Protein Alignment CG9521 and Chdh

DIOPT Version :9

• Sequence 1: NP_572977.1
• Gene: CG9521 / 32414
• FlyBaseID: FBgn0030588
• Length: 621
• Species: Drosophila melanogaster
• Sequence 2: NP_942026.1
• Gene: Chdh / 290551
• RGDID: 735166
• Length: 599
• Species: Rattus norvegicus
• Alignment Length: 608
• Identity: 205/608 - (33%)
• Similarity: 286/608 - (47%)
• Gaps: 127/608 - (20%)

  Fly    59 EYDFIVVGAGTAGCALAARLSENPQWRVLLLEAG------GPERLV----MDVPIVAHFLQLGEM 113
            ||.|||||||:|||.||.||:|:|..||||||||      |.:||.    |...:||:... .:.
  Rat    45 EYTFIVVGAGSAGCVLANRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVANLCD-DKY 108

  Fly   114 NWKYRT--QPSDHACLAMNNNRCNWPRGKVMGGSSVLNYMMYTRGNRRDYDRWEALGNPGWSFKD 176
            ||.|.|  ||      .::.....||||:|.||||.||.|:|.||:..||:||...|..||.:..
  Rat   109 NWYYHTEAQP------GLDGRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHRQGAEGWDYAH 167

  Fly   177 VLPYFKKYE----GSSVPDAEEDYVGRNGPVKVSYVNWRSKIAEAFVDAAQQDGLKY-RDYNGRI 236
            .||||:|.:    |:::      |.|.:||:.||.......:.:||:.||:|.|..: .|.||..
  Rat   168 CLPYFRKAQKHELGANM------YRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQ 226

  Fly   237 QNGVAFLHTTTRNSTRWSSNRAYLYPLKGKRSNLHVRKNALVTKVLIDPQTKTAYGIMVQTEGRM 301
            |.|..::..|.....|||:..|||.|.. .|.||......||::||.  :...|.|:....:|:.
  Rat   227 QEGFGWMDMTIHQGKRWSTASAYLRPAL-SRPNLRAEVQTLVSRVLF--EGTRAVGVEYIKDGQS 288

  Fly   302 QKILARKEVIVSAGAINTPQLLMLSGVGPAKHLREVGIKPLADL-AVGYNLQDH---------TA 356
            .|....:|||:|.||||:||||||||||.|..|:::||..:..| .||.|||||         |.
  Rat   289 HKAYVSREVILSGGAINSPQLLMLSGVGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQHACTQ 353

  Fly   357 PAVTFTTNATSLKFEDFSDPTLINRFNRMEGPYGSPGGCEAIAF-WDLDHERDEDGWPDIELFLV 420
            |....:......|.                        |..:.: |..   ..:.....:|   .
  Rat   354 PITLHSAQKPLRKV------------------------CIGLEWLWRF---TGDGATAHLE---T 388

  Fly   421 GGSMSSNPAISRAFGLKKSIYDTLFAEIEDKSLN---------AFMIFPMILRPKSRGRIMLKSS 476
            ||.:.|.|.:...        |..|..:..:.::         |:.:....:|..|.|.:.|:|:
  Rat   389 GGFIRSRPGVPHP--------DIQFHFLPSQVIDHGRKPTQQEAYQVHVGTMRATSVGWLKLRST 445

  Fly   477 DPFKYPLIHANYFAHPYDVDISVRGLLKAISLMEQ----------RGME-----KINARLWEKKI 526
            :|..:|:|:.||.:...||:    ...:.:.|..:          ||.|     .:.:   :|:|
  Rat   446 NPQDHPMINPNYLSTETDVE----DFRQCVKLTREIFAQEAFAPFRGKELQPGSHVQS---DKEI 503

  Fly   527 PTCKQHPYKSWAYWACYVRHFTFTIYHYSGTAKMGPKSDRAAVVDHRLRVHGIKNLRVADASIMP 591
            .              .:||....:.||.|.|.|||..||..||||.:.||.|::||||.||||||
  Rat   504 D--------------AFVRAKADSAYHPSCTCKMGQPSDPTAVVDQQTRVIGVENLRVIDASIMP 554

  Fly   592 EIMSGHPNGPVFMIAEKAADMIK 614
            .::||:.|.|..||||||||:||
  Rat   555 SVVSGNLNAPTIMIAEKAADVIK 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9521	NP_572977.1	PRK02106	57..614	CDD:235000	203/606 (33%)
		NADB_Rossmann	61..>92	CDD:304358	22/30 (73%)
		NADB_Rossmann	125..356	CDD:304358	94/245 (38%)
		GMC_oxred_C	465..609	CDD:282984	53/158 (34%)
Chdh	NP_942026.1	PRK02106	45..591	CDD:235000	205/608 (34%)
		NADB_Rossmann	49..>151	CDD:304358	50/108 (46%)
		GMC_oxred_N	121..344	CDD:279121	94/231 (41%)
		GMC_oxred_C	435..572	CDD:282984	53/157 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	244	1.000	Domainoid score	I2129
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	342	1.000	Inparanoid score	I2269
OMA	1	1.010	-	-		QHG52181
OrthoDB	1	1.010	-	-		D173099at33208
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm44531
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.780