Protein Alignment CG9521 and Chdh

DIOPT Version :9

• Sequence 1: NP_572977.1
• Gene: CG9521 / 32414
• FlyBaseID: FBgn0030588
• Length: 621
• Species: Drosophila melanogaster
• Sequence 2: NP_001129712.1
• Gene: Chdh / 218865
• MGIID: 1860776
• Length: 596
• Species: Mus musculus
• Alignment Length: 603
• Identity: 205/603 - (33%)
• Similarity: 291/603 - (48%)
• Gaps: 117/603 - (19%)

  Fly    59 EYDFIVVGAGTAGCALAARLSENPQWRVLLLEAG------GPERLV----MDVPIVAHFLQLGEM 113
            ||.|:|||||:|||.||:||:|:|..||||||||      |.:||.    |...:|::... .:.
Mouse    42 EYTFVVVGAGSAGCVLASRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVSNLCD-DKY 105

  Fly   114 NWKYRTQPSDHACLAMNNNRCNWPRGKVMGGSSVLNYMMYTRGNRRDYDRWEALGNPGWSFKDVL 178
            ||.|.|:|..    .|::....||||:|.||||.||.|:|.||:..||:||...|..||.:...|
Mouse   106 NWYYHTEPQP----GMDSRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAEGWDYAHCL 166

  Fly   179 PYFKKYE----GSSVPDAEEDYVGRNGPVKVSYVNWRSKIAEAFVDAAQQDGLKY-RDYNGRIQN 238
            |||:|.:    |:::      |.|.:||:.||.......:.:||:.||:|.|..: .|.||..|.
Mouse   167 PYFRKAQRHELGANM------YRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQE 225

  Fly   239 GVAFLHTTTRNSTRWSSNRAYLYPLKGKRSNLHVRKNALVTKVLIDPQTKTAYGIMVQTEGRMQK 303
            |..::..|.....|||:..|||:|:. .|.||......||::||.  :...|.|:....:|:..|
Mouse   226 GFGWMDMTVHQGKRWSTACAYLHPVL-SRPNLRAEVQTLVSRVLF--EGTRAVGVEYIKDGQRHK 287

  Fly   304 ILARKEVIVSAGAINTPQLLMLSGVGPAKHLREVGIKPLADL-AVGYNLQDH---------TAPA 358
            ....:|||:|.||||:||||||||||.|..||::.|..:..| .||.|||||         |.|.
Mouse   288 AYVSREVILSGGAINSPQLLMLSGVGNADDLRKLDIPVVCHLPGVGQNLQDHLEVYVQQACTQPI 352

  Fly   359 VTFTTNATSLKFEDFSDPTLINRFNRMEGPYGSPGGCEAIAF-WDLDHERDEDGWPDIELFLVGG 422
            ...:......|.                        |..:.: |..   ..:.....:|   .||
Mouse   353 TLHSAQKPLRKV------------------------CIGLEWLWSY---TGDGATAHLE---TGG 387

  Fly   423 SMSSNPAISRAFGLKKSIYDTLFAEIEDKSLN---------AFMIFPMILRPKSRGRIMLKSSDP 478
            .:.|.|.:...        |..|..:..:.::         |:.:....:|..|.|.:.|:|::|
Mouse   388 FIRSRPGVPHP--------DIQFHFLPSQVIDHGRKPTQQEAYQVHVGTMRATSVGWLKLRSANP 444

  Fly   479 FKYPLIHANYFAHPYDVD-------ISVRGLLKAISLMEQRGME-----KINARLWEKKIPTCKQ 531
            ..:|:||.||.:...||:       :| |.:....:|...||.|     .:.:   :|:|.
Mouse   445 RDHPVIHPNYLSTETDVEDFRQCVRLS-REIFAQEALAPFRGKELQPGSHVQS---DKEID---- 501

  Fly   532 HPYKSWAYWACYVRHFTFTIYHYSGTAKMGPKSDRAAVVDHRLRVHGIKNLRVADASIMPEIMSG 596
                      .:||....:.||.|.|.|||..||..||||.:.:|.|::||||.||||||.::||
Mouse   502 ----------AFVRAKADSAYHPSCTCKMGRSSDPTAVVDAQTKVIGVENLRVVDASIMPSVVSG 556

  Fly   597 HPNGPVFMIAEKAADMIK 614
            :.|.|..||||||||:||
Mouse   557 NLNAPTVMIAEKAADIIK 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9521	NP_572977.1	PRK02106	57..614	CDD:235000	203/601 (34%)
		NADB_Rossmann	61..>92	CDD:304358	21/30 (70%)
		NADB_Rossmann	125..356	CDD:304358	95/245 (39%)
		GMC_oxred_C	465..609	CDD:282984	55/155 (35%)
Chdh	NP_001129712.1	PRK02106	42..588	CDD:235000	205/603 (34%)
		NAD_binding_8	47..>76	CDD:290186	21/28 (75%)
		GMC_oxred_N	118..341	CDD:279121	94/231 (41%)
		GMC_oxred_C	432..569	CDD:282984	55/154 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	241	1.000	Domainoid score	I2232
eggNOG	1	0.900	-	-		E1_COG2303
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	336	1.000	Inparanoid score	I2378
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52181
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000165
OrthoInspector	1	1.000	-	-		otm42468
orthoMCL	1	0.900	-	-		OOG6_100146
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X135
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.770