFLEATQQAGYPLTEDMNGFQQEGFGW 227

  Fly   243 LHTTTRNSTRWSSNRAYLYPLKGKRSNLHVRKNALVTKVLIDPQTKTAYGIMVQTEGRMQKILAR 307
            :..|.....|||:..|||:|.. .|:||......||::||.  :...|.|:.....|:..:..|.
Human   228 MDMTIHEGKRWSAACAYLHPAL-SRTNLKAEAETLVSRVLF--EGTRAVGVEYVKNGQSHRAYAS 289

  Fly   308 KEVIVSAGAINTPQLLMLSGVGPAKHLREVGIKPLADL-AVGYNLQDH---------TAPAVTFT 362
            ||||:|.||||:||||||||:|.|..|:::||..:..| .||.|||||         |.|....:
Human   290 KEVILSGGAINSPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQQACTRPITLHS 354

  Fly   363 TNATSLKFEDFSDPTLINRFNRMEGPYGSPGGCEAIAF-WDLDHERDEDGWPDIELFLVGGSMSS 426
            ......|.                        |..:.: |..   ..|.....:|   .||.:.|
Human   355 AQKPLRKV------------------------CIGLEWLWKF---TGEGATAHLE---TGGFIRS 389

  Fly   427 NPAISRAFGLKKSIYDTLFAEIEDKSLN---------AFMIFPMILRPKSRGRIMLKSSDPFKYP 482
            .|.:...        |..|..:..:.::         |:.:....:|..|.|.:.|:|::|..:|
Human   390 QPGVPHP--------DIQFHFLPSQVIDHGRVPTQQEAYQVHVGPMRGTSVGWLKLRSANPQDHP 446

  Fly   483 LIHANYFAHPYDVD---ISVRGLLKAISLMEQ----RGME-----KINARLWEKKIPTCKQHPYK 535
            :|..||.:...|::   :.|: |.:.|...|.    ||.|     .|.:   :|:|.
Human   447 VIQPNYLSTETDIEDFRLCVK-LTREIFAQEALAPFRGKELQPGSHIQS---DKEID-------- 499

  Fly   536 SWAYWACYVRHFTFTIYHYSGTAKMGPKSDRAAVVDHRLRVHGIKNLRVADASIMPEIMSGHPNG 600
                  .:||....:.||.|.|.|||..||..||||.:.||.|::||||.||||||.::||:.|.
Human   500 ------AFVRAKADSAYHPSCTCKMGQPSDPTAVVDPQTRVLGVENLRVVDASIMPSMVSGNLNA 558

  Fly   601 PVFMIAEKAADMIK 614
            |..||||||||:||
Human   559 PTIMIAEKAADIIK 572

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9521	NP_572977.1	BetA	57..617	CDD:441878	205/599 (34%)
CHDH	NP_060867.2	PRK02106	40..594	CDD:235000	205/599 (34%)